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Medical hydrogel foam dressing and preparation method thereof

A hydrogel and foam technology, used in medical science, bandages, etc., can solve the problems of loss of bioactive substances, slow wound healing, and unfavorable epithelial cell crawling, so as to avoid secondary trauma, promote wound healing, and wound healing. good effect

Inactive Publication Date: 2017-05-31
SUZHOU AIBOMAIER NEW MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The traditional dry healing theory believes that wound healing requires a dry environment and the action of oxygen. However, in a dry environment, not only is it easy to dehydrate the wound and scab, it is not conducive to the crawling of epithelial cells, but it is also easy to lose biologically active substances. , resulting in slow wound healing, so it is necessary to provide a moist environment for the wound to promote rapid wound healing
[0003] Due to its gel state, medical hydrogel dressings can provide moisture to the wound, avoid dryness of the wound, and have a good moisturizing effect. It can not only effectively promote wound healing, but also play a role in preventing adhesion and avoiding secondary trauma. , however, hydrogel dressings cannot be applied to wounds with a lot of exudate, which limits its application to a certain extent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A medical hydrogel foam dressing, comprising the following components in parts by weight: 30 parts of polyurethane foam, 10 parts of pullulan, 5 parts of gelatin, 7 parts of konjac gum, 3 parts of keratin fiber, β- 2 parts of carotene, 4 parts of sodium D-glucuronate, 1 part of magnesium chloride, 0.5 parts of earthworm dry powder, 1.4 parts of ginkgo flavonoids, 2.2 parts of deer melon polypeptide, 2.1 parts of panaxtriol saponin, 6 parts of starch acrylic acid graft copolymer , 4 parts of trimethylolpropane glycidyl ether, 15 parts of glycerin, 20 parts of distilled water.

[0022] The keratin fiber is prepared from any one of human hair, cow hair, wool, pig hair and rabbit hair. The specific preparation steps are: placing the hair material in thioglycolic acid, It is obtained by immersing in an aqueous solution of thiourea and sodium lauryl sulfate at a temperature of 55°C for 24 hours, and then separated by dialysis and filtration, wherein the mass concentration of ...

Embodiment 2

[0030] A medical hydrogel foam dressing, comprising the following components in parts by weight: 46 parts of polyurethane foam, 16 parts of pullulan, 12 parts of gelatin, 11 parts of konjac gum, 10 parts of keratin fiber, β- 6 parts of carotene, 7 parts of sodium D-glucuronate, 3 parts of magnesium chloride, 2 parts of dry earthworm powder, 3 parts of ginkgo flavonoids, 4 parts of deer melon polypeptide, 4.3 parts of panaxtriol saponin, 14 parts of starch acrylic acid graft copolymer , 11 parts of trimethylolpropane glycidyl ether, 24 parts of glycerol, and 35 parts of distilled water.

[0031] The keratin fiber is prepared from any one of human hair, cow hair, wool, pig hair and rabbit hair. The specific preparation steps are: placing the hair material in thioglycolic acid, It is obtained by soaking in an aqueous solution of thiourea and sodium lauryl sulfate at a temperature of 55°C for 24 hours, and then separated by dialysis and filtration, wherein the mass concentration o...

Embodiment 3

[0039] A medical hydrogel foam dressing, comprising the following components in parts by weight: 33 parts of polyurethane foam, 11 parts of pullulan, 6.4 parts of gelatin, 7.5 parts of konjac gum, 3.2 parts of keratin fiber, β- 2.3 parts of carotene, 4.5 parts of sodium D-glucuronate, 1.4 parts of magnesium chloride, 0.8 parts of earthworm dry powder, 1.7 parts of ginkgo flavonoids, 2.4 parts of deer melon polypeptide, 2.7 parts of panaxtriol saponin, 7.2 parts of starch acrylic acid graft copolymer , 4.5 parts of trimethylolpropane glycidyl ether, 17 parts of glycerol, and 24 parts of distilled water.

[0040]The keratin fiber is prepared from any one of human hair, cow hair, wool, pig hair and rabbit hair. The specific preparation steps are: placing the hair material in thioglycolic acid, It is obtained by immersing in an aqueous solution of thiourea and sodium lauryl sulfate at a temperature of 55°C for 24 hours, and then separated by dialysis and filtration, wherein the ma...

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PUM

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Abstract

The invention discloses a medical hydrogel foam dressing. The medical hydrogel foam dressing is prepared from the following components: polyurethane foam, pullulan, gelatin, konjac glucomannan, keratin fiber, beta-carotene, sodium D-glucuronate, magnesium chloride, earthworm dry powder, ginkgo flavone, cervus and cucumis polypeptide, panaxtrial saponins, a starch acrylic acid graft copolymer, trimethylolpropane glycidyl ether, glycerin and distilled water. The invention also discloses a preparation method of the medical hydrogel foam dressing. After a medical hydrogel foam dressing product prepared by the embodiment of the invention is used for 3 days, the wound healing rate is greater than 65 percent, the wound healing time is short, the wound healing effect is good, no scars are generated after healing, no adhesion exists between a wound and the medical hydrogel foam dressing, so that secondary injury caused by dressing replacement is avoided, and the market prospect is wide.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a medical hydrogel foam dressing and a preparation method thereof. Background technique [0002] The traditional dry healing theory believes that wound healing requires a dry environment and the action of oxygen. However, in a dry environment, not only is it easy to dehydrate the wound and scab, it is not conducive to the crawling of epithelial cells, but it is also easy to lose biologically active substances. , resulting in slow wound healing, so it is necessary to provide a moist environment for the wound to promote rapid wound healing. [0003] Due to its gel state, medical hydrogel dressings can provide moisture to the wound, avoid dryness of the wound, and have a good moisturizing effect. It can not only effectively promote wound healing, but also play a role in preventing adhesion and avoiding secondary trauma. However, hydrogel dressings cannot be ap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0057A61L26/0004A61L26/0014A61L26/0019A61L26/0023A61L26/0028A61L26/0038A61L26/0042A61L26/0061A61L26/0066A61L26/008A61L26/0085A61L2300/216A61L2300/30C08L3/12C08L5/00C08L75/04C08L51/02
Inventor 李子寅花顺达
Owner SUZHOU AIBOMAIER NEW MATERIAL CO LTD
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