The invention provides a pharmaceutical preparation for treating liver and 
gallbladder damp-heat and a preparation method thereof. The preparation method comprises the following steps: mixing 
potentilla anserine, vervain, lalang grass 
rhizome, radix puerariae, longhairy antenoron 
herb, fiveleaf 
akebia fruit, stir-fried radix paeoniae rubra, 
indigo naturalis, spora lygodii, herba epimedii, 
radix bupleuri, 
bran stir-fried rhizoma atractylodis, 
lavender, endive and liquorice roots in a specific proportion, and carrying out water decoction extraction and 
filtration to obtain an extracting solutionand filter residues; then crushing fried 
coix seeds and purple rice to obtain mixed 
powder, preparing a 
fermentation culture medium from the mixed 
powder and the filter residues, inoculating candidautilis, 
bacillus subtilis and 
geotrichum candidum, performing 
fermentation and 
centrifugation, taking a supernate to obtain 
fermentation liquor, and mixing the fermentation liquor with the extractingsolution to obtain mixed 
powder; adding the mixed powder into a 
hydroxyethyl cellulose-silkworm silk 
fibroin mixed solution, and carrying out uniform 
ultrasonic oscillation and 
drying to obtain an 
inclusion compound; and finally, mixing the 
inclusion compound with auxiliary materials to prepare capsules. Compared with a common 
traditional Chinese medicine decoction, the 
capsule is convenient to take and has a good 
treatment effect on liver and 
gallbladder damp-heat.