Three-dimensional cavitation quantitative imaging method for microsecond-distinguished cavitation time-space distribution

Abstract

The invention provides a three-dimensional cavitation quantitative imaging method for microsecond-distinguished cavitation time-space distribution. The three-dimensional cavitation quantitative imaging method comprises the following steps: after wide beams are used for detecting the cavitation, an array transducer is moved by one unit position; after the cavitation-nucleus distribution is restored, and under the excitation of same cavitation energy, the wide beams are reused for detecting the cavitation, space-series two-dimensional cavitation original radio-frequency data with different unit positions is obtained; time-sequence two-dimensional cavitation original radio-frequency data can be obtained by changing the energy acting time of a cavitation source, the time delay between the excitation of an energy source device and the wide beams transmitted by the array transducer and the time delay between a pulsating pump and excitation of the energy source device; then a microsecond-distinguished cavitation three-dimensional time-space distribution image and a quantitative image of cavitation microbubble density can be obtained by combining minimum-variance self-adaptive beam synthesis of the wide beams, Nakagami parameter imaging and a three-dimensional reconstruction algorithm, and the time resolution can reach microseconds. The method has the potential of being developed into a standard three-dimensional cavitation imaging method similar to soundfield measurement.

Description

technical field

[0001] The invention relates to the field of cavitation physics and application and ultrasonic imaging technology. The method combines array Plane-by-plane wide-beam cavitation detection, wide-beam minimum variance adaptive beam synthesis and Nakagami parameter imaging algorithm to realize steady-state free field and pulsation Microsecond resolution imaging of three-dimensional space-time distribution of cavitation and quantitative imaging of cavitation microbubble density under flow conditions. Background technique

[0002] Cavitation refers to the activation of cavitation nuclei in liquids under the action of external energy (heat / force), and a series of dynamic processes such as oscillation, growth, shrinkage and even collapse of micro-bubble nuclei occur. , gene transfection, in vitro lithotripsy, thrombolysis, hemostasis, hyperthermia, and tumor thermal ablation. The process of cavitation includes the following stages: cavitation nucleation, linear and ...

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