Composition for regulating micro-ecology of scalp

A technology of composition and extract, applied in the field of compositions for regulating scalp microecology, can solve the problems of hair depigmentation, increased hair loss, inability to add live probiotics and the like

Active Publication Date: 2020-04-17
广州妮趣化妆品有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antibiotic anti-dandruff agents have a better anti-dandruff effect, but long-term use will make Malassezia resistant, and such anti-dandruff agents will lose their effect over time
The second category is scalp cell growth inhibitors. By inhibiting cell replication, cells can be restored to normal regeneration cycle length, thereby improving dandruff problems. The common drug is selenium disulfide. Many clinical trials have shown that this type of drug is not very effective. Good control of clinical symptoms of dandruff; and its main ingredients are highly irritating, and the hair feels rough after use. If the rinse is not thorough, the hair may be discolored, and a small number of users will increase hair loss, and there are also problems such as odor
Among them, the transportation and preservation of oral preparations is difficult to solve well. The active substances of the preparations, such as lactobacillus and bifidobacteria, need to be stored at low temperature. The harsh storage and use conditions greatly reduce the practicability of oral preparations.
In addition, according to the relevant laws and regulations of cosmetics, live probiotic bacteria cannot be added to cosmetics, but only adding probiotic lysate, relying on the secretion of probiotic bacteria such as antibacterial peptides to play a sterilizing role cannot be a long-term measure

Method used

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  • Composition for regulating micro-ecology of scalp
  • Composition for regulating micro-ecology of scalp
  • Composition for regulating micro-ecology of scalp

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Conditioning shampoo compositions 1-10 formulations are shown in Table 1.

[0078] Table 1

[0079]

[0080]

[0081] Preparation method: Take an appropriate amount of water into the reaction kettle, add EDTA-2Na and stir to dissolve, slowly add polyquaternium-10, start to heat up after the addition, and finally maintain the temperature at 80°C to 85°C, wait for polyquaternium-10 After -10 is completely dissolved, add Sodium Cocoyl Methyl Taurate, Sodium Lauroyl Isethionate, Cocamidopropyl Betaine, Lauryl Hydroxysultaine, Cocamidomethyl MEA, Coconut Oil Amide MEA, citric acid, and sodium citrate. After the system is completely dispersed and uniform, start to cool down. When the temperature drops to 50°C to 55°C, add hexamidine bis(isethionate) salt, Lactobacillus / soybean milk fermentation product filtrate , inulin, flavors, preservatives and continue stirring to ensure all ingredients are well mixed. After adding all the components, viscosity regulator and acid-...

Embodiment 2

[0083] The formulations of care shampoo compositions 11-24 are shown in Table 2.

[0084] Table 2

[0085]

[0086]

[0087] Preparation method: Take an appropriate amount of water into the reaction kettle, add EDTA-2Na and stir to dissolve, slowly add cationic guar gum, start to heat up after the addition is complete, and finally maintain the temperature at 80°C to 85°C, until the cationic guar gum is completely dissolved After that, add Sodium Cocoyl Methylalanine, Sodium Alpha Olefin Sulfonate, Cocamidopropyl Betaine, Sodium Lauroamphoacetate, Cocamidomethyl MEA, Cocamidopropyl PG-Di Methylammonium Chloride, Citric Acid, Sodium Citrate, Polyquaternium-53. After the system is completely dispersed and uniform, start to cool down. When the temperature drops to 50°C to 55°C, add piroctone olamine salt, Lactobacillus / soybean milk fermentation product filtrate, inulin, essence, and preservatives and continue stirring to ensure that all components are well mixed. After ad...

Embodiment 3

[0103] Embodiment 3 efficacy evaluation

[0104] Compositions 1-10 of Example 1 and Compositions 11-24 of Example 2 passed clinical tests and physical and chemical index tests.

[0105] The above-mentioned clinical test refers to: the above-mentioned embodiments 1-24 were given to 24 testers who were troubled by dandruff respectively. The codes of the 24 testers correspond to compositions 1-24.

[0106] The requirements for these testers are: 1) aged between 18 and 40 years old; 2) no perm and dyed hair in the past two months; 3) moderate or above scalp itching; 4) oily scalp; Drugs to inhibit dandruff; 6) Not sensitive to commonly used cosmetics; 7) Have not participated in other clinical tests in the past month; 8) The length of hair on the top of the head is not shorter than 2cm.

[0107] Before the start of the test, the testers used ordinary shampoo (non-oil control anti-dandruff series) to clean their hair four times, once every two days, and then started the test. Th...

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Abstract

The invention belongs to the field of cosmetics, and particularly relates to a composition for adjusting the micro-ecology of the scalp. The composition comprises the following components: a lactobacillus/soybean milk fermentation product filtrate, a chicory extract and an Agave tequilana leaf extract. A shampoo prepared from the composition disclosed by the invention can achieve the effects of maintaining a skin barrier, recovering healthy scalp and remarkably and continuously improving serious grease secretion, dandruff and itching in the head by adjusting the flora environment of the scalp.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a composition for regulating scalp microecology. Background technique [0002] Scalp pityriasis, commonly known as dandruff, manifests as an abnormal increase in flaky white scales that are visible to the naked eye. Usually, skin desquamation is scales that are difficult to observe with the naked eye. When a large number of these scales gather together, dandruff will appear. At present, it is generally believed that the most important cause of dandruff is the colonization of Malassezia. Studies have shown that the number of Malassezia living on the scalp of dandruff patients is the total amount of Malassezia living on the scalp of normal people. 1.5-2 times. The scalp microbial flora mainly includes Staphylococcus, Propionibacterium and Malassezia, these microorganisms together with the scalp environment constitute the scalp microecology. The excessive reproduction of Malas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/9794A61K8/9789A61K8/73A61K8/46A61K8/44A61Q5/00A61Q5/02A61P17/04
CPCA61K8/99A61K8/9794A61K8/9789A61K8/73A61K8/466A61K8/442A61K8/44A61Q5/006A61Q5/02A61Q5/008A61P17/04
Inventor 汤仲标李洪海刘雄健向琴张青周雪怡
Owner 广州妮趣化妆品有限公司
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