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Anticorrosive composition and application thereof

A composition and material technology, applied in the field of daily chemical industry, can solve the problems of narrow pH range, inability to apply skin care products, and affect the fragrance of formula, etc., and achieve the effect of strong irritation, excellent antiseptic and antibacterial effect

Inactive Publication Date: 2020-06-05
上海科颜生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The clinical investigation of the above-mentioned traditional preservatives shows that they are generally contact irritating and allergic: among them, methylisothiazolinone, DMDM ​​hydantoin and paraben can affect various molecular pathways in cells , which are restricted and banned by many countries and regions; sodium benzoate, potassium sorbate, etc. have a narrow pH range and cannot be applied to various skin care products; and the presence of phenoxyethanol will bring characteristic odor to the formula and affect the aroma of the formula

Method used

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  • Anticorrosive composition and application thereof
  • Anticorrosive composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Embodiment 1 provides a kind of antiseptic composition, comprises Zanthoxylum bungeanum extract, Xing'an Rubus seed extract, 1,2-hexanediol, p-hydroxyacetophenone; Said Zanthoxylum bungeanum extract, Xing'an Rubus seed extract The weight ratio of substances, alkane diols, and hydroxybenzophenones is 1:5.2:2.5:0.55.

[0077] The extracting method of described Zanthoxylum bungeanum extract comprises the steps:

[0078] Step 1: Weigh 25g of Zanthoxylum bungeanum, add 135mL of 95wt% ethanol, reflux and extract at 80°C for 3 times, each time for 1.5h, collect the filtrate and concentrate it under reduced pressure, add 25mL of water, extract and concentrate with dichloromethane to obtain Zanthoxylum bungeanum Treatment solution, and it is divided into Zanthoxylum bungeanum treatment solution A and Zanthoxylum bungeanum treatment solution B according to the weight ratio of 1:2.5;

[0079] Step 2: Use the Amberlite XAD-2 ion exchange resin adsorption column to separate the Zan...

Embodiment 2

[0088] Embodiment 2 provides a kind of antiseptic composition, comprises Zanthoxylum bungeanum extract, Xing'an Rubus seed extract, 1,2-hexanediol, p-hydroxyacetophenone; Said Zanthoxylum bungeanum extract, Xing'an Rubus seed extract The weight ratio of substances, alkane diols, and hydroxybenzophenones is 1:2.5:1.5:0.4.

[0089] The extracting method of described Zanthoxylum bungeanum extract comprises the steps:

[0090] Step 1: Weigh 20g of Zanthoxylum bungeanum, add 110mL of 95wt% ethanol to reflux and extract at 70°C for 3 times, each time for 1h, collect the filtrate and concentrate it under reduced pressure, add 20mL of water, extract and concentrate with dichloromethane to obtain Zanthoxylum bungeanum. liquid, and it is divided into Zanthoxylum bungeanum treatment solution A and Zanthoxylum bungeanum treatment solution B;

[0091] Step 2: Use the ion exchange resin adsorption column to separate the Zanthoxylum bungeanum treatment solution A, wash the impurity with dis...

Embodiment 3

[0100] Embodiment 3 provides a kind of antiseptic composition, comprises Zanthoxylum bungeanum extract, Xing'an Rubus seed extract, 1,2-hexanediol, p-hydroxyacetophenone; Said Zanthoxylum bungeanum extract, Xing'an Rubus seed extract The weight ratio of substances, alkane diols, and hydroxybenzophenones is 1:8.0:3.5:0.7.

[0101] The extracting method of described Zanthoxylum bungeanum extract comprises the steps:

[0102] Step 1: Weigh 30g of Zanthoxylum bungeanum, add 160mL of 95wt% ethanol, reflux and extract at 90°C for 3 times, each time for 2h, collect the filtrate and concentrate it under reduced pressure, add 30mL of water, extract and concentrate with dichloromethane to obtain Zanthoxylum bungeanum. liquid, and it is divided into Zanthoxylum bungeanum treatment solution A and Zanthoxylum bungeanum treatment solution B;

[0103] Step 2: Use the ion exchange resin adsorption column to separate the Zanthoxylum bungeanum treatment solution A, wash the impurity with disti...

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Abstract

The invention discloses an anticorrosive composition. The anticorrosive composition comprises a pericarpium zanthoxyli extract, a rubus chamaemorus seed extract, alkane diol and a hydroxybenzophenonesubstance. Skin care products fortified with the anticorrosive composition disclosed by the invention have excellent anticorrosive and bacteriostatic effects on bacteria such as bacillus pyocyaneus and staphylococcus aureus and fungi such as candida albicans and aspergillus niger; and meanwhile, known from effect evaluation tests, after two weeks of use, a consumer gains remarkable skin care effects of moisturizing, repairing, brightening and the like and is free of adverse phenomena such as skin allergy, high irritation, and flushing.

Description

technical field [0001] The invention belongs to the field of daily chemical industry, more specifically, the invention relates to an antiseptic composition and its application. Background technique [0002] Due to the high water content and rich nutrients in most of the formulas of skin care products, they are extremely susceptible to microbial contamination and lead to corruption during storage and use. In order to prevent skin care products from being polluted during the shelf life and use, a certain amount of ingredients with antibacterial and antiseptic functions need to be added. Due to the complex ingredients in skin care products, it will inevitably interfere with the effect of preservatives. Therefore, the selection or compounding of preservatives is a necessary link in the development of skin care products. [0003] In recent years, the existing preservatives in my country's skin care products market are often methylisothiazolinone, DMDM ​​hydantoin, phenoxyethanol...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/34A61K8/35A61Q19/00
CPCA61K8/345A61K8/35A61K8/9789A61K2800/524A61K2800/592A61Q19/00
Inventor 陈潇
Owner 上海科颜生物科技有限公司
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