Method for extracting sulphuretin and butein with tyrosinase inhibitory activity from wood powder of lacquer tree

A technology of purpurin and thioflavin, applied in the directions of organic chemistry, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as weak utilization of lacquer seeds, and achieve the effects of high activity, simple process operation and easy implementation.
CN105837540AActive Publication Date: 2016-08-10INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY
Publication Date
2016-08-10

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Abstract

The invention relates to a method for extracting sulphuretin and butein with inhibitory activity from wood powder of a lacquer tree, belonging to the field of development and application of natural pharmaceutical chemistry and cosmetics. High-content sulphuretin and butein compounds can be rapidly and effectively prepared from the wood powder of the lacquer tree through abstraction, extraction, silica gel column chromatography and low-and-medium pressure chromatography. Sulphuretin and butein monomers prepared in the invention have low-concentration tyrosinase inhibitory activity and pose no toxic and harmful effect to human beings; the tyrosinase inhibition rates of the monomers are greater than 95% when the concentrations of the monomers are 50 [mu]g / mL; preparation process is simple and fast; the monomers are good sources for development of potential natural tyrosinase inhibitors, can be applied to preparation of whitening cosmetics and for prevention and treatment of hyperpigmentation diseases caused by excess melanin in the human body, and have good commercial prospects.
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Description

technical field

[0001] The invention relates to a method for extracting thiosulfanthin and butacein which have the activity of inhibiting tyrosinase from sumac powder, and belongs to the technical fields of natural medicine and cosmetics. Background technique

[0002] Sumac (Rhus verniciflua stokes) is a deciduous tree of the Anacardiaceae genus Toxicodendron. Sumac is an important special-purpose economic forest in my country. Raw lacquer is a natural resin coating and is known as the "king of coatings". It is also an excellent medicinal wood. The leaves, flowers, roots, bark, fruits, dried lacquer and wood core of sumac tree can be used as medicine, which has the effects of relieving cough, eliminating addiction, stimulating menstrual flow, killing insects, and reducing swelling. The polyphenolic compound in the part is the main active substance after urushiol and urushiol, and a large number of studies have shown that it has excellent antioxidant, antitumor, antibacterial a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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