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Traditional Chinese medicine for treating yang-deficiency water-flooding type chronic cardiac insufficiency and preparation method thereof

A technology for cardiac insufficiency and yang deficiency and water flooding, applied in the field of pharmacy, can solve problems such as many adverse reactions, drug withdrawal reactions, and life-threatening, and achieve significant curative effect, improve respiratory function, and control blood pressure

Inactive Publication Date: 2014-11-19
朱靖
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] Western medicine treats chronic cardiac insufficiency, the course of treatment is longer, and there are many adverse reactions. Sudden withdrawal of the drug may cause withdrawal reactions, and severe cases may be life-threatening.
[0018] However, Chinese medicine has unique advantages and characteristics in the treatment of chronic cardiac insufficiency, which can make up for the shortcomings of Western medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0084] Wherein, when the dosage form of the Chinese medicine is a honey-refined pill, its preparation method comprises the following steps:

[0085] Step 1: first mix Poria cocos, coix seed, corn silk, Hovenia dulcis, tangerine peel and woody fragrance according to the stated ratio, and distill and crystallize to obtain powder;

[0086] Step 2: Take the remaining raw materials and mix them according to the ratio, add 2-6 times the amount of 83-94% ethanol to soak for 1-2 hours, heat and extract twice, each time for 1-1.5 hours, and combine the extracts , 124-150 mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 4400-98000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.04 at 87°C, which becomes component 1;

[0087] Step 3: Soak the dregs of the traditional Chinese medicine in step 2 with 4-6 times the amount of water for 1-2.5 hours, extract once, the extracti...

Embodiment 1

[0102] Embodiment 1 honey refining pill of the present invention

[0103] Take Poria cocos 30g, coix seed 27g, corn silk 34g, Hovenia dulcis 25g, tangerine peel 17g, woody 28g, agarwood 8g, bergamot 19g, citron 32g, scallion 22g, big belly skin 38g, sword bean 17g, radish seed 8g, Chicken Yateng 23g, White Mustard Seed 21g, Inulae 7g, Baiqian 24g, Campanulaceae 29g, Perilla Seed 16g, Manshanhong 7g, Huashan Ginseng 5g, Coltsfoot Flower 14g, Morus alba 21g, Codonopsis 26g, Chinese Yam 22g, Thorn Wujia 35g, Ziheche 9g, Cynomorium 14g, Polygonatum 21g, Field Curly 14g and Gorse 5g.

[0104] Its preparation method comprises the following steps:

[0105] Step 1: first mix Poria cocos, coix seed, corn silk, Hovenia dulcis, tangerine peel and woody fragrance according to the stated ratio, and distill and crystallize to obtain powder;

[0106] Step 2: Take the remaining raw materials and mix them according to the ratio, add 3 times the amount of 94% ethanol to the mixture, soak for ...

Embodiment 2

[0110] Embodiment 2 Tablet of the present invention

[0111] Take Poria cocos 21g, coix seed 20g, corn silk 26g, Hovenia dulcis 19g, tangerine peel 29g, woody fragrance 31g, agarwood 17g, bergamot 33g, citron 25g, scallion 25g, big belly skin 29g, sword bean 24g, radish seed 17g, Chicken Yateng 19g, White Mustard Seed 30g, Inulae 10g, Baiqian 33g, Campanulaceae 19g, Perilla Seed 15g, Manshanhong 13g, Huashan Ginseng 11g, Coltsfoot Flower 21g, Morus alba 13g, Codonopsis 14g, Yam 15g, Thorn Wujia 25g, Ziheche 11g, Cynomorium 7g, Polygonatum 26g, Field Curly 25g and Gorse 6g.

[0112] Its preparation method comprises the following steps:

[0113]The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 5 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating yang-deficiency water-flooding type chronic cardiac insufficiency and a preparation method thereof, wherein the traditional Chinese medicine comprises the following raw medicinal materials: poria cocos, coix seed, corn stigma, semen hoveniae, dried orange peel, radix aucklandiae, agilawood, fructus citrus sarcodactylis, fructus citri, allium macrostemon, betelnut peel, sword bean, semen raphani, paederia scandens, semen brassicae, inula flower, cynanchum glaucescens, platycodon root, fructus perillae, folium rhododendri daurici, radix physochlainae, flos farfarae, cortex mori, radix codonopsis, Chinese yam, radix acanthopanacis semticosi, human placenta, cynomorium songaricum, radix polygonati officinalis, cerastiumrvense L. and gorse. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicine has the efficacies of warming yang to promote diuresis, and mainly treats the yang-deficiency water-flooding type chronic cardiac insufficiency; with utilization of a traditional Chinese medicine theory and through adjustment of the whole blood circulation, the traditional Chinese medicine improves qi and blood of body circulation and pulmonary circulation, treats based on syndrome differentiation, is capable of adjusting arrhythmia, controlling blood pressure, improving body water and electrolyte disorder, enhancing a heart blood-pumping function, improving a respiratory function and the like, has multiple target spots, allows drug efficacy to directly reach nidi, is remarkable in curative effect, and is safe and effective.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating chronic heart insufficiency due to yang deficiency and water generalization and a preparation method thereof. [0002] Background technique [0003] Cardiac insufficiency, also known as "heart failure", is a syndrome of heart pumping insufficiency. It means that under the condition of proper venous return, the heart cannot expel enough blood to meet the needs of systemic tissue metabolism. The human body can mobilize compensatory mechanisms in the early stage to maintain the stability of the systemic circulation, such as myocardial hyperplasia, increasing preload, reflexively exciting sympathetic nerves, and even activating the renin-angiotensin-aldosterone system and arginine vasopressin system, At this time, the heart function is in the stage of complete compensation. However, with the development of the disease, the sympathetic n...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P9/04A61P9/00A61K35/50
Inventor 朱靖孔春妍刘芳王健
Owner 朱靖
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