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Gynecologic vagina gel and preparing method thereof

A vaginal gel, women's technology, applied in the direction of antifungal agent, pharmaceutical formulation, aerosol delivery, etc., can solve the problems of repeated vaginitis, low vaginal immunity, dysbacteriosis in the vagina, etc., to prevent gynecology Vaginal inflammation, reduced recurrence rate, good stability

Inactive Publication Date: 2017-08-11
NANOLATTIX BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0022] In order to solve the problem that the traditional gynecological lotion kills pathogenic bacteria and many probiotics at the same time, leading to vaginal bacterial flora imbalance and low vaginal immunity, thus causing repeated episodes of vaginitis, the present invention provides a women's vaginal Gel and its preparation method

Method used

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  • Gynecologic vagina gel and preparing method thereof
  • Gynecologic vagina gel and preparing method thereof
  • Gynecologic vagina gel and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Example 1: A vaginal gel for women, prepared from the following parts by weight of raw materials: 150 parts of nanobubble hydrogen-rich water with a pH of 4.0-7.5, and artificial ionized acidic oxidizing water with a pH of 2.0-4.0 3000 parts, 30 parts of an aqueous gel matrix; the aqueous gel matrix is ​​a pharmaceutically acceptable gel matrix, such as water, glycerin, propylene glycol, triethanolamine, cellulose derivatives, carbomer, poloxamer, Carrageenan, chitosan and alginate, tragacanth, pectin, gelatin, xanthan gum, agar, non-cellulosic polysaccharide, ethylene polymer, acrylic resin, polyvinyl alcohol, carbopol, oily gel One or a mixture of several in any ratio; the aqueous gel matrix is ​​not limited to the above-mentioned gel matrixes, all pharmaceutically acceptable gel matrixes can be used; the prepared vaginal gel for women The pH of the agent is 3.8-6.0.

[0045] The preparation method is as follows: dissolve the aqueous gel matrix in artificial ionized aci...

Embodiment 2

[0047] Example 2: A vaginal gel for women, prepared from the following parts by weight of raw materials: 200 parts of nanobubble hydrogen-rich water with a pH of 4.0-7.5, and artificial ionized acidic oxidizing water with a pH of 2.0-4.0 2000 parts, water-based gel matrix, the water-based gel matrix is: 15-50 parts of carbomer, 2-4 parts of propylene glycol, 1-2 parts of triethanolamine, 25-300 parts of glycerin; prepared vaginal gel for women The pH of the agent is 3.8-5.5. The preparation method is the same as that described in Example 1. The nanobubbles hydrogen-rich water and artificial ionized acidic oxidation potential water can also be purchased from the market.

Embodiment 3

[0048] Example 3: A vaginal gel for women, prepared from the following parts by weight of raw materials: 300 parts of nanobubble hydrogen-rich water with a pH of 4.0-7.5, and artificial ionized acidic oxidizing water with a pH of 2.0-4.0 400 parts, an aqueous gel matrix, the aqueous gel matrix is: 5-30 parts of poloxamer, 80-200 parts of 1% propylene glycol, 1 part of triethanolamine, 2-10 parts of glycerin, prepared vaginal gel for women The pH of the glue is 3.8-5.5. The preparation method is the same as that described in Example 1.

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Abstract

The invention belongs to the technical field of gynecologic medicines and provides gynecologic vagina gel and a preparing method thereof to solve the problem that a traditional gynecologic cleaning solution kills many probiotics while killing pathogenic bacteria to cause dysbacteriosis in the vagina and vagina hypoimmunity, and colpitis recurrently attacks. Nano bubble hydrogen-enriched water, man-made ionized acidic electrolyzed oxidizing water and a hydrophilic gel matrix are mixed according to a certain ratio to prepare the gel with the pH value of 3.8-6.0. The gynecologic vagina gel maintains microecological balance of the vagina, improves the cleanliness degree of the vagina, improves the immunity of vagina mucosa and achieves the purposes of preventing gynecologic vagina inflammation and reducing the recurrence rate of gynecologic colpitis and is safer and more effective. The gynecologic vagina gel has the advantages of being high in transdermal absorption ratio, high in stability, convenient to deliver, good in vagina anelasticity, long in drug action time, not prone to deformation and easy to store, can fully release drugs, causes no foreign body sensation in the vagina, does not hurt the vagina and does not pollute clothes after being used.

Description

Technical field [0001] The invention belongs to the technical field of gynecological medication, and specifically relates to a vaginal gel for women and a preparation method thereof. Background technique [0002] The female vagina is an open cavity and is an important micro-ecological area in the human body. Normally, it is a micro-ecological system mainly composed of dominant bacteria. The imbalance of female vagina microecological is the main cause of recurrent inflammation of the gynecological vulva and vagina. Among the factors that maintain the vaginal microecological balance, estrogen, lactobacillus and vaginal pH (pH) play a vital role. Under normal physiological conditions, estrogen thickens the vaginal epithelium and is rich in glycogen, increasing the resistance to pathogens; glycogen is decomposed into lactic acid under the action of vaginal lactobacillus to maintain the normal acidic environment of the vagina (pH value 3.8~4.5), inhibit the growth of other parasitic...

Claims

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Application Information

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IPC IPC(8): A61K33/00A61K9/06A61K47/38A61K47/10A61K47/32A61K47/36A61K47/42A61P15/02A61P31/10A61P31/04A61P33/02A61P15/00
CPCA61K9/0036A61K9/06A61K33/00A61K47/10A61K47/32A61K47/36A61K47/38A61K47/42
Inventor 渠志灿李少平
Owner NANOLATTIX BIOTECH CO LTD
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