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Rhizoma polygonati polypeptide composite tablet and preparation method thereof

A compound tablet and sealwort technology, applied in the field of Polygonatum Polypeptide Compound Tablet and its preparation, can solve the problems of unreported processing technology, limited plant protein extraction ability, loss of medicinal ingredients, etc., to achieve easy absorption, accelerated disintegration speed, good effect

Active Publication Date: 2020-03-31
西藏天虹科技股份有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the sealworts on the market are processed products, and the effective ingredients in the sealwort are generally extracted by decocting. This method has a limited ability to extract the plant protein in the effective ingredients, which will cause a large loss of effective ingredients.
And the common Polygonatum products on the market are mainly Polygonatum decoction pieces, Polygonatum pills, Polygonatum wine, etc. that are produced by extraction, and Polygonatum polypeptide composite tablets made from Polygonatum as the main raw material and its processing technology have not been reported yet

Method used

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  • Rhizoma polygonati polypeptide composite tablet and preparation method thereof
  • Rhizoma polygonati polypeptide composite tablet and preparation method thereof
  • Rhizoma polygonati polypeptide composite tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A Polygonatum Polypeptide Composite Tablet comprises the following raw materials: 40g of Polygonatum Polypeptide, 20g of Ovalbumin, 7g of Yeast Extract, 1g of Zinc Stearate, and 10g of Maltitol.

[0027] Wherein, the preparation method of the Polygonatum Polypeptide comprises:

[0028] Step 1, dry the slices of Rhizoma Polygonatum and make it into powder, add the ethanol solution with a volume fraction of 40% according to the ratio of material to liquid of 1:45g / ml, heat and reflux in a water bath to extract for 35min, the temperature of the water bath is 50°C, and then filter the ethanol solution to obtain Filtrate and filter residue, the filter residue was added to the CO 2 In the expansion solvent composed of ethanol, pressurize 1.5MPa to form an expansion system, ultrasonically extract at room temperature for 20min, the ultrasonic frequency is 30kHz, release the pressure after extraction, filter to obtain the extract, combine the filtrate and extract, and then reduc...

Embodiment 2

[0037] A Polygonatum Polypeptide Composite Tablet comprises the following raw materials: 55g of Polygonatum Polypeptide, 30g of Ovalbumin, 15g of Yeast Extract, 3g of Zinc Stearate, and 20g of Maltitol.

[0038] Wherein, the preparation method of the Polygonatum Polypeptide comprises:

[0039] Step 1: Dried Polygonatum slices and made into powder, adding 50% ethanol solution with a volume fraction of 1:50g / ml according to the ratio of material to liquid, heating and refluxing in a water bath for extraction for 45min, the temperature of the water bath was 60°C, and then filtering the ethanol solution to obtain Filtrate and filter residue, the filter residue was added to the CO 2 In the expansion solvent composed of alcohol and ethanol, pressurize 2.5MPa to form an expansion system, ultrasonically extract at room temperature for 25min, the ultrasonic frequency is 35kHz, release the pressure after extraction, filter to obtain the extract, combine the filtrate and extract, and the...

Embodiment 3

[0048] A Polygonatum Polypeptide Composite Tablet comprises the following raw materials: 48g of Polygonatum Polypeptide, 26g of Ovalbumin, 11g of Yeast Extract, 2g of Zinc Stearate, and 14g of Maltitol.

[0049] Wherein, the preparation method of the Polygonatum Polypeptide comprises:

[0050] Step 1: Dried Polygonatum slices and made into powder, adding 45% ethanol solution with a volume fraction of 1:47g / ml according to the ratio of material to liquid, heating and refluxing in a water bath for extraction for 40min, the temperature of the water bath was 55°C, and then filtering the ethanol solution to obtain Filtrate and filter residue, the filter residue was added to the CO 2 In the expansion solvent composed of ethanol, pressurize 2MPa to form an expansion system, conduct ultrasonic extraction at room temperature for 23min, the ultrasonic frequency is 33kHz, release the pressure after extraction, filter to obtain the extract, combine the filtrate and extract, and then decom...

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Abstract

The invention discloses a rhizoma polygonati polypeptide composite tablet which comprises the following raw materials, by weight: 40 to 55 parts of rhizoma polygonati polypeptide, 20 to 30 parts of ovalbumin, 7 to 15 parts of yeast extract, 1 to 3 parts of zinc stearate and 10 to 20 parts of maltitol. The invention also provides a preparation method of the rhizoma polygonati polypeptide compositetablet. The rhizoma polygonati polypeptide is obtained by enzymolysis of specific protease, the ovalbumin is processed by enzymolysis with a specific enzyme to obtain a glucoside chain attached to theovalbumin, and the rhizoma polygonati polypeptide and the glucoside chain are compounded under the catalytic action of a biological enzyme to form the rhizoma polygonati polypeptide composite tabletwith a blood fat reducing effect. Since the polypeptide molecular weight is small and can be easily absorbed by a human body, so that the rhizoma polygonati polypeptide composite tablet is good in effect. In addition, on the basis of a special tablet structure, the disintegration speed of the tablet is increased and the blood concentration can be quickly reached with easy polypeptide absorption.

Description

technical field [0001] The present invention relates to. More specifically, the present invention relates to a Polygonatum Polypeptide Composite Tablet and a preparation method thereof. Background technique [0002] Polygonatum has another name: chicken head Polygonatum, yellow chicken dish, pen tube vegetable, claw ginseng, tiger ginger, chicken claw ginseng, Polygonatum is a plant of the genus Polygonatum, with rhizomes running horizontally, cylindrical, nodules are enlarged, leaf whorls, sessile, for The medicinal and edible plants have the functions of nourishing the spleen, nourishing the lungs and promoting body fluid. However, Polygonatum Polygonatum on the market is mostly a processed product, and the method of decocting is generally used to extract the medicinal ingredients in Polygonatum Rhizoma Polygonatum. This method has limited ability to extract plant protein in the medicinal ingredients, which will cause the loss of a large amount of medicinal ingredients. ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K47/42A61K47/26A61K47/46A61K38/01A61P3/06C12P21/06C07K1/107
CPCA61K9/2013A61K9/2063A61K9/2068A61K38/011A61P3/06C07K1/1077C12P21/06
Inventor 张春颖
Owner 西藏天虹科技股份有限责任公司