Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Toothpaste containing oral cavity probiotics

A technology of probiotics and probiotic freeze-dried powder, which is applied in the field of toothpaste containing oral probiotics, can solve the problems that probiotics cannot be stored at room temperature and bacteria are inactivated, and achieve the goal of eliminating oral odor, nourishing gums, and ensuring oral health Effect

Active Publication Date: 2016-03-30
南昌理工学院
View PDF7 Cites 16 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of the defect that probiotics cannot be stored at room temperature, the present invention uses the freeze-dried powder of oral probiotics to replace live bacteria, but the change in the permeability of the bacterial cell membrane during the freeze-drying process will usually cause the bacteria to be inactivated. The inventors It was found that adding a certain amount of fructooligosaccharides, microcrystalline cellulose and vitamin D during the freeze-drying process can effectively protect the bacteria from the freeze-drying process.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Toothpaste containing oral cavity probiotics
  • Toothpaste containing oral cavity probiotics
  • Toothpaste containing oral cavity probiotics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] A toothpaste containing oral probiotics, in parts by weight, consists of the following components:

[0015] 1 part of probiotic freeze-dried powder, 0.01 part of sodium glutamate, 0.1 part of calcium chloride, 0.5 part of carboxymethyl cellulose, 8 parts of sorbitol, 8 parts of glycerin, 0.4 part of sodium benzoate, 0.3 part of titanium dioxide, silicon dioxide 30 parts, 0.8 parts of sodium monofluorophosphate, 1 part of peppermint oil, 20 parts of distilled water, 2 parts of sodium lauroyl sarcosinate.

[0016] Among the above components, the freeze-drying process of the probiotic freeze-dried powder is as follows: 1. The probiotic culture solution is centrifuged at a speed of 7000r / min for 15 minutes to obtain the probiotic slime; 2. Add oligomeric bacteria to the probiotic slime. Fructose, microcrystalline cellulose and vitamin D, the weight ratio of probiotic bacteria slime, fructooligosaccharide, microcrystalline cellulose and vitamin D are: 80 parts of probiotic b...

Embodiment 2

[0021] A toothpaste containing oral probiotics, in parts by weight, consists of the following components:

[0022] 3 parts of probiotic freeze-dried powder, 0.03 part of sodium glutamate, 0.2 part of calcium chloride, 1.0 part of carboxymethyl cellulose, 10 parts of sorbitol, 9 parts of glycerin, 0.6 part of sodium benzoate, 0.4 part of titanium dioxide, silicon dioxide 40 parts, 1.0 parts of sodium monofluorophosphate, 1.5 parts of peppermint oil, 25 parts of distilled water, 3 parts of sodium lauroyl sarcosinate.

[0023] Among the above components, the freeze-drying process of the probiotic freeze-dried powder is as follows: 1. The probiotic culture solution is centrifuged at a speed of 7500r / min for 18 minutes to obtain the probiotic slime; 2. Add oligomeric bacteria to the probiotic slime Fructose, microcrystalline cellulose and vitamin D, the weight proportion of probiotic bacteria slime, fructo-oligosaccharide, microcrystalline cellulose, vitamin D is: 90 parts of probi...

Embodiment 3

[0026] A toothpaste containing oral probiotics, in parts by weight, consists of the following components:

[0027] 5 parts of probiotic freeze-dried powder, 0.05 parts of sodium glutamate, 0.3 parts of calcium chloride, 2 parts of carboxymethyl cellulose, 12 parts of sorbitol, 10 parts of glycerin, 0.8 parts of sodium benzoate, 0.5 parts of titanium dioxide, silicon dioxide 45 parts, 1.2 parts of sodium monofluorophosphate, 2 parts of peppermint oil, 30 parts of distilled water, 4 parts of sodium lauroyl sarcosinate.

[0028] Among the above components, the freeze-drying process of the probiotic lyophilized powder is as follows: 1. The probiotic culture solution is centrifuged at a speed of 8000r / min for 20 minutes to obtain the probiotic slime; 2. Add oligomeric bacteria to the probiotic slime. Fructose, microcrystalline cellulose and vitamin D, the weight ratio of probiotic bacteria slime, fructo-oligosaccharide, microcrystalline cellulose, vitamin D is: 100 parts of probiot...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a toothpaste containing oral cavity probiotics. The added probiotics are added in the form of probiotic freeze-dried powder, and fructooligosaccharide and microcrystalline cellulose are added in freeze drying process, so that damage on the probiotics in freeze drying is avoided; sodium glutamate and calcium chloride are also added into the toothpaste, so that a problem that yellowing of probiotic toothpast is easily caused is solved. It is confirmed by clinical experiments that the toothpaste containing oral cavity probiotics possesses excellent curative effect on gingivitis, periodontitis, and ozostomia.

Description

technical field [0001] The invention relates to the technical field of oral health care, in particular to a toothpaste containing oral probiotics. Background technique [0002] The oral cavity is the first gateway to human health, and the human oral cavity environment is a complex ecosystem containing a variety of microorganisms. The excessive growth and reproduction of certain microorganisms which are harmful to oral health can lead to the occurrence of dental caries, periodontitis and bad breath. The treatment by taking antibiotics will destroy the balance of the oral ecosystem, and the treatment effect is often unsatisfactory. Therefore, maintaining the balance of oral flora is the key to creating a healthy oral environment. Although our daily actions such as brushing teeth and gargling can interfere with the reproduction of oral bacteria, they cannot fundamentally improve the oral environment. [0003] We know that the key to maintaining the balance of intestinal flor...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K8/99A61K8/73A61K8/67A61K8/60A61K8/44A61K8/20A61Q11/00
CPCA61K8/20A61K8/44A61K8/60A61K8/67A61K8/731A61K8/99A61K2800/84A61Q11/00
Inventor 杨秀英邱敏蓉
Owner 南昌理工学院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com