Use of N-acetyl-5-methoxytryptamine or analogues thereof, for promoting the mechanism of implantation of the embryo and related compositions and culture media

A technology of methoxytryptamine and acetyl, applied in the field of N-acetyl-5-methoxytryptamine or its analogues for promoting the mechanism of embryo implantation, as well as related compositions and culture media, can solve the problem of High risk of endometrial cancer and other issues
CN104334167AInactive Publication Date: 2015-02-04ARES TRADING SA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ARES TRADING SA
Publication Date
2015-02-04
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention refers to the use of N-acetyl-5-methoxytryptamine (melatonin) and / or an analogue thereof, for use in the medical or veterinary field in the assisted reproduction for promoting the mechanism of implantation of the embryo, and in particular for the prevention of implantation failure into the uterus, by topical administration of an effective amount in a mammalian subject female in need of such treatment, and related compositions, culture media and medical devices.
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Description

technical field

[0001] The present invention relates to the application of N-acetyl-5-methoxytryptamine (melatonin) and / or its analogues, as well as related compositions, culture media and medical devices, said N-acetyl-5-methoxytryptamine Oxytryptamine (melatonin) and / or analogs thereof are useful for promoting the mechanism of embryo implantation in assisted reproduction in the medical or veterinary field by topical administration of an effective amount to a female mammalian subject in need of treatment, In particular, it is used to prevent failure of implantation in the uterus. Background technique

[0002] Human embryo implantation into the uterus is a complex mechanism involving both the embryo and the endometrial epithelium. The stages of apposition, adhesion, and invasion involve a variety of molecules that play unique roles in the process, and the molecular dialogue between pregnancy and the endometrium implies intercellular and cellular and biochemical factors int...

Claims

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