A kind of preparation method of broken wall decoction pieces of palm ginseng

A technology of broken wall decoction pieces and palm ginseng, which is applied in the field of medicine, can solve the problems of inability to ensure that the microbial content of the product reaches the standard, the sterilization process is cumbersome, and the time cost is high. Effect

Active Publication Date: 2022-01-11
GUANGZHOU HANFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The sterilization process of this method is cumbersome, time-consuming, and time-costly, and after the coarse powder is sterilized, it is easily contaminated by microorganisms such as bacteria and mold in the subsequent operation process, and it cannot ensure that the microbial content of the granulated product reaches the standard

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] An embodiment of the preparation method of the broken wall decoction pieces of ginseng palm of the present invention comprises the following steps:

[0028] (1) Steam explosion treatment of medicinal materials: 5 kg of fresh ginseng palm medicinal materials are washed with water to wash the impurities on the surface, placed to drain the surface moisture, and then crushed into coarse slag of ginseng palm by steam explosion technology (the pressure of steam explosion is 1.2MPa, ginseng palm The water content is 10%, and the time to maintain the pressure is 1.0min);

[0029] (2) Wall breaking: the coarse slag was dried under reduced pressure at 45° C. for 3 hours to make the moisture reach about 10%, and the coarse slag of Ginseng palm was broken and pulverized by a micro-powder machine under low temperature circulation conditions. The pulverization time was 20 minutes, and the broken wall was pulverized to For ultra-fine powders of more than 300 meshes, routinely detect t...

Embodiment 2

[0033] An embodiment of the preparation method of the broken wall decoction pieces of ginseng palm of the present invention comprises the following steps:

[0034] (1) Steam explosion treatment of medicinal materials: 5 kg of fresh palm ginseng medicinal materials are washed with water to wash the impurities on the surface, placed to drain the water on the surface, and then crushed into coarse slag of palm ginseng by steam explosion technology (the pressure of steam explosion is 1.8 MPa, ginseng palm The water content is 80%, and the time to maintain the pressure is 10 minutes);

[0035] (2) Wall breaking: put the coarse slag in a freeze-drying box and cool it down to -35°C, keep it for 3 hours for freeze-drying, vacuumize the system until the absolute pressure of the system is 50Pa, start heating to 50°C, and sublimate and dry for 3 hours. The water content reaches about 5%; the coarse slag of palm ginseng is crushed with a micro-powder machine under low-temperature circulati...

Embodiment 3

[0039] An embodiment of the preparation method of the broken wall decoction pieces of ginseng palm of the present invention comprises the following steps:

[0040] (1) Steam explosion treatment of medicinal materials: 5 kg of fresh palm ginseng medicinal materials are washed with water to clean the surface impurities, placed to drain the surface moisture, and then crushed into palm ginseng coarse residue by steam explosion technology (the pressure of steam explosion is 1.5MPa, palm ginseng The water content is 50%, and the time to maintain the pressure is 5 minutes);

[0041] (2) Wall breaking: Put the crude ginseng residue in a freeze-drying oven to cool down to -35°C, keep it for 5 hours for freeze-drying, vacuumize the system until the absolute pressure of the system is 50Pa, start heating to 50°C, and sublimate and dry for 3 hours , so that the water content is less than 5%; the coarse slag of palm ginseng is broken and pulverized by a micro-powder machine under low-temperat...

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Abstract

The invention relates to a preparation method of broken-wall decoction pieces of ginseng palm, belonging to the technical field of medicine. The preparation method of the broken-wall decoction pieces of ginseng palm of the present invention comprises the following steps: (1) crushing ginseng palm into coarse slag through steam explosion technology; (2) drying the coarse slag, and then crushing the ginseng palm into ultrafine powder by ultrafine pulverization technology , taking the parenchyma cells as the index characteristic cells to determine the wall-breaking rate of the palm ginseng ultrafine powder, and obtain the ultrafine powder with the wall-breaking rate up to standard; (3) granulate the ultrafine powder with a solvent, dry, granulate, Packed separately, you can get the broken pieces of palm ginseng. The broken-wall decoction pieces of palm ginseng prepared by the method of the present invention have good particle shape, easy drying, moderate elasticity, good solubility in water, clear index of wall-breaking rate, high wall-breaking rate, high retention rate and dissolution rate of medicinal components 1. The utilization rate of medicinal materials is high, and the microbial limit of the obtained product is easy to control, which can ensure the safety and effectiveness of medication.

Description

technical field [0001] The invention relates to a preparation method of broken-wall decoction pieces of ginseng palm, belonging to the technical field of medicine. Background technique [0002] Palm ginseng (Gymnadenia conopsea (L.) R.Br.), also known as hand ginseng, palm ginseng, hand ginseng, and Bergamot ginseng, is the root of the orchid plant Gymnadenia conopsea (L.) R.Br., which is a rare plant growing on the Qinghai-Tibet Plateau. The medicinal material grows in the alpine shrubs at an altitude of 3000-4000 meters. It is named for its shape like a palm. It has the effects of nourishing essence, promoting essence and quenching thirst, and is often used in powder form. It is an important drug in Tibetan medicine and a single medicinal material in many Tibetan medicine formulas, such as "Bushen Pill" recorded in the National Tibetan Medicine Standard Book ", "Shiwei Shoushen Powder", "Shibawei Dangshen Pills" and other Tibetan medicine compound prescriptions are all us...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61K9/16
CPCA61K36/898A61K2236/17A61K2236/15
Inventor 袁诚龙海林蔡鸿飞张懿李康强潘裕清李海波杨阳许文东蒋兆健
Owner GUANGZHOU HANFANG PHARMA
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