Clean production process for converting camphor ammonium sulfonate into camphorsulfonic acid

Abstract

The invention discloses a clean production process for converting camphor ammonium sulfonate into camphorsulfonic acid. The clean production process comprises the following steps of step 1, filtering a feed solution by a ceramic membrane to obtain a ceramic membrane dialysate; step 2, enabling the ceramic membrane dialysate to enter into a continuous ion exchange system for performing continuous ion exchange to obtain a camphorsulfonic acid solution, and filling a separation unit of the continuous ion exchange system with strong acid cation exchange resin; step 3, performing reverse osmosis concentration on the camphorsulfonic acid solution to obtain a camphorsulfonic acid concentrated solution; step 4, performing mechanical steaming and compressive concentration on the camphorsulfonic acid concentrated solution, and then performing crystallization, centrifugal separation and crystal drying to obtain a camphorsulfonic acid crystal. The camphorsulfonic acid crystal produced by the clean production process for converting the camphor ammonium sulfonate into the camphorsulfonic acid, disclosed by the invention, can reach 99.5 percent or over 99.5 percent in purity, reaches the pharmaceutical grade level of the camphorsulfonic acid, and has the advantages of high yield, simple working procedure, good conversion effect, high purity of product, compact equipment, small occupied area and the like.

Description

technical field [0001] The invention relates to the field of camphorsulfonic acid production, in particular to a clean production process for converting ammonium camphorsulfonate into camphorsulfonic acid. Background technique [0002] Camphor mainly exists in camphor plant camphor wood, zingiberaceae and alpiniae seeds, and is an indispensable raw material for medicine, daily use and national defense industry. According to its source, camphor is mainly divided into two categories: natural and synthetic. Natural camphor is mainly extracted from the essential oils of Lauraceae plants, and generally has dextrorotatory optical activity; synthetic camphor is made from turpentine through major chemical reactions such as isomerization, acetic acid addition esterification, hydrolysis and dehydrogenation, and is racemized. body. [0003] Camphorsulfonic acid is a derivative of camphor and has a chiral counterpart structure. According to its optical properties, it can be divided in...

AI Technical Summary

Problems solved by technology

At present, the chemical industry synthesizes camphorsulfonic acid mainly by first synthesizing sodium camphorsulfonate or ammonium camphorsulfonate solution, and then making camphorsulfonic acid solution through continuous ion exchange in a fixed bed; Low, poor product purity needs further separation and purification, etc.

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