A kind of compound safflower sugar-free granule

A technology of compound safflower and granules, which is applied in the field of medicine, can solve the problems of granules that are easy to deliquescence, not suitable for long-term storage, softening and deterioration, etc., and achieve the effects of improving immunity, solving obesity, and enhancing resistance

Inactive Publication Date: 2018-02-02
SHAOXING UNIV YUANPEI COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the above-mentioned technical problems of the prior art, the object of the present invention is to provide a compound safflower sugar-free granule, which solves the problem of deliquescence, softening and deterioration, and unfavorable long-term use of the granule due to the high sugar content of the granule for a long time. Insufficient existing, thus improving the drug stability, ensuring the clinical efficacy of the drug, and expanding the scope of application, so that many elderly and sugar-free patients, especially diabetic patients, can lift the drug restrictions

Method used

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  • A kind of compound safflower sugar-free granule
  • A kind of compound safflower sugar-free granule
  • A kind of compound safflower sugar-free granule

Examples

Experimental program
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Effect test

preparation example Construction

[0066] (4) Preparation of wet granules: Extrude the prepared soft material through a 12-mesh sieve to obtain compound safflower sugar-free wet granules;

[0067] (5) Drying: Put the compound safflower sugar-free wet granules in an oven at a temperature of 50-60°C to dry;

[0068] (6) Grain sizing: take the above dry granules and pass through 10-mesh and 30-mesh sieves for sizing.

Embodiment 1

[0070] Prescription composition: safflower extract 50g, ginkgo leaf extract 25g, seabuckthorn flavonoids 5g, scallion 5g, donkey-hide gelatin 2.5g, seaweed polysaccharide sulfate 2.5g, dextrin 162g and aspartame 0.75g.

[0071] Preparation method: take the above-mentioned amount of safflower extract, ginkgo leaf extract, seabuckthorn flavonoids, scallions, donkey-hide gelatin, seaweed polysaccharide sulfate, dextrin and aspartame, grind them separately, pass through a 100-mesh sieve for later use; extract safflower Ginkgo biloba extract, seabuckthorn flavonoids, scallions, donkey-hide gelatin, seaweed polysaccharide sulfate and dextrin are added and mixed evenly, and then aspartame is added and mixed evenly to obtain a mixed medicinal powder; an appropriate amount of 85% Mix ethanol to make the soft material, so that the soft material meets the requirement of "forming into a ball when grasped, and then disperses when pressed lightly"; the prepared soft material is squeezed thro...

Embodiment 2

[0073] Prescription composition: safflower extract 50g, ginkgo leaf extract 25g, seabuckthorn flavonoids 5g, scallion 5g, donkey-hide gelatin 2.5g, seaweed polysaccharide sulfate 2.5g, dextrin 135g and aspartame 0.68g.

[0074] The preparation method of this Example 2 is the same as that of Example 1, and will not be repeated here.

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Abstract

The invention relates to a compound safflower sugar-free granule preparation, which comprises main ingredients and auxiliary ingredients. The main ingredients are safflower extract, ginkgo leaf extract, seabuckthorn flavonoids, scallions, donkey-hide gelatin and seaweed polysaccharide sulfate. The auxiliary material components are wetting agent, diluent and sugar-free flavoring agent. The invention solves the long-standing problems of deliquescence, softening and deterioration, and unsuitable long-term storage of the granules caused by the high sugar content of the granules, thereby improving the stability of the medicine, ensuring the clinical curative effect of the medicine, and expanding the application range, so that many elderly and sugar-free patients, especially diabetic patients, can lift the drug restrictions.

Description

technical field [0001] The invention belongs to the technical field of medicine, relates to a pharmaceutical composition comprising safflower, in particular to a compound safflower sugar-free granule preparation for treating cardiovascular and cerebrovascular diseases. Background technique [0002] Safflower is the dried tubular flower of safflower (Carthamus tinctorius L.), a plant of Compositae. It is a traditional medicinal plant in my country. The main components of safflower are dihydroflavonoids: safflower glycosides, safflower pigments, safflower pigments A, B, C, etc., lignans, and volatile oils. The water-soluble safflower yellow pigment is considered to be the main effect substance of safflower. Safflower yellow has curative effect on coronary heart disease, vascular embolism disease, hypertension, diabetes complications, and has analgesic effect and anti-inflammatory effect, the curative effect is very significant. At present, there are more than 200 chemical co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8962A61K9/16A61P9/00A61K35/36
Inventor 张娜
Owner SHAOXING UNIV YUANPEI COLLEGE
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