A flexible hydrosol adjuvant for ophthalmology

Abstract

The invention relates to medical preparations, in particular to a flexible hydrosol auxiliary agent for ophthalmology, which consists of: 0.2% to 0.5% of disodium hydrogen citrate, 1% to 1.5% of monosodium hydrogen citrate, and hydroxypropyl methylcellulose 5%~8%, sodium chondroitin sulfate 0.5%~1%, potassium chloride 0.5%~2%, magnesium chloride 0.3%~0.8%, sodium acetate 0.3%~1.5%, sodium chloride 1.3%~2.5%, no Bacteria double distilled water 85 ~ 90%. There can also be sodium hyaluronate 1% to 3%. The present invention is under the premise of ensuring the performance of the product, reducing the risk of nucleation and deposition, and slowing down the turbidity of the lens. Significantly reduced the consumption of disodium hydrogen citrate and magnesium chloride. It reduces the irritation to the patient's eyes, and avoids complications such as itching, tearing, redness and swelling in the patient's eyes. At the same time, the bionic level of the preparation is improved. The stability of the preparation is significantly improved, and it is suitable for long-term use, and has good effects as eye care, anti-dryness and anti-fatigue.

Description

technical field [0001] The invention relates to medical preparations, in particular to a flexible hydrosol adjuvant used in ophthalmic surgery and treatment. Background technique [0002] Cataract is a common eye disease that can cause clouding of the lens in mild cases and lead to blindness in severe cases. According to the 2010 annual report of the World Health Organization, about 48% of the 18,000,000 blind patients in the world are caused by cataracts caused by aging. At present, China has the largest blind population in the world, about 6,600,000 people, and about 50% of them are caused by cataracts. As my country's population ages, this number will increase significantly. [0003] The mode of treating cataract in the prior art is surgical implantation of intraocular lens. The selection and use of flexible hydrosol adjuvants in surgery is very important, because in the process of injecting the intraocular lens into the anterior chamber of the eyeball through the Scle...

AI Technical Summary

Problems solved by technology

[0005] However, these flexible hydrosol adjuvants for intraocular lens implantation generally have the following deficiencies: 1) Due to the large number of polar functional groups contained in them, the surface electron density is increased and the interface energy between the complex and the body fluid is reduced at the same time

2) The presence of a large number of phosphate radicals will induce the supersaturated deposition of calcium phosphate, which will directly lead to a decrease in product stability and eventually lead to lens turbidity

[0007] However, when this technology is used in clinical observation, whether it is used in intraocular lens implantation surgery or as ordinary eye drops, some users report itchy eyes, excessive tears, and even some redness and swelling and other similar allergies. The problem

Images