Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Laminin wound protective film

A technology of laminin and protective film, which is applied in the field of biomedicine, can solve the problems of nervous system damage, allergic reaction, reduction, etc., and achieve the effect of maintaining biological activity, enhancing repair, and reducing healing scars

Pending Publication Date: 2017-10-27
王丛飞
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, antibiotics can cause allergic reactions; drug resistance; reduction in white blood cells, red blood cells, and platelets; damage to the nervous system; Take advantage of the opportunity to reproduce in large numbers, causing bacterial flora imbalance and causing disease. Therefore, the indications of antibiotics should be strictly controlled to avoid unreasonable abuse of antibiotics

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 Gel

[0029] 1. The concentration of the capsule material of the animal plasma laminin microcapsule is 8%, and the ratio of the core material to the capsule material is 1:6; the specific preparation method comprises the following steps:

[0030] (1) Use absolute ethanol as a solvent to prepare a carboxymethyl cellulose capsule material solution with a concentration of 8%;

[0031] (2) Add laminin and capsule material into the capsule material solution at a ratio of 1:6, and homogenize twice at normal temperature and pressure of 40 MPa to obtain a uniform suspension;

[0032](3) The above-prepared suspension was first frozen in a -20°C refrigerator for 12 hours, and then transferred to a vacuum freeze dryer for drying for 16 hours. The obtained dry powder was laminin microcapsules.

[0033] 2. Take 30 parts of animal plasma laminin microcapsules prepared in the above step 1, 0.3 parts of carbomer, 15 parts of sodium alginate, 5 parts of medical glycerin, and m...

Embodiment 2

[0035] Embodiment 2: water agent

[0036] 1. The concentration of the capsule material of the animal plasma laminin microcapsule is 3%, and the ratio of the core material to the capsule material is 1:2; the specific preparation method comprises the following steps:

[0037] (1) Use absolute ethanol as a solvent to prepare a glyceride capsule material solution with a concentration of 3%;

[0038] (2) adding laminin and capsule material into the capsule material solution at a ratio of 1:2, and homogenizing twice at normal temperature and pressure of 40 MPa to obtain a uniform suspension;

[0039] (3) The above-prepared suspension was first frozen in a -20°C refrigerator for 10 hours, and then transferred to a vacuum freeze dryer for drying for 12 hours. The obtained dry powder was laminin microcapsules.

[0040] 2. Take 3 parts of animal plasma laminin microcapsules prepared in the above step 1, 2 parts of polyvinyl alcohol, 1 part of sodium alginate and 3 parts of medical glyc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a laminin wound protective film which takes animal plasma laminin as a main component and consists of a stroke-physiological saline solution and a pharmaceutical adjuvant. The laminin wound protective film comprises the following specific components in parts by weight: 1-30 parts of an animal plasma laminin micro-capsule, 0.1-30 parts of a film-forming substrate, 1-10 parts of a moisturizing agent and the rest part of stroke-physiological saline solution. The animal plasma laminin micro-capsule takes a laminin solution dissolved into water as a capsule core material and is coated with a capsule material; the film-forming substrate is one or more of polyvinyl alcohol, carbomer, sodium alginate and calcium alginate. The laminin wound protective film provided by the invention has the advantage that the laminin is made into the micro-capsule, so that while the biological activity of the micro-capsule is maintained, the shelf life is prolonged. The laminin wound protective film provided by the invention can be made into a water agent form or a gel form and is simple in preparation process and suitable for large-scale production. The laminin wound protective film provided by the invention can be directly sprayed and coated onto wounds of patients with burn, trauma, diabetic foot rot, ulcers, other chronic skin ulcers and the like and is convenient to use and good in treatment effect.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a laminin wound protective film. Background technique [0002] As we all know, once the human body is traumatized, if the wound is not well cared for, it will cause wound infection. In severe cases, it may suppurate and persist for a long time, and even cause systemic infection, gas gangrene, and tetanus, which are life-threatening. Wound infection is a pathological reaction in which pathogenic microorganisms invade the body through the wound, grow and multiply in the body, damage the normal function, metabolism, and tissue structure of the body, and cause tissue damage. The most commonly used anti-infective drugs are antibiotics. However, antibiotics can cause allergic reactions; drug resistance; reduction in white blood cells, red blood cells, and platelets; damage to the nervous system; Taking the opportunity to reproduce in large numbers, it will cause bacterial flora imbalance a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K38/39A61K9/70A61K47/32A61K47/36A61K47/10A61K47/44A61K9/50A61P17/02
CPCA61K38/39A61K47/10A61K47/32A61K47/36A61K47/44A61K9/5015A61K9/5031A61K9/5036A61K9/5047A61K9/7007
Inventor 王丛飞
Owner 王丛飞
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com