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A method for extracting active ingredients from snow lotus

A technology of active ingredients and snow lotus, applied in the field of extracting active ingredients from snow lotus, can solve the problems of high production cost, low extraction efficiency, residual organic solvent harmful substances, etc., to reduce the investment and cost of production equipment, prolong the shelf life, and improve production. The effect of efficiency

Active Publication Date: 2018-03-02
BEIJING ALCHEMIST TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, the extracting method of active ingredients in Saussurea oleifera mainly adopts organic solvent extraction, such as the disclosed Saussurea chinensis extract of CN102240254A, methanol, ethanol, isopropanol, 1-butanol, ethylene glycol, 1,2-propanediol, 1 , 3-propanediol, 1,3-butanediol, acetone, ethyl acetate and various organic solvents to extract Saussurea sauraceae, the disadvantage of this method is that the organic solvent will remain as harmful substances, polluting the extract and the environment
CN101041653 discloses a method for extracting and enriching total flavonoids of Snow Lotus, which uses supercritical carbon dioxide extraction method to extract Saussurea Lotus, although this method alleviates the problem of harmful substances remaining caused by traditional organic solvents to a certain extent, but Due to the need to maintain the carbon dioxide in a critical state during the extraction process, the performance of the process equipment and the control precision of the production process are relatively high, and the pipeline layout of the relevant upstream and downstream equipment is intricate, and the production cost is high
[0009] More importantly, the traditional organic solvent extraction method usually can only extract one or several active ingredients in Saussurea chinensis, the extraction efficiency is low, and the efficacy of Saussurea sauraceae cannot be fully, effectively exerted and retained.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Take a completely dried snow lotus flower, first manually remove impurities, chop it into pieces with a length and width of about 2mm, and then add soft water equal to the weight of the snow lotus (that is, the quality of the snow lotus: the quality of soft water = 1:1), Crush in a blender until it becomes a paste to obtain a snow lotus paste. The snow lotus paste after the above pretreatment is heated up to 50-60°C and then kept warm, and then DSM's model is added Validase TRL (a mixture of cellulose and hemicellulase) and Rapidase TF (hemicellulose) under the condition of heat preservation. Sulfase and the mixture of pectinase) cellulase, the mass ratio of the two enzymes is 1:1, and the total usage is 0.05% of the mass of Snow Lotus. At the same time, adjust the pH value of the solution to 5.5. The heat preservation hydrolysis time is 2 hours. The temperature of the enzymatically hydrolyzed snow lotus solution is raised to 80-90° C. and kept for 5 minutes to inacti...

Embodiment 2

[0037] Take a completely dried snow lotus flower, remove impurities by hand, chop it into pieces with a length and width of about 2mm with a grinder, then add soft water, quality of snow lotus: quality of soft water = 1:1, crush it in a blender until it becomes a paste The snow lotus paste is obtained. The snow lotus paste after the above pretreatment is warmed up to 50-60°C and then kept warm, then DSM’s model is added ValidaseTRL (a mixture of cellulose and hemicellulase) and Rapidase TF (hemicellulose) under the condition of heat preservation. Enzyme and pectinase mixture) cellulase, the mass ratio of the two enzymes is 1:1, and the total usage is 0.05% of the mass of Snow Lotus. At the same time, adjust the pH value of the solution to 5.5. The heat preservation hydrolysis time is 2 hours. The temperature of the enzymatically hydrolyzed snow lotus solution is raised to 80-90° C. and kept for 5 minutes to inactivate the added cellulase. The solution after deactivating the...

Embodiment 3

[0040] Take a completely dried snow lotus flower, remove impurities by hand, chop it into pieces with a length and width of about 2mm with a grinder, then add soft water, quality of snow lotus: quality of soft water = 1:3, crush it in a blender until it becomes a paste The snow lotus paste is obtained. The snow lotus paste after the above pretreatment is warmed up to 50-60°C and then kept warm, then DSM’s model is added ValidaseTRL (a mixture of cellulose and hemicellulase) and Rapidase TF (hemicellulose) under the condition of heat preservation. Enzyme and pectinase mixture) cellulase, the mass ratio of the two enzymes is 1:1, and the total usage is 0.05% of the mass of Snow Lotus. At the same time, adjust the pH value of the solution to 5. The heat preservation hydrolysis time is 2 hours. The temperature of the enzymatically hydrolyzed snow lotus solution is raised to 80-90° C. and kept for 5 minutes to inactivate the added cellulase. The solution after deactivating the e...

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PUM

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Abstract

The invention discloses a method for extracting effective components from saussurea involucrate. The method is characterized by comprising the following steps: (1) removing impurities from totally dried saussurea involucrata by hands, cutting up into debris with around 2mm length and width, adding soft water, smashing into a paste in a stirrer to obtain a saussurea involucrata paste; (2) heating up the saussurea involucrata paste to 50-60DEG C, carrying out heat preservation for 1-3 hours and adding cellulase for hydrolyzing so as to obtain saussurea involucrata enzymatic hydrolysate, (3) heating up the saussurea involucrata enzymatic hydrolysate to 80-90DEG C, and carrying out heat preservation for 4-6 minutes to inactivate the added cellulase; (4) filtering the inactivated saussurea involucrata enzymatic hydrolysate by a 400-mesh sieve, and taking the filtrate to reserve for later use; (5) heating up the filtrate to more than 60DEG C, adding food grade maltodextrin and concentrated whey protein, stirring and dissolving, homogenizing to form a uniform and stable saussurea involucrata solution; and (6) carrying out spray drying on the uniform and stable saussurea involucrata solution, so as to form microcapsule saussurea involucrata powder.

Description

technical field [0001] The invention relates to the field of extracting active ingredients of plants, in particular to a method for extracting active ingredients from snow lotus. Background technique [0002] Snow lotus, called Chaguosuba in Tibetan, is called Kaleili by people in Xinjiang and Tibet. It is a perennial herb of Compositae. The species include: snow lotus with cotton head, snow lotus with big bud, snow lotus with jellyfish and other whole plants with flowers. [0003] Snow lotus is mainly distributed in the Tianshan Mountains in Xinjiang, Qamdo area of ​​Tibet and the high mountains with an altitude of 4500-4800 meters in the northwest of Sichuan. In Qinghai, Yunnan, Gansu and other provinces and autonomous regions, there are also other kinds of "sausaria" distributed, but the plants are slightly smaller. Snow lotus like leaves is very small, only a few centimeters high, and there are white or dark brown fluff on the inflorescence. Although there are many ki...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/285A61K9/50A61K47/42A61P29/00A61P19/02A61P11/14A61P1/00A61P13/12A61P15/08A61P15/10A61P15/00
Inventor 吕雷张冬柏
Owner BEIJING ALCHEMIST TECH
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