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CO2 supercritical extraction traditional Chinese medicine parotid gland treatment capsules and preparation method thereof

A traditional Chinese medicine treatment and supercritical technology, which is applied in capsule delivery, medical formula, drug combination, etc., can solve the problems of incomplete extraction of active ingredients of traditional Chinese medicine, loss of active ingredients, large drinking volume, etc., to eliminate odor and adverse stimulation, step by step Simple, cost-saving effect

Inactive Publication Date: 2016-03-02
刘海燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, when taking traditional Chinese medicine, it is necessary to add decoction and decoct to extract the medicinal ingredients. Not only the amount of drinking is large, but also very cumbersome, which causes a lot of inconvenience to patients; and the traditional method of extraction can not completely extract the active ingredients of Chinese medicine, making Chinese medicine loss of active ingredients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] (1) Raw material components 16 grams of Scutellaria baicalensis, 16 grams of Coptis chinensis, 45 grams of Radix Scrophulariae, 7 grams of Burdock, 7 grams of Cimicifuga, 7 grams of Puffball, 7 grams of Mint, 45 grams of Bupleurum, 7 grams of dried stems, 45 grams of Radix Radix gram, 7 grams of silkworm, 45 grams of forsythia, 7 grams of orange, 7 grams of licorice.

[0016] (2) The process preparation steps are as follows:

[0017] ?Material preparation: remove impurities from the raw material components, crush them, pass through a 60-mesh sieve, and take the sieved material to obtain a mixed powder;

[0018] ?Extraction: Using supercritical extraction equipment, put the mixed powder into supercritical CO 2 In the extraction kettle of the extraction equipment, add ethanol with an entrainer content of 60% to immerse the mixed powder, and use supercritical CO 2 It is the extraction solvent, the extraction temperature is 40°C, the extraction pressure is 20Mpa, the extr...

Embodiment 2

[0022] (1) Raw material components: 17 grams of Scutellaria baicalensis, 17 grams of Coptis chinensis, 46 grams of Scrophulariaceae, 8 grams of Burdock, 8 grams of Cimicifuga, 8 grams of puffball, 8 grams of mint, 46 grams of Bupleurum, and 8 grams of dried stems 46 grams of isatidis, 8 grams of silkworm, 46 grams of forsythia, 8 grams of orange, 8 grams of licorice.

[0023] (2) The process preparation steps are as follows:

[0024] ?Material preparation: remove impurities from the raw material components, crush them, pass through a 60-mesh sieve, and take the sieved material to obtain a mixed powder;

[0025] ?Extraction: Using supercritical extraction equipment, put the mixed powder into supercritical CO 2 In the extraction kettle of the extraction equipment, add ethanol with an entrainer content of 60% to immerse the mixed powder, and use supercritical CO 2 It is the extraction solvent, the extraction temperature is 50°C, the extraction pressure is 15Mpa, the extraction ...

Embodiment 3

[0029] (1) Raw material components: 19 grams of Scutellaria baicalensis, 19 grams of Coptis chinensis, 47 grams of Scrophulariaceae, 9 grams of Burdock, 9 grams of Cimicifuga, 9 grams of puffball, 9 grams of mint, 47 grams of Bupleurum, and 9 grams of dried stems. grams, 47 grams of isatidis, 9 grams of silkworm, 47 grams of forsythia, 9 grams of orange, 9 grams of licorice.

[0030] (2) The process preparation steps are as follows:

[0031] ?Material preparation: remove impurities from the raw material components, crush them, pass through a 60-mesh sieve, and take the sieved material to obtain a mixed powder;

[0032] ?Extraction adopts supercritical extraction equipment, put the mixed powder into supercritical CO 2 In the extraction kettle of the extraction equipment, add ethanol with an entrainer content of 60% to immerse the mixed powder, and use supercritical CO 2 It is the extraction solvent, the extraction temperature is 30°C, the extraction pressure is 30Mpa, the ext...

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Abstract

The invention discloses CO2 supercritical extraction traditional Chinese medicine parotid gland treatment capsules and a preparation method thereof. The CO2 supercritical extraction traditional Chinese medicine parotid gland treatment capsules are prepared from scutellaria baicalensis, coptis chinensis, radix scrophulariae, burdock, rattletop, puffball, mint, radix bupleuri, dried stalk, isatis roots, stiff silkworm, fructus forsythia, chrysoidine and liquorice; material preparation, extraction, granulation, sterilization and packaging are adopted for preparing the parotid gland treatment capsules. Effective components of the raw materials are extracted through supercritical CO2, and the capsules have the advantages of being high in extraction rate and low in operation temperature, not damaging traditional Chinese medicine effective components, and being free of organic solvent residues and simple in technology, and the obtained capsules can be taken instantly, are convenient to store and can be carried with a person, the apozem decoction process is omitted, and specific odor and poor stimulation during traditional Chinese medicine apozem taking are eliminated; the finished capsules have the effects of warming spleen and stomach for dispelling cold, replenishing qi to invigorate the spleen and regulating qi to alleviate pain, have the effects of isolating and protecting gastric mucosa and reinforcing repairing of the gastric mucosa, and meanwhile have the effects of clearing away heat and toxic materials and resolving hard lumps.

Description

technical field [0001] The present invention relates to the technical field of traditional Chinese medicine ointment, especially a kind of CO 2 Supercritical extraction of traditional Chinese medicine to treat parotid gland capsules and its preparation method. Background technique [0002] Mumps is also called mumps, subotitis, commonly known as "pig scalp" and "mump", which refers to the inflammation of one or two parotid glands (the main salivary glands on both sides of the human cheek); the parotid gland is the most salivary gland A frequently inflamed site; the most common cause of parotitis is infection with the mumps virus; obstruction of the main parotid gland or its branches is usually the main cause of acute parotitis, and further infection may even lead to bacterial superinfection . It is an acute respiratory infectious disease caused by mumps virus invading the parotid gland. It is a common respiratory infectious disease in children and adolescents, and it also ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61K9/48A61P31/14A61P1/00A61K35/64
Inventor 刘海燕
Owner 刘海燕
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