A kind of immune adjuvant of chicken infectious bursal disease live vaccine effervescent tablet

Abstract

The invention discloses an effervescent tablet immunologic adjuvant for a chicken infectious bursal disease live vaccine, which belongs to the technical field of veterinary biological products. The effervescent tablet immunologic adjuvant in each 1,000 ml of phosphate buffer comprises the following components: 30-80 g of traditional Chinese medicine polysaccharide, 20-50 g of traditional Chinese medicine flavonoid, 6-10 g of vitamins, 4-6 g of gelatin and 40-70 g of cane sugar. The effervescent tablet immunologic adjuvant disclosed by the invention has the advantages that the immunologic adjuvant has a heat resistant effect and is capable of improving the convenience for vaccine transportation, storage and the like; when a vaccine prepared from the immunologic adjuvant is adopted during inoculation, the stress reaction can be alleviated and the disease infection risk of chicken flocks is reduced; when the immunologic adjuvant is used for preparing the vaccine, the use effect of the live vaccine can be greatly improved and a neutralizing antibody is quickly produced.

Description

technical field [0001] The invention belongs to the technical field of veterinary biological products, and in particular relates to an immune adjuvant for chicken infectious bursal disease live vaccine effervescent tablet. Background technique [0002] With the rise of intensive poultry farming and the increase of international trade, poultry diseases are becoming more and more serious, resulting in high mortality of poultry, which seriously restricts the development of the poultry industry, causes serious losses to the world's poultry industry, and endangers economic development, food security and social stability. Chicken infectious bursal disease (Infection bursal disease, IBD) is a highly contagious disease of chickens and turkeys caused by infectious bursal virus (Infection bursal disease virus, IBDV). For young chickens at the age of one week, the virus mainly proliferates in the lymphocytes of the bursa of Fabricius, and causes varying degrees of damage to other immu...

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Problems solved by technology

Clinically, this disease can lead to symptoms such as weight loss, slow growth, and skeletal muscle hemorrhage. Under the condition of poor sanitation, it is often accompanied by other diseases, and the mortality rate is further increased. The chicks are small and have poor disease resistance. Once the epidemic occurs, Then the infection is fast, the mortality rate is high, the mortality rate reaches more than 80%, and the loss is even greater, which brings huge economic losses to the chicken industry.

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