Degradable double J tube

A technology of acetone and diisocyanate, which is applied in the field of double J pipes, can solve problems such as environmental impact, difficult to be handled, and difficult aging and decomposition of ordinary polyurethane, and achieve high tensile strength and bending strength, high tensile strength and bending strength, The effect of sustainable development

Inactive Publication Date: 2018-03-23
THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the wide use of double J tubes and the large demand, major manufacturers have produced and manufactured them one after another. However, double J tubes are disposable products, and traditional double J tubes are made of polyurethane polymer materials. Ordinary polyurethane materials are difficult to produce. Aged and decomposed under natural conditions, resulting in a large number of used double J tubes being randomly placed, taking up a lot of space, and it is difficult to be disposed of, and even has a certain impact on the environment, requiring a lot of manpower and material resources can be solved, the economic cost is too high
[0003] In the prior art, the Chinese patent application number CN201010288729.5 is a biodegradable polyurethane and its preparation method. The inventive method is stable and easy to control, and the prepared polyurethane has good biodegradability and other characteristics, which solves the problem of Ordinary polyurethane is difficult to decompose due to aging, and the double J tube prepared by it has good mechanical properties such as tensile strength and elastic modulus; however, since the double J tube is mainly used in urological surgery, it needs to When working in a urine environment, the mechanical properties such as tensile strength will be greatly reduced when the double J tube made of polyurethane is working in a urine environment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: A kind of degradable double J tube, comprises following composition by weight:

[0044] Acetone: 180 parts

[0045] Diphenylmethane diisocyanate: 150 parts

[0046] Polyethylene glycol: 65 parts

[0047] Cornstarch: 70 parts

[0048] Cellulose: 60 parts

[0049] Catechin: 25 servings

[0050] Lignin: 20 parts

[0051] Chain extender: 15 parts

[0052] Coupling agent: 5 parts

[0053] Anti-wear agent: 3 parts

[0054] Conditioner: 6 servings

[0055] Stabilizer: 2 parts

[0056] Hardening agent: 1 part

[0057] Thickener: 1 part

[0058] Catalyst: 3 parts

[0059] 1-methoxy-2-methyl-1-(trimethylsiloxy)propene: 4 parts

[0060] Trimethylsilyl trimethylsilacetate: 3 parts

[0061] 3,3-Trimethylsilyl dimethacrylate: 2 parts

[0062] Ammonium Lactate: 3 parts.

[0063] The chain extender is a mixture of 4-aminobenzamidoethanol and glycerol phosphate, and its mass ratio is 1:1.

[0064] The coupling agent is 3-(acryloyloxy)propyltrimethoxysilane...

Embodiment 2

[0077] Embodiment 2: A kind of degradable double J tube, comprises following composition by weight:

[0078] Acetone: 180 parts

[0079] Diphenylmethane diisocyanate: 150 parts

[0080] Polyethylene glycol: 65 parts

[0081] Cornstarch: 70 parts

[0082] Cellulose: 60 parts

[0083] Catechin: 25 servings

[0084] Lignin: 20 parts

[0085] Chain extender: 15 parts

[0086] Coupling agent: 5 parts

[0087] Anti-wear agent: 3 parts

[0088] Conditioner: 6 servings

[0089] Stabilizer: 2 parts

[0090] Hardening agent: 1 part

[0091] Thickener: 1 part

[0092] Catalyst: 3 parts

[0093] 1-methoxy-2-methyl-1-(trimethylsiloxy)propene: 4 parts

[0094] Trimethylsilyl trimethylsilacetate: 3 parts

[0095] 3,3-Trimethylsilyl dimethacrylate: 2 parts

[0096] Ammonium Lactate: 3 parts.

[0097] The chain extender is 4-aminobenzamidoethanol.

[0098] The coupling agent is 3-(acryloyloxy)propyltrimethoxysilane.

[0099] The anti-wear agent is cetyltrimethoxysilane.

[0...

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PUM

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Abstract

The invention discloses a degradable double J tube. Firstly, methylene diphenyl diisocyanate is completely dissolved in acetone, then polyethylene glycol, corn starch, cellulose, 1-methoxy-2-methyl-1-(trimethylsiloxy) propene, trimethylsilyl trimethylsilyl acetate, trimethylsilyl 3,3-dimethylacrylate, ammonium lactate and a catalyst are added to acetone, and a prepolymer is formed; after completereaction, catechinic acid and lignin are added to a prepolymer solution, a chain extender is added for chain extension again, water washing, alcohol washing and drying are performed, a product obtained after drying and auxiliaries are added to an extruder for extrusion and pelletization, prepared particles are placed in the extruder for extrusion molding, cutting, modification and other treatmentare executed, and a finished product is prepared finally. The prepared double J tube has good degradability and sustainable development is facilitated; the double J tube further has higher tensile strength, bending strength and other mechanical properties, and still has higher tensile strength and bending strength even in the urine environment.

Description

technical field [0001] The invention relates to a double J tube, more specifically to a degradable double J tube. Background technique [0002] Double J tube, known as pigtail catheter or ureteral stent tube or D-J tube, is often used in urological surgery, suitable for kidney stones, ureteral stones, hydronephrosis, kidney transplantation, benign tumors of the kidney and ureter, etc. During the treatment of upper urinary tract surgery, lithotripsy, and dilation of ureteral stricture, it can play an important role in draining urine and preventing ureteral stricture and adhesion blockage after being implanted in the ureter. Due to the wide use of double J tubes and the large demand, major manufacturers have produced and manufactured them one after another. However, double J tubes are disposable products, and traditional double J tubes are made of polyurethane polymer materials. Ordinary polyurethane materials are difficult to produce. Aged and decomposed under natural condit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08G18/48C08G18/76C08L75/08C08L3/02C08L1/02C08L1/28C08K5/5425C08K5/5419C08K5/098
CPCC08G18/4825C08G18/4833C08G18/7671C08L75/08C08L2203/02C08L2203/18C08L2205/02C08L2205/035C08L3/02C08L1/02C08L1/284C08K5/5425C08K5/5419C08K5/098
Inventor 何国荣林孝坤陈聪德刘平张华赵一鸣李仲荣李育梅胡小叶
Owner THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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