Unlock instant, AI-driven research and patent intelligence for your innovation.

System and method for controlling bioactivator separation and purification process

A bioactive substance and process control system technology, applied in the direction of medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, pharmaceutical formulations, etc., can solve the problem of long cycle time, non-continuous operation, and degree of automation low level problem

Active Publication Date: 2015-09-16
HARBIN INST OF TECH
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problems of inability to operate continuously in the separation and purification of biological active substances, resulting in low yield, low efficiency, high cost, long cycle time, serious pollution, poor product quality stability, and low degree of automation, the invention provides a biological Active substance separation and purification process control system and method

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • System and method for controlling bioactivator separation and purification process
  • System and method for controlling bioactivator separation and purification process
  • System and method for controlling bioactivator separation and purification process

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0086] Specific implementation mode one: as Figure 1-7As shown, the biologically active substance separation and purification process control system described in this embodiment includes an extraction kettle 1, a heater 2, a heater hot water storage tank 2-1, a buffer tank 3, a solvent recovery tank 4, a concentrator 5, a concentrator Solvent recovery tank 5-1, concentrated storage tank 6, chromatography column 7, high-purification horizontal tank 8, condensation system 9, pure water tank 10, analysis tank 11, acid tank 12, alkali tank 13, deployment tank 14, Solvent storage tank 15, low purification horizontal tank 16, infusion pump, control valve, sewage treatment tank 17. Each device is connected by pipelines and control valves according to the process control. The specific connection relationship is as follows:

[0087] A stirring pump P9 and an ultrasonic generator are installed on the extraction kettle 1. The feed port of the extraction kettle 1 is connected to the tap...

specific Embodiment approach 2

[0145] Specific implementation mode 2: In this implementation mode, a specific implementation case is given, and the extraction solvent and elution solvent used are ethanol solutions.

[0146] The extraction raw material of this embodiment is pulverized plant powder.

[0147] The separation medium used in this embodiment is a macroporous resin.

[0148] The acid solution used in this embodiment is hydrochloric acid.

[0149] The alkali used in this embodiment is sodium hydroxide.

[0150] This embodiment includes the entire series of processes for the separation and purification of biologically active substances.

[0151] This embodiment includes the following seven control processes:

[0152] 1. Extraction process:

[0153] Step 1: Start the two-way solenoid valve D18 (0, 2), the infusion pump P8, the two-way solenoid valve D24 (0, 1) and the one-way solenoid valve S1, and close the two-way solenoid valve D18 ( 0, 2), infusion pump P8, two-way solenoid valve D24 (0, 1) a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a system and method for controlling the bioactivator separation and purification process. The system comprises an extraction kettle, a heater, a heater hot water storage tank, a buffer tank, a solvent recovery tank, a concentrator, a concentrator solvent recovery tank, a concentration storage tank, a chromatographic column, a horizontal high-purification tank, a pure water tank, an analysis tank, an acid tank, an alkali tank, a preparation tank, a solvent storage tank, a horizontal low-purification tank and a sewage treatment tank. The system and method for controlling the bioactivator separation and purification process have the advantages that the whole separation and purification process is conducted at normal temperature, and the processing stability of products is guaranteed; continuous operation of large-scale production is achieved; the separation and purification cycle is shortened, and operation difficulty is lowered; product processing cost is reduced; product quality is improved; sewage treatment is achieved.

Description

technical field [0001] The invention belongs to the field of automatic control, and relates to a system and a method for controlling the separation and purification process of biologically active substances. Background technique [0002] In modern society, bioactive substances have a wide range of application values ​​due to their biological activities such as anti-oxidation, whitening, anti-tumor, immune regulation, anti-inflammation, lowering blood fat, lowering blood pressure, anti-cardiovascular disease and anti-neurodegenerative diseases, and are often used in Food, medicine, health care products and cosmetics make important contributions to human health. Bioactive substances are mainly derived from natural plant and microbial resources, and high-value products need to be separated and purified. However, the separation of bioactive substances in the industrial field is still mainly intensive manual operation, and the production equipment is outdated. , the technical co...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/00A61K35/66
Inventor 王振宇李辉伊娟娟
Owner HARBIN INST OF TECH