Liquid crystal transdermal absorption promoter and preparation method thereof, and uses of liquid crystal transdermal absorption promoter in anti-aging cosmetics

An anti-aging and cosmetics technology, applied in anti-aging cosmetics, in the field of liquid crystal transdermal absorbents, can solve the problems affecting the effective absorption and efficacy of anti-aging cosmetics, limiting the diffusion and penetration of active polypeptides, and the high price of active polypeptides , to achieve the effect of enhancing skin luster and transparency, skin feeling mild, refreshing and non-irritating, and achieving transdermal absorption

Inactive Publication Date: 2018-09-07
上海智芙科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, due to the high price and poor stability of active peptides, it is difficult to add a large amount of them in anti-aging cosmetics, and it is impossible to form a high concentration gradient inside and outside the skin, which ultimately limits the diffusion and impact of active peptides on the skin in anti-aging skin care cosmetics. Penetration, which affects the effective absorption and efficacy realization of anti-aging cosmetics containing active peptides
[0010] However, traditional transdermal absorbents are mainly used in the pharmaceutical industry, and the negative problems such as inconvenient use, sticky and greasy skin feeling, strong skin irritation, and many allergic reactions have not been well resolved.

Method used

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  • Liquid crystal transdermal absorption promoter and preparation method thereof, and uses of liquid crystal transdermal absorption promoter in anti-aging cosmetics
  • Liquid crystal transdermal absorption promoter and preparation method thereof, and uses of liquid crystal transdermal absorption promoter in anti-aging cosmetics

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Embodiment 1

[0031]Example 1 provides a liquid crystal transdermal absorption enhancer and its preparation method. The dosage (wt%) and components of the liquid crystal transdermal absorption enhancer are shown in Table 1.

[0032] Its preparation process is as follows:

[0033] (1) Accurately weigh the various raw materials in the formula and store them in clean and sterilized containers;

[0034] (2) After cleaning and sterilizing the vacuum emulsification pot, add the raw materials of phase A into the vacuum emulsification pot, stir well and heat up to 70-75°C; after completely dissolving, turn on cooling water to cool down, and when the temperature drops below 60°C Add phase B, homogenize and stir thoroughly.

[0035] (3) Cool down to below 50°C and add phase C, stir well and then discharge.

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Abstract

The present invention provides a liquid crystal transdermal absorption promoter and a preparation method thereof, and uses of the liquid crystal transdermal absorption promoter in anti-aging cosmetics, wherein the liquid crystal transdermal absorption promoter comprises, by weight, 1-20 parts of phytosterol / octyldodecyl lauroyl glutamate, 1-20 parts of arachidyl glucoside, 1-30 parts of Isononyl Isononanoate, 1-30 parts of cetearyl alcohol, 1-30 parts of shea butter, 1-50 parts of butanediol, and 50-90 parts of water. According to the present invention, the polypeptide anti-aging cosmetic prepared through the transdermal absorption promoter is the oil-in-water cosmetic, and has characteristics of good stability, good affinity to skin, mild skin feeling, refreshing and no irritation; and the skin clinical trial results show that the composition can effectively promote the transdermal absorption of the active polypeptide in the anti-aging cosmetic, and can promote the active polypeptideto well provide the skin care effects of significantly facial wrinkle reducing, smooth and firm skin restoring and skin gloss and transparency enhancing.

Description

technical field [0001] The invention relates to the technical field of cosmetics preparation, in particular to a liquid crystal transdermal absorbent, its preparation and its application in anti-aging cosmetics. Background technique [0002] The stratum corneum of human skin is the outermost layer of the epidermis, composed of 4 to 8 layers of dead flat lamellar anuclear cells. Among them, keratinocytes and intercellular lipids form a "brick wall structure", where the "brick wall" represents keratinocytes, which are composed of keratin, non-fibrous protein and a small amount of lipid; while the "mortar" between the brick walls is Refers to skin lipids with a special structure of bilayers in the space between keratinocytes. [0003] The stratum corneum can protect the skin, prevent the extravasation of tissue fluid in the body, and limit the barrier function of the stratum corneum of water, lipids or cosmetic ingredients. The stratum corneum hinders the transdermal penetrati...

Claims

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Application Information

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IPC IPC(8): A61K8/63A61K8/60A61K8/37A61K8/34A61K8/92A61K8/02A61K8/64A61Q19/08
CPCA61K8/0295A61K8/342A61K8/345A61K8/37A61K8/602A61K8/63A61K8/64A61K8/922A61Q19/08
Inventor 华彦俊
Owner 上海智芙科技有限公司
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