Traditional Chinese medicine composition for preventing and treating rheumatoid arthritis and preparation method thereof
A composition and arthritis technology, which is applied in the field of traditional Chinese medicine composition for preventing and treating rheumatoid arthritis and its preparation, can solve the problems of slow effect and long treatment time, and achieve slow and irregular absorption, less harsh process conditions, Good biocompatibility effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0051] Weigh 6 grams of Eucommia ulmoides, 6 grams of Sangjisheng, 7 grams of Clematis, 6 grams of Salvia miltiorrhiza, 5 grams of Dilong, 8 grams of Shengdi, 6 grams of papaya, 6 grams of black snake, 5 grams of Panax notoginseng, 5 grams of Duhuo, 5 grams of safflower, 6 grams of white peony, 6 grams of Caulis Spatholobus, 7 grams of angelica, and 3 grams of centipede.
[0052] Step 2, preparation of alcohol extract
[0053]Add the weighed Radix Paeoniae Alba, Eucommia, Clematis, Sangjisheng, Salvia, Panax notoginseng, Duhuo, and safflower to 75% ethanol and soak them, then reflux and extract at 90°C for 3 times to obtain the alcohol extract, and reflux 75% ethanol three times The addition amounts are as follows: the first time is 8 times the sum of the weighed Radix Paeoniae Alba, Eucommia, Clematis, Sangjisheng, Salvia, Panax notoginseng, Duhuo, and safflower, and the second time is 8 times the sum of the above masses , the third time is 6 times of the above mass sum.
...
Embodiment 2
[0061] 1. Investigation of the therapeutic activity of the traditional Chinese medicine composition of the present invention.
[0062] 1) Animal grouping and establishment of adjuvant arthritis rat model.
[0063] After adaptive feeding of SD rats for 2 weeks, 10 SD rats were randomly selected as the normal control group, and the remaining rats were used for modeling. After fasting for 12 hours, except for the normal control group, the rest of the rats were placed in cold water at 4°C-8°C with a water surface height of 2 cm. After 30 minutes, the rats were taken out, and the rats were dried with an electric fan. Intradermal injection of Freund's complete adjuvant 0.1 ml / rat, normal group of rats injected with an equal volume of normal saline, continuous 2 days. Nine days after the inflammation, the left hind feet of the rats successively appeared secondary arthritis symptoms (non-inflammation and joint redness and swelling of both forelimbs), listlessness, and loose hair, ind...
Embodiment 3
[0081] Comparison of the therapeutic effects of different dosage forms on cotton ball granuloma in rats with adjuvant arthritis.
[0082] The inventor conducted a comparative study on the therapeutic effect of the traditional Chinese medicine composition gel and ointment of the present invention on cotton ball granuloma in rats with adjuvant arthritis.
[0083] The components in Example 1 were pulverized, sieved through a 120-mesh sieve, mixed with the fine powder, added to rice wine, and stirred into a paste to obtain a pasty mixture, wherein every 100 g of the pasty mixture contained 30 g of the traditional Chinese medicine composition. Apply the obtained mixture evenly on the plaster to obtain the plaster of the present invention.
[0084] 40 rats were randomly divided into normal control group, model control group, traditional Chinese medicine gel group and traditional plaster group. Adjuvant arthritis rat model construction method and administration method are the same a...
PUM

Abstract
Description
Claims
Application Information

- Generate Ideas
- Intellectual Property
- Life Sciences
- Materials
- Tech Scout
- Unparalleled Data Quality
- Higher Quality Content
- 60% Fewer Hallucinations
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com