Analgesic and detumescence plaster, and preparation method and application thereof

A technology for relieving pain, reducing swelling, and plastering. It is applied in the direction of non-central analgesics, pharmaceutical formulas, and medical preparations containing active ingredients. It can solve problems such as unbalanced drug effects, poor therapeutic effects, and inability to persist in use.

Inactive Publication Date: 2020-02-04
FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The traditional Chinese medicine plaster for treating joint diseases in the prior art lacks effective ingredients in the prescription, resulting in a single treatment or a low cure rate; at the same time, the efficacy of the medicine in the prescription cannot be brought into full play as soon as possible, or the efficacy of the medicine is not brought into full play. Balanced, Poor Healing Effect
Simultaneously existing traditional Chinese medicine sticking plaster often can cause irritation to the attached skin when being used, so that the phenomenon of allergy and itching is arranged on the attached skin
It is very likely that patients will not be able to insist on using this plaster
The existing treatment methods all have long treatment time and poor treatment effect, which have a bad impact on the patient's body and mind. Nowadays, people pay more and more attention to joint diseases, and the development of drugs with short treatment time and good treatment effect It has also become a hot spot and an urgent problem to be solved

Method used

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  • Analgesic and detumescence plaster, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Example 1 A method for preparing an analgesic and detumescent plaster.

[0059]A plaster for relieving pain and reducing swelling, said plaster is formed by mixing ointment A and powder B, said ointment A part includes the following raw materials in parts by weight: 20 parts of Fangji, 20 parts of Guizhi, 30 parts of Duhuo, Asarum 10 parts, 50 parts of Aconitum, 50 parts of Aconitum, 30 parts of Chuanjiao, 50 parts of Aconite, 90 parts of Araceae, 60 parts of turmeric, 30 parts of peach kernel, 40 parts of angelica, 20 parts of frankincense, 20 parts of myrrh; and press One or more of the following raw materials are also added in parts by weight: 20-50 parts of ginger, 20-50 parts of Gynostemma pentaphyllum, 20-50 parts of Sperancus, 20-50 parts of Schizonepeta, 20-50 parts of silkworm excrement 20-50 parts of Shenjincao, 20-50 parts of mulberry branch, 20-50 parts of loofah, 20-50 parts of salvia miltiorrhiza, 20-50 parts of safflower, 20-50 parts of peach kernel, 20-5...

Embodiment 2

[0067] Embodiment 2 clinical experiment.

[0068] 1. Materials and methods.

[0069] 1.1 General Information.

[0070] From May 2017 to May 2019, there were 210 patients with rheumatoid arthritis (bi syndrome diagnosed by traditional Chinese medicine) in the outpatient and ward of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, 85 males and 125 females; the oldest was 80 years old and the youngest was 16 years old. years old, with an average of 53.3 years; the longest course of disease was 33 years, the shortest was 1.8 months, and the average course of disease was 8.34 years. They were randomly divided into three groups according to the order of treatment: 70 cases in the treatment group, 70 cases in the control group A, and 70 cases in the control group B. For example, there was no significant difference (P>0.05) among the three groups in terms of age, gender, and course of disease, and they were comparable.

[0071] 1.2 Inclusion and exclus...

Embodiment 3

[0093] Example 3 Typical case.

[0094] 1. Rheumatoid arthritis.

[0095] Symptoms: swelling and pain in both knee joints, obvious in the morning, aggravated after exercise.

[0096] Clinical diagnosis: rheumatoid arthritis.

[0097] Clinical manifestations: swelling and pain of both knee joints, aggravated by activities.

[0098] Adverse consequences achieved: Affect daily walking activities and require human care.

[0099] Medication: The part A of the ointment is made of the following raw materials in parts by weight: 20 parts of Fangji, 20 parts of Guizhi, 30 parts of Duhuo, 10 parts of Asarum, 50 parts of Aconitum Aconitum, 50 parts of Aconitum Aconitum, 30 parts of Chuanjiao, 50 parts of aconite, 90 parts of Araceae, 60 parts of turmeric, 30 parts of peach kernel, 40 parts of angelica, 20 parts of frankincense, and 20 parts of myrrh; the part B of the powder is made of the following raw materials in parts by weight: 10 parts of white mustard seed, 20 parts of ground ...

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Abstract

The invention relates to the field of external application of traditional Chinese medicine preparations, in particular to an analgesic detumescence plaster, a preparation method and application thereof. The analgesic detumescence plaster is prepared by mixing a medicinal extract A and powder B, the medicinal extract A is prepared from the following bulk pharmaceutical chemicals in parts by weight:20-90 parts of stephania terandra, 20-90 parts of cassia twig, 20-90 parts of radix angelicae pubescentis, 20-90 parts of herba asari, 20-90 parts of radix aconiti, 20-90 parts of radix aconiti agrestis, 20-90 parts of pericarpium zanthoxyli, 20-90 parts of radix aconiti lateralis preparata, 20-90 parts of rhizoma arisaematis, 20-90 parts of rhizoma curcumae longae, 20-90 parts of peach kernels,20-90 parts of angelica sinensis, 20-90 parts of olibanum and 20-90 parts of myrrh; and the powder B is prepared from the following bulk pharmaceutical chemicals in parts by weight: 6-20 parts of semen brassicae, 6-20 parts of ground beeltle, 6-20 parts of pseudo-ginseng, 6-20 parts of the olibanum, 6-20 parts of the myrrh and 6-20 parts of the pericarpium zanthoxyli. The analgesic detumescence plaster is used for treating rheumatoid arthritis, osteoproliferation, synovitis, lumbar intervertebral disc prolapse and various joint pain and swelling, the analgesic and detumescence effects are good, operation is easy, carrying is convenient, toxic side effects are avoided, the pesticide effect of a composition traditional Chinese medicine material is proportionately developed, the medicine utilization is high, and the treatment effect is good.

Description

technical field [0001] The invention relates to the field of externally applied traditional Chinese medicine preparations, in particular to a traditional Chinese medicine plaster for treating rheumatoid arthritis, in particular to an analgesic and swelling plaster and a preparation method and application thereof. Background technique [0002] Plaster external application (to achieve swelling and pain relief) has a long history of therapy, which has long been found in the "Behind the Elbow" of the Jin Dynasty. painted back". "Taiping Shenghui Fang" in the Song Dynasty has "to treat windy waist and feet, cold pain and wind, three peeled navels of Aconitum aconitum, powdered, coated with silk, and stopped in a moment." The "Puji Prescription" of the Ming Dynasty has "nasal sinus and brain diarrhea, raw aconite powder, green onion saliva and mud, Fuyongquan point". Li Shizhen's "Compendium of Materia Medica" in the Ming Dynasty stated that "mash the red root, enter the yuan in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K36/9068A61K9/70A61P29/00A61P19/02A61P19/08A61P19/04A61K35/64A61K35/32A61K35/60A61K35/62A61K35/646A61K35/648
CPCA61K9/7023A61K35/32A61K35/60A61K35/62A61K35/64A61K35/646A61K35/648A61K36/11A61K36/12A61K36/185A61K36/21A61K36/232A61K36/234A61K36/238A61K36/254A61K36/258A61K36/264A61K36/268A61K36/284A61K36/286A61K36/31A61K36/324A61K36/328A61K36/42A61K36/424A61K36/47A61K36/481A61K36/484A61K36/486A61K36/487A61K36/489A61K36/515A61K36/537A61K36/538A61K36/54A61K36/59A61K36/605A61K36/638A61K36/65A61K36/68A61K36/69A61K36/704A61K36/71A61K36/714A61K36/736A61K36/74A61K36/75A61K36/752A61K36/756A61K36/758A61K36/804A61K36/815A61K36/884A61K36/8884A61K36/8905A61K36/8945A61K36/9066A61K36/9068A61K2236/331A61K2236/39A61K2236/51A61P19/02A61P19/04A61P19/08A61P29/00A61K2300/00
Inventor 王春波薛书燕姜兆荣王玲王丹王琳王晶刘海云曹明卓蒋学斯高帅
Owner FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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