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Traditional Chinese and western medicine compound eye drops for treating bacterial coronitis and preparation method thereof

A technology for keratitis and compound eyes, which is applied in the field of medicine, can solve the problems of slow effect and achieve short treatment course, low cost and strong pertinence

Inactive Publication Date: 2016-11-23
周艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the medicines for treating bacterial keratitis are mainly western medicines. For example, frequent eye drops with high concentration of antibiotic eye drops in the acute stage can relieve the disease. However, traditional Chinese medicine actually has a better treatment for this disease, but the effect is slightly slower than western medicine. Therefore, it is very valuable to develop a kind of eye drops for bacterial keratitis with definite and fast curative effect by combining western medicine and traditional Chinese medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The raw material composition and weight of the eye drops composition of the present invention are: 84 parts of dog seedlings, 81 parts of spit iron, 79 parts of joint grass, 77 parts of betel leaves, 74 parts of angelica, 69 parts of syringa, 66 parts of scorpion seeds, 64 parts of mosaic leaves, 62 parts of cypress leaves, 59 parts of amaranth fruit, 57 parts of banyan gum juice, 55 parts of bamboo leaf plantain, 54 parts of vetch, 1.4 parts of olopatadine, 1.3 parts of carbacholine, norflu Shaxing 1.1 parts.

[0041] The processing step of eye drops preparation method of the present invention is:

[0042] (1) Put dog seedlings, spit iron, scorpion seeds and amaranth into a container, add 6 to 8 times the amount of distilled water relative to the mass of the mixture and soak for 2 to 3 days, then add 3 to 4 times the mass concentration of 45 % to 55% ethanol, heated and refluxed for 4 hours, filtered to obtain the extract; add distilled water of 4 to 6 times the quali...

Embodiment 2

[0050] The raw material composition and weight of the eye drops composition of the present invention are: 78 parts of dog seedlings, 75 parts of spit iron, 73 parts of joint grass, 71 parts of betel leaves, 68 parts of angelica, 63 parts of syringa, 61 parts of scorpion, 59 parts of mosaic leaves, 57 parts of cypress leaves, 53 parts of amaranth fruit, 51 parts of banyan gum juice, 49 parts of bamboo leaf plantain, 48 parts of vetch, 1.2 parts of olopatadine, 1.0 parts of carbacholine, norflu Shaxing 0.8 part.

[0051] The process steps, usage and dosage of the eye drops preparation method of this embodiment are the same as those of Embodiment 1.

Embodiment 3

[0053] The raw material composition and weight of the eye drops composition of the present invention are: 71 parts of dog seedlings, 68 parts of spit iron, 66 parts of joint grass, 64 parts of betel leaves, 61 parts of angelica, 56 parts of syringa, 54 parts of scorpion, 51 parts of mosaic leaves, 50 parts of cypress leaves, 46 parts of amaranth fruit, 44 parts of banyan gum juice, 42 parts of bamboo leaf plantain, 41 parts of vetch, 0.9 parts of olopatadine, 0.8 parts of carbacholine, norflu Shaxing 0.5 part.

[0054] The process steps, usage and dosage of the eye drops preparation method of this embodiment are the same as those of Embodiment 1.

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Abstract

The invention discloses traditional Chinese and western medicine compound eye drops for treating bacterial coronitis and a preparation method thereof, belonging to the technical field of medicines. The eye drops comprise the following raw materials: japanese calystegia, mud snail, marsh horsetail herb, betel leaf, angelica sinensis, zornia gibbosa, semen thlaspi, leaf of Chinese loropetalum, incised spleenwort, three-coloured amaranth seed, smallfruit fig resin, cannalike dona rhizome, common vetch, olopatadine hydrochloride, carbachol and norfloxacin. The eye drops disclosed by the invention adopt a therapeutic method of combining traditional Chinese medicine and western medicine, have excellent treatment effects compared with those of generally pure traditional Chinese and western medicine, take the effects of clearing away heat and toxic materials, diminishing inflammation and sterilizing, improving eyesight and relieving opacity, relieving swelling and pain and tonifying liver and nourishing kidney as treatment principles, can improve the effects of the traditional Chinese medicinal components and western medicine at the highest efficiency and improve medicinal effects, are externally and directly dripped into eyes so as to kill bacteria and realize high antibacterial property, can directly reach lesions, are convenient to use and good in absorption effect, do not have any bad and toxic or side effect, and have good effects of treating decreased eyesight, chemosis and the like caused by bacterial coronitis.

Description

Technical field [0001] The invention relates to the technical field of medicine, in particular to a Chinese and western compound eye drops for treating bacterial keratitis and a preparation method thereof. Background technique [0002] Bacterial keratitis is purulent keratitis caused by bacterial infection, also known as bacterial corneal ulcer. Bacterial keratitis is mostly caused by infection after trauma or removal of corneal foreign bodies, such as Staphylococcus, Bacteria, Streptococcus, Pseudomonas, etc., excessive use of antibiotics and glucocorticoids, dry eye, chronic dacryocystitis , diabetes, etc. can also cause the cornea to increase susceptibility to bacteria. [0003] Clinical manifestations of bacterial keratitis: [0004] 1. The onset is acute, usually 24 to 48 hours after corneal trauma. [0005] 2. Eye redness, pain, photophobia, tearing, decreased vision, blepharospasm and increased secretions. [0006] 3. Eyelid swelling, conjunctival edema, ciliary c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/08A61P27/02A61P31/04A61K35/618A61K31/496A61K31/335A61K31/27
CPCA61K9/0048A61K9/08A61K31/27A61K31/335A61K31/496A61K35/618A61K36/11A61K36/185A61K36/21A61K36/232A61K36/31A61K36/39A61K36/48A61K36/60A61K36/67A61K36/88A61K2236/31A61K2236/331A61K2236/333A61K2300/00
Inventor 周艳王东宝李若龙
Owner 周艳
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