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Preparation and application of an antibacterial lubricant for tampon outer tube

A technology for tampons and lubricants, applied in pharmaceutical formulations, pharmaceutical sciences, microcapsules, etc., can solve the problems of easy discoloration, adverse effects on the environment and human health, skin irritation and allergy, etc. Scope, effect of strong antibacterial function

Active Publication Date: 2020-12-29
苏州宝丽洁医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The above-mentioned lubricants all use organic antibacterial and anti-corrosion materials, which have poor heat resistance and certain toxicity, which can easily cause irritation and allergies to the skin, and cause bacteria to develop drug resistance and mutate into super bacteria, which is even more harmful to the human body.
Although silver-based antibacterial agents have excellent antibacterial properties, the use of nano-silver also has disadvantages. The most prominent performances are that it is expensive, easy to change color, and the precipitation of silver ions causes pigmentation. In addition, silver ions are easy to cause adverse effects on the environment and human health.

Method used

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  • Preparation and application of an antibacterial lubricant for tampon outer tube
  • Preparation and application of an antibacterial lubricant for tampon outer tube
  • Preparation and application of an antibacterial lubricant for tampon outer tube

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Preparation and application of an antibacterial lubricant for the outer tube of a tampon. Nano-zinc oxide, nano-titanium oxide, cerium nitrate, and polyvinylpyrrolidone are dispersed in water at a molar ratio of 1:0.5:0.01:2.5 to prepare a 0.01M water dispersion Solution A; gradually add 20ml of aqueous solution A to 100ml of glycerin B dropwise under stirring to obtain a homogeneous system of water-in-oil; react in a hydrothermal reactor at 150°C for 30min, cool, and centrifuge to remove the bottom Sediments, serum is antibacterial lubricant.

[0032] See attached figure 1 , attached figure 2 , attached image 3 And attached Figure 4 The antibacterial figure, the antibacterial lubricant that the processing method described in this embodiment makes has excellent antibacterial property. Figure 5 It is the transmission electron microscope figure of the antibacterial lubricant of the present embodiment, and clustered metal oxides are evenly dispersed in the antibact...

Embodiment 2

[0034] See attached figure 2 , the preparation and application of an antibacterial lubricant for the outer tube of a tampon, dispersing nano-zinc oxide, nano-titanium oxide, cerium nitrate, and cyclodextrin in water according to the molar ratio of 1:0.5:0.01:3.5 to prepare 0.02M water Dispersion A; gradually add 10 ml of aqueous solution A to 100 ml of polyethylene glycol 400B dropwise under stirring to obtain a stable water-in-oil system; put it in a microwave oven, react at 150°C for 20 minutes, cool, and centrifuge. The bottom sediment is removed, and the supernatant is an antibacterial lubricant.

[0035] See attached figure 1 , attached figure 2 , attached image 3 And attached Figure 4 The antibacterial figure, the antibacterial lubricant that the processing method described in this embodiment makes has excellent antibacterial property. Figure 5 It is the transmission electron microscope figure of the antibacterial lubricant of the present embodiment, and cluste...

Embodiment 3

[0037] Preparation and application of an antibacterial lubricant for the outer tube of a tampon. Nano-zinc oxide, nano-magnesium oxide, neodymium nitrate, and lecithin are dispersed in water at a molar ratio of 1:0.5:0.01:3.5 to prepare a 0.05M aqueous dispersion A: Gradually add 10ml of aqueous solution A to 100ml of polyethylene glycol 200B dropwise under stirring to obtain a water-in-oil system; put it in a microwave oven, react at 140°C for 30min, cool, and centrifuge to remove the sediment at the bottom , the serum is an antibacterial lubricant.

[0038] See attachedfigure 1 , attached figure 2 , attached image 3 And attached Figure 4 The antibacterial figure, the antibacterial lubricant that the processing method described in this embodiment makes has excellent antibacterial property. Figure 5 It is the transmission electron microscope figure of the antibacterial lubricant of the present embodiment, and clustered metal oxides are evenly dispersed in the antibacter...

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Abstract

The invention belongs to the field of functional hygienic material preparation and discloses application and preparation of an antibacterial lubricant for tampon outer tubes. The technical scheme includes that mixing antibacterial metal oxide, a small quantity of rare earth mineral elements and a complexing agent according to a certain proportion, and gradually dropwise adding into an oil system under a stirring condition to form a stable water-in-oil system; performing reaction in a reaction kettle for 30-120min at 120-170 DEG C, cooling, and centrifuging to separate and remove precipitates to obtain the antibacterial lubricant. The antibacterial lubricant can be sprayed to the tampon outer tubes to make it convenient for implantation of the tubes, an antibacterial effect is achieved, andthe problem of skin allergy caused by organic antibacterial agents commonly used at present and problems of precipitation and color change caused by inorganic silver ion antibacterial agents are effectively solved. The antibacterial lubricant is capable of removing microorganisms on the outer tubes to improve lubricity, is remarkable in antibacterial function, free of irritation and allergy, safeand environmentally friendly and is capable of effectively overcoming current concerns of out-of-limit microorganisms on the tampon outer tubes.

Description

technical field [0001] The invention discloses the preparation of an antibacterial lubricant and its application on the outer tube of a catheter-type tampon, belonging to the field of preparation of functional sanitary materials. Background technique [0002] Catheter-type tampons are favored by many people because they do not affect clothing and sports during use. European and American women use them more. In the United States, 42% of women use tampons. Because Asians do not like suppositories habitually, tampons are rarely used among women in Asian countries. In China, only 2% of women use tampons. The main reason is that many women use it for the first time. Due to lack of experience or the smoothness of the plastic catheter wall, it is difficult to implant it in the body correctly; secondly, many women think that the tampon and the plastic catheter wall are not hygienic enough, and they are worried that bacteria will be introduced into the uterus. Infection increases th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/50A61L15/46A61L15/18
CPCA61L15/18A61L15/46A61L15/50A61L2300/10A61L2300/102A61L2300/404A61L2300/452A61L2300/622A61L2420/02A61L2420/06
Inventor 郑敏
Owner 苏州宝丽洁医疗科技有限公司