Method for controlling growth of microorganisms and/or biofilms in an industrial process

A biofilm and microbial technology, applied in the direction of adding anti-biological reagents, adding sludge control agents, preventing corrosion/sediment formation of pulping equipment, etc.

Active Publication Date: 2020-04-21
KEMIRA OY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Despite the frequent use of common biocides in circulating water streams, biofilm formation is a common problem in paper and board production

Method used

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  • Method for controlling growth of microorganisms and/or biofilms in an industrial process
  • Method for controlling growth of microorganisms and/or biofilms in an industrial process
  • Method for controlling growth of microorganisms and/or biofilms in an industrial process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Embodiment 1 (reference)

[0083] Tables 1 and 2 demonstrate the ability of the conventional antimicrobial agent DBNPA to prevent biofilm formation of Thermus rubrum (Meiothermus silvanus) and Pseudoxanthomonas taiwanensis. The test conditions simulate paper or board manufacturing process conditions (synthetic paper machine water, high temperature, presence of fibers, high fluidity). The conventional antimicrobial DBNPA requires an active compound dose of 1 mg / l to achieve acceptable or significant biofilm reduction efficacy. The results of DBNPA are given in Table 1 and Table 2.

[0084] Table 1 shows the effect of DPNPA dosage in SPW on Meiothermus silvanus biofilm at 45°C and 150 rpm (high mixing). Biofilms were stained and quantified by absorbance measurement. Doses are given as active ingredients.

[0085] Table 1

[0086]

[0087] Table 2 shows the effect of DPNPA dosage in SPW on Pseudoxanthomonas taiwanensis biofilm at 45°C and 150 rpm (high mixing). Bi...

Embodiment 2

[0090] Embodiment 2 (reference)

[0091] Tables 3 and 4 show the effect of the well-known antibiotic gramicidin on biofilm formation of Meiothermus silvanus and Pseudoxanthomonas taiwanensis. In the synthetic growth medium R2-broth, gramicidin was able to prevent biological film formation.

[0092] The results in Tables 3 and 4 demonstrate the expected behavior of clinical antimicrobial compounds with reduced performance when exposed to non-clinical conditions.

[0093] Table 3 shows the effect of gramicidin dosage on Meiothermus silvanus biofilm in R2-broth and SPW. Biofilms were stained and quantified by absorbance measurement. Doses are given as active ingredients.

[0094] table 3

[0095]

[0096] Table 4 shows the effect of gramicidin dosage on Pseudoxanthomonas taiwanensis biofilm in R2-broth and SPW. Biofilms were stained and quantified by absorbance measurement. Doses are given as active ingredients.

[0097] Table 4

[0098]

Embodiment 3

[0100] Tables 5 and 6 demonstrate the ability of Compound C and Compound E to prevent biofilm formation of Meiothermus silvanus and Pseudoxanthomonas taiwanensis. The test conditions are the same as those in Example 1. It was observed that Compound C and Compound E were able to control biofilms at very low concentrations. The biofilm reduction of active compound C or compound E at a dose of 0.2 mg / l was already more than 90%.

[0101] Table 5 shows the effect of Compound C dosage on Meiothermus silvanus biofilm in SPW at 45°C and 150 rpm (high mixing). Biofilms were stained and quantified by absorbance measurement. Compound C doses are given as active compound.

[0102] table 5

[0103]

[0104] Table 6 shows the effect of Compound E dosage on Meiothermus silvanus biofilm at 45°C and 150 rpm (high mixing). Biofilms were stained and quantified by absorbance measurement. Compound E doses are given as active compound.

[0105] Table 6

[0106]

[0107] The results i...

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Abstract

The invention relates to a method for controlling of a biofilm, for removing of a formed biofilm and / or for controlling a growth of microorganisms, preferably bacteria, in an aqueous environment of anindustrial manufacturing processcomprising cellulosic fibre material. A compound according to Formula I is administered to the aqueous environment of the process, in which Formula I R1, R2 and R3 independently represent a hydrogen atom; halogen atom; hydroxy group; amino group; alkylamino group, alkyl group, hydroxyalkyl group, haloalkyl group or alkoxy group having 1 to 4 carbon atoms; or an acylamido group having 1 to 10 carbon atoms; and A represents 2-thiazolamine; 2-propenenitrile; 2-propenoic acid; alkyl ester or hydroxyalkyl ester of 2-propenoic acid having 1 to 4 carbon atoms; or -CHCHCONR5R6 group, where R5 and R6 represent independently hydrogen atom, alkyl or hydroxyalkyl having 1 to 4 carbon atoms, with the proviso that the compound according to Formula I is not 3-[(4-methylphenyl)sulphonyl]-2-propenenitrile or 4-amino-N-2-thiazolyl-benzene-sulphonamide.

Description

technical field [0001] According to the preambles of the appended independent claims, the present invention relates to a method for controlling the growth of microorganisms and / or biofilms in industrial processes. Background technique [0002] Microorganisms are present in most industrial processes. Their presence is particularly troublesome in water-intensive processes, such as the manufacture of pulp, paper, cardboard, etc. Microorganisms thrive when process water contains biodegradable dissolved substances, and the temperature and pH of the process water are conducive to the survival of microorganisms. Microorganisms may enter the process through contamination of the air, incoming raw water, and / or non-sterile raw materials. Microorganisms can cause a wide range of problems in processes such as papermaking if measures are not taken against them. Problems associated with microorganisms include, for example, decomposition of chemical additives, deleterious changes in pro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D21C9/00D21H17/09D21H17/14D21H21/04D21H21/36
CPCD21C9/008D21H17/09D21H17/14D21H21/04D21H21/36
Inventor 亚科·西梅尔马科·科拉里乔纳·康恩
Owner KEMIRA OY
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