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Implantable neural electrode based on carbon nanotube line

A carbon nanotube, implantable technology, applied in the field of medical devices, can solve the problems of low mechanical damage, high signal-to-noise ratio, difficult biocompatibility of nerve electrodes, etc., achieve high charge injection capability, and improve signal-to-noise ratio. , the effect of superior tensile strength

Inactive Publication Date: 2017-07-21
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In view of the above-mentioned defects of the prior art, the technical problem to be solved by the present invention is that it is difficult for the existing nerve electrodes to have high biocompatibility, low mechanical damage, high signal-to-noise ratio and high charge injection ability at the same time, and cannot achieve long-term effective The problem of collecting and outputting bioelectrical signals

Method used

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  • Implantable neural electrode based on carbon nanotube line
  • Implantable neural electrode based on carbon nanotube line

Examples

Experimental program
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Effect test

Embodiment 1

[0030] Such as figure 1 As shown, two implantable nerve electrodes based on carbon nanotube wires are implanted into the same peripheral nerve bundle 4 of the peripheral nerve trunk 3, and are used to record the electrical signals of the peripheral nerve fibers in the state of motion and to monitor the peripheral nerve bundle 4. Local electrical stimulation. Among them, the implantable nerve electrode based on carbon nanotube wires includes an exposed part 1 and an insulating part 2, the exposed part 1 and the insulating part 2 are derived from the same carbon nanotube wire electrode, the carbon nanotube wire electrode of the exposed part 1 is directly exposed, and the insulating part The carbon nanotube wire electrode of 2 is wrapped by an insulating layer; the exposed part 1 is used for recording electrical signals or stimulating nerves.

[0031] The implantable nerve electrode material is a carbon nanotube wire, and the diameter of the carbon nanotube wire is 10 μm. The c...

Embodiment 2

[0036] Such as figure 2 As shown, two adjacent carbon nanotube wire electrodes are respectively implanted into the cerebral cortex to perform differential recording of electrical signals or local electrical nerve stimulation on the nerves of the brain; it is used to record the neural electrical activity of the motor cortex, or realize the Somatosensory cortex and visual cortex are electrically stimulated to realize somatosensory or visual feedback. Among them, the implantable nerve electrode based on carbon nanotube wires includes an exposed part 1 and an insulating part 2, the exposed part 1 and the insulating part 2 are derived from the same carbon nanotube wire electrode, the carbon nanotube wire electrode of the exposed part 1 is directly exposed, and the insulating part The carbon nanotube wire electrode 2 is wrapped by an insulating layer; the exposed part 1 is used for recording nerve electrical signals or performing electrical stimulation on nerves.

[0037]The mater...

Embodiment 3

[0042] Such as figure 2 As shown, two adjacent carbon nanotube wire electrodes are respectively implanted into the deep layer of the brain for deep brain neural electrical signal recording or electrical stimulation neural regulation. Among them, the implantable nerve electrode based on carbon nanotube wires includes an exposed part 1 and an insulating part 2, the exposed part 1 and the insulating part 2 are derived from the same carbon nanotube wire electrode, the carbon nanotube wire electrode of the exposed part 1 is directly exposed, and the insulating part The carbon nanotube wire electrode 2 is wrapped by an insulating layer; the exposed part 1 is used for recording nerve electrical signals or performing electrical stimulation on nerves.

[0043] The material of the implanted nerve electrode is a carbon nanotube wire, and the diameter of the carbon nanotube wire is 10 μm. The carbon nanotube wire is drawn from a plurality of single carbon nanotubes with a diameter of 5n...

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Abstract

The invention discloses an implantable neural electrode based on a carbon nanotube line, and relates to the field of medical equipment. The implantable neural electrode comprises an exposed part and an insulation part, wherein the exposed part and the insulation part are from the same carbon nanotube line electrode, the carbon nanotube line electrode of the exposed part is directly exposed, and the carbon nanotube line electrode of the insulation part is wrapped by an insulation layer; the exposed part is used for recording electroneurographic signals or conducting electrostimulation on nervous tissue. The disclosed neural electrode is small in size, has a flexible structure and makes close contact with neurons, which can reduce mechanical damages to the nervous tissue and contribute to achieving long-term and stable implantation in vivo. The carbon nanotube material used by the neural electrode has the advantage of being high in charge injection capacity. Not only can the neural electrode using the carbon nanotube line of small size record the electroneurographic signals with a high signal-to-noise ratio, but it can conduct partial neural electrostimulation, improving spatial selectivity of the neural electrode electrostimulation.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an implanted nerve electrode based on carbon nanotube wires. Background technique [0002] As a physical channel between the biological nervous system and artificial electronic devices, the performance of implantable nerve electrodes directly determines the long-term reliability of the acquisition of biological nerve electrical signals and nerve electrical stimulation. The design considerations of neural electrodes mainly include the biocompatibility and biosafety of materials, the mechanical and electrochemical stability of electrodes, and the repeatability of manufacturing processes. [0003] Traditional implantable nerve electrodes for peripheral and central nervous tissue mostly use polymers, platinum, iridium or silicon materials. Although the functions of electrodes can already be realized, it is difficult to achieve high biocompatibility, flexibility (that is, low mechanical...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/04A61N1/05A61L31/02
CPCA61B5/6877A61B2562/0209A61L31/024A61L31/14A61L2400/12A61N1/0526A61N1/0529A61N1/0531A61N1/0548A61N1/0551A61B5/24
Inventor 隋晓红朱丰源王逸林朱璟然
Owner SHANGHAI JIAO TONG UNIV
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