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Medicine for preventing or treating type A influenza and hand, foot, and mouth disease

A technology for hand, foot and mouth disease and drugs, applied in antiviral agents, pharmaceutical formulas, plant raw materials, etc., can solve the problems of poor oral bioavailability, ineffective effect, strong therapeutic effect, etc., to prevent influenza A and hand, foot and mouth disease , no toxic side effects, easy to use

Active Publication Date: 2015-11-11
贵州中医药大学第二附属医院 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, oseltamivir has a lot of side effects, especially for children, and its side effects are stronger than the therapeutic effect
Although zanamivir has significant curative effect and few side effects, its oral bioavailability is poor, and other administration methods such as intranasal administration, intradermal or intravenous injection are cumbersome to administer and poor in safety
It can be seen that antiviral drugs are not only ineffective in treating children with influenza A and hand, foot and mouth disease, but also have large side effects and poor safety

Method used

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  • Medicine for preventing or treating type A influenza and hand, foot, and mouth disease
  • Medicine for preventing or treating type A influenza and hand, foot, and mouth disease
  • Medicine for preventing or treating type A influenza and hand, foot, and mouth disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Prescription: Clove 10g, Huoxiang 10g, Angelica dahurica 10g, Perilla leaf 10g, Atractylodes 10g, Magnolia 10g, Baikouren 10g, Cinnamon 5g, Artemisia argyi 15g, Nepeta 10g.

[0064] Process: Take the above-mentioned medicines, and under the condition of 10-15°C, grind them into fine powders of 60-70 mesh respectively at low temperature, mix them evenly, put them into cloth bags, 6g in each bag, and obtain the sachet.

[0065] Usage and dosage: wear the sachet on the chest or in the coat pocket every day, put it next to the pillow or in the handbag, or hang the sachet indoors, and replace it every 10-15 days.

Embodiment 2

[0067]Prescription: 20g of cloves, 20g of Huoxiang, 20g of Angelica dahurica, 20g of perilla leaves, 20g of herb, 20g of magnolia, 20g of white kohlrabi, 15g of cinnamon, 30g of mugwort leaves, and 20g of nepeta. Process: Take the above drug, extract it with steam distillation for 1 hour, collect the condensate, let it stand for stratification, separate the volatile oil, and set aside; add 10 times the amount of water to the drug dregs after extracting the volatile oil, decoct 3 times, the first time 2 hours , 1 hour for the second time, 1 hour for the third time, filter, combine the filtrates, concentrate to an extract with a relative density of 1.15 to 1.25 at 60 ° C, mix with the above-mentioned volatile oil to obtain a decoction.

[0068] Usage and dosage: take orally, 10-15g each time, 3 times a day.

Embodiment 3

[0070] Prescription: Clove 1kg, Huoxiang 1kg, Angelica dahurica 1kg, Perilla leaf 1kg, Atractylodes 1kg, Magnolia 1kg, Baikouren 1kg, Cinnamon 1kg, Artemisia argyi 5kg, Nepeta 1kg.

[0071] Process: Take the above drug, add 8 times the amount of 70% ethanol to reflux and extract twice, the first time is 2 hours, the second time is 1 hour, filter, combine the filtrate, and the relative density of the filtrate is 1.15 when the ethanol is recovered and concentrated to 60°C ~1.25 extract, dry at 60°C, 0.07Mpa~0.08Mpa, pass through 80 mesh sieve, add 25% mixed auxiliary materials to mix evenly, the mixed auxiliary materials are composed of microcrystalline cellulose and corn starch at a ratio of 1:1 90% ethanol is used as a wetting agent to make granules, dried at 60°C after granulation, passed through a 12-mesh sieve once, and sieved into a fine powder with a 60-mesh sieve, filled into capsules, each 0.3 g, to obtain capsules.

[0072] Usage and dosage: take orally, 3-5 capsules ...

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Abstract

The invention discloses a medicine for preventing or treating type A influenza and hand, foot, and mouth disease. The medicine is prepared mainly by using clove, Agastache rugosus, dahurian angelica root, perilla leaf, atractylodes rhizome, biond magnolia flower-bud, cardamon fruit, cassia bark, argy wormwood leaf, fineleaf schizonepeta herb spike and minor ingredients. The medicine can effectively prevent or treat type A influenza and hand, foot, and mouth disease. A perfume satchel can prevent can prevent children from catching type A influenza and hand, foot, and mouth disease, is convenient to use and does not do harm to body health of children.

Description

Field of invention: [0001] The invention relates to a medicine for preventing or treating influenza A and hand-foot-mouth disease, belonging to the technical field of traditional Chinese medicine. technical background: [0002] Both influenza A and HFMD are diseases that seriously endanger human health. Influenza A, also known as influenza A H1N1, is an acute respiratory infectious disease caused by influenza A H1N1 virus. This virus strain contains three influenza virus gene segments: swine flu, bird flu and human influenza. Symptoms are similar to those of the common cold, including fever, cough, sore throat, body aches, headache, chills, and fatigue. Some may also experience diarrhea or vomiting, muscle pain or tiredness, and red eyes. The condition of some patients can develop rapidly, with fierce onset, sudden high fever, body temperature over 38°C, and even secondary severe pneumonia, acute respiratory distress syndrome, pulmonary hemorrhage, pleural effusion, systemi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P31/14A61P31/16
Inventor 彭玉
Owner 贵州中医药大学第二附属医院
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