A kind of preparation method and application of argan oil microemulsion spray

A technology of microemulsion spray and nut oil, which is applied in the directions of aerosol delivery, anti-inflammatory agent, pharmaceutical formulation, etc., can solve the problem that macadamia nut oil and green bark extract cannot be mutually miscible and used synergistically, and green bark by-products cannot be effectively utilized, Nut oil is easy to oxidize and other problems, to achieve the effect of improving economic added value, simple preparation method and overcoming easy oxidation

Active Publication Date: 2021-03-23
SOUTH SUBTROPICAL CROPS RES INST CHINESE ACAD OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In order to achieve the above object, the present invention provides a preparation method of macadamia nut oil microemulsion spray, which solves the problem that macadamia nut oil and green bark extract cannot be miscible and coordinated, and effectively solves the problem that macadamia nut oil is easily oxidized, insoluble in water, It is difficult to be widely used in the fields of medicine and cosmetics; at the same time, it solves the problem that a large number of green skin by-products produced in the processing of macadamia nuts cannot be effectively utilized, and improves the economic added value of macadamia nut oil and by-products

Method used

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  • A kind of preparation method and application of argan oil microemulsion spray

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Embodiment 1

[0023] Embodiment 1 adopts the following steps to realize the present invention:

[0024] (1) Preparation of argan oil nano-microemulsion: Mix Tween 60 and hydrogenated castor oil (mass ratio 2.5:1) as a composite surfactant, and cosurfactant polyethylene glycol and argan oil (mass ratio 1:3.5 ) as a mixed oil phase, and then mix the two at a mass ratio (1:1) to form an emulsion, stir evenly with magnetic force (rotation speed 1200rpm) at 55~70°C, and add distilled water (8 times the mass of the emulsion) dropwise High-speed shear dispersion to obtain W / O nano-emulsion, and then homogenize through a high-pressure micro-fluidic homogenizer (homogenization pressure 50MPa) for 3 times until a transparent and clear nano-emulsion is formed;

[0025] (2) Preparation of macadamia nut green peel extract: take macadamia nut green peel powder with a particle size of 100 mesh and 8 times the mass of macadamia nut green peel powder with a volume fraction of 70% edible alcohol, mix them, a...

Embodiment 2

[0027] Embodiment 2 adopts the following steps to realize the present invention:

[0028] (1) Preparation of argan oil nano-microemulsion: Mix Tween 60 and hydrogenated castor oil (mass ratio 2.5:1) as a composite surfactant, and cosurfactant polyethylene glycol and argan oil (mass ratio 1:3.5 ) as a mixed oil phase, and then mix the two at a mass ratio (1:1) to form an emulsion, stir evenly with magnetic force (rotation speed 1200rpm) at 55~70°C, and add distilled water (10 times the mass of the emulsion) dropwise High-speed shear dispersion to obtain W / O nano-emulsion, and then homogenized by a high-pressure micro-fluidic homogenizer (homogenization pressure 60MPa) 4 times until a transparent and clear nano-emulsion is formed;

[0029] (2) Preparation of macadamia nut green peel extract: take macadamia nut green peel powder with a particle size of 100 mesh and 6 times the mass of macadamia nut green peel powder with a volume fraction of 70% edible alcohol, mix them, and extr...

Embodiment 3

[0031] Embodiment 3 Adopt the following steps to realize the present invention:

[0032] (1) Preparation of argan oil nano-microemulsion: Mix Tween 60 and hydrogenated castor oil (mass ratio 2.5:1) as a composite surfactant, and cosurfactant polyethylene glycol and argan oil (mass ratio 1:3.5 ) as a mixed oil phase, and then mix the two at a mass ratio (2:1) to form an emulsion, stir evenly with magnetic force (rotation speed 1200rpm) at 55~70°C, and add distilled water (12 times the mass of the emulsion) dropwise High-speed shear dispersion to obtain W / O nano-emulsion, and then homogenized by a high-pressure micro-jet homogenizer (homogeneous pressure 80MPa) for 3 to 5 times until a transparent and clear nano-emulsion is formed;

[0033](2) Preparation of macadamia nut green peel extract: take macadamia nut green peel powder with a particle size of 200 mesh and 10 times the mass of macadamia nut green peel powder with a volume fraction of 70% edible alcohol, mix them, and ext...

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Abstract

The invention discloses a preparation method and application of a nut oil micro-emulsion spray. When the nut oil micro-emulsion spray is prepared, firstly, Tween-60 and hydrogenated castor oil serve as a composite surfactant, polyethylene glycol and nut oil serve as a mixed oil phase, nut oil nano micro-emulsion is prepared, then a macadimia nut green husk extracting solution and the nut oil nanomicro-emulsion are mixed, high-speed shearing dispersion and filtration are carried out, 95% edible alcohol, menthol and / or borneol are added, finally, the material is degermed and filtered, a spray bottle is filled with the material, and the spray is obtained. According to the nut oil micro-emulsion spray, the excellent characteristics of macadimia nut green husks and the macadimia nut oil are combined and exerted, the spray has a remarkable effect especially on the aspect of inflammation diminishing, and the nut oil micro-emulsion spray has broad application prospects on the aspect of inflammation diminishing and itching relieving. The preparation method of the nut oil micro-emulsion spray is simple and convenient to operate, and industrialized production is easy to achieve.

Description

technical field [0001] The invention belongs to the technical field of processing microemulsion medicines and cosmetics, and in particular relates to a preparation method and application of a macadamia nut oil microemulsion spray. Background technique [0002] Macadamia (Macadamia integrifolia) , also known as macadamia nuts, Australian walnuts, etc., belongs to the family Proteaceae (Proteaceae), and the genus Macadamia ( Macadamia F. Muell) perennial evergreen arbor fruit tree, native to the subtropical rainforest of Australia, is known as the "Queen of Dried Fruits" because of its unique nut flavor and rich nutrition. The kernels of macadamia nuts contain a large amount of tocopherol and squalene. The kernels contain nearly 80% oil, and almost 80% of the fatty acids are monounsaturated fatty acids, and oleic acid (60%) and palmitoleic acid (20%) are the main components. host. Refined macadamia nut oil has a light yellow color and less strong smell than virgin olive oi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61K9/12A61K9/107A61K8/9789A61K8/92A61K8/06A61K8/04A61K47/10A61P17/02A61P17/00A61P17/16A61P29/00A61P17/04A61Q19/00
CPCA61K8/046A61K8/062A61K8/922A61K9/1075A61K9/12A61K36/185A61K47/10A61Q19/00A61K8/9789A61P17/00A61P17/02A61P17/04A61P17/16A61P29/00A61K2300/00
Inventor 涂行浩杜丽清张帅中曾辉帅希祥张明马飞跃
Owner SOUTH SUBTROPICAL CROPS RES INST CHINESE ACAD OF TROPICAL AGRI SCI
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