Multi-taste elderberry effervescent tablet and preparation method thereof

A technology of elderberry and effervescent tablets, which is applied in pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., can solve problems such as poor taste, and achieve improved taste, excellent anti-oxidation, Improve shelf life

Pending Publication Date: 2020-12-01
新食代布丁(上海)智能科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The object of the present invention is to provide a kind of multi-taste elderberry effervescent tablet and pre

Method used

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  • Multi-taste elderberry effervescent tablet and preparation method thereof

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preparation example Construction

[0033] A preparation method of multi-taste elderberry effervescent tablet, the specific preparation steps comprising:

[0034] Preparation of compound elderberry powder:

[0035] In parts by weight, 10-20 parts of bananas, 10-20 parts of pineapples, 8-10 parts of strawberries, and 40-80 parts of elderberries are successively mixed and pulverized to obtain mixed fruit juice; then add mixed fruit juice with a quality of 1-3 % cellulase, and 1-3% pectinase of the mixed fruit juice mass, after constant temperature stirring and enzymolysis, enzyme inactivation, freeze-drying, to obtain compound elderberry powder;

[0036] Mixture:

[0037] In parts by weight, 3-5 parts of plant essential oil, 10-20 parts of compound elderberry powder, 8-10 parts of binder, 10-20 parts of disintegrating agent, 3-5 parts of sweetener, 3-5 parts of fructose, 8-10 parts of amino acids, 3-5 parts of sodium bicarbonate; first mix the compound elderberry powder, disintegrant, binder, sweetener, fructose...

Embodiment 1

[0044] Preparation of compound elderberry powder:

[0045] According to parts by weight, take 10 parts of bananas, 10 parts of pineapples, 8 parts of strawberries, and 40 parts of elderberries, mix them into a juice extractor, grind them into fruit juices, and obtain mixed fruit juices; then add mixed fruit juices to the mixed fruit juices 1% cellulase by mass, and 1% pectinase by mass of mixed fruit juice, at a temperature of 30°C and a rotational speed of 300r / min, stir and enzymolyze at a constant temperature for 3 hours, inactivate the enzyme, freeze-dry, and discharge , to compound elderberry powder;

[0046] Mixture:

[0047] In parts by weight, successively take 3 parts of plant essential oil, 10 parts of compound elderberry powder, 8 parts of binder, 10 parts of disintegrant, 3 parts of sweetener, 3 parts of fructose, 8 parts of amino acid, 3 parts of Sodium bicarbonate; after stirring and mixing the compound elderberry powder, disintegrant, binder, sweetener, fructo...

Embodiment 2

[0054] Preparation of compound elderberry powder:

[0055] According to parts by weight, take 20 parts of bananas, 20 parts of pineapples, 10 parts of strawberries, and 80 parts of elderberries, mix them into a juice extractor, grind them into fruit juices, and obtain mixed fruit juices; then add mixed fruit juices to the mixed fruit juices 3% cellulase by mass, and 3% pectinase by mass of mixed fruit juice, at a temperature of 35°C and a rotational speed of 500r / min, stir and enzymolyze at a constant temperature for 5 hours, inactivate the enzyme, freeze-dry, and discharge , to compound elderberry powder;

[0056] Mixture:

[0057] In parts by weight, take 5 parts of plant essential oils successively, 20 parts of compound elderberry powder, 10 parts of binders, 20 parts of disintegrants, 5 parts of sweeteners, 5 parts of fructose, 10 parts of amino acids, 5 parts of Sodium bicarbonate; after stirring and mixing the compound elderberry powder, disintegrant, binder, sweetener...

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Abstract

The invention discloses a multi-taste elderberry effervescent tablet and a preparation method thereof. The effervescent tablet is prepared from 3-5 parts of plant essential oil, 10-20 parts of compound elderberry powder, 8-10 parts of an adhesive, 10-20 parts of a disintegrating agent, 3-5 parts of a sweetening agent, 3-5 parts of fructose, 8-10 parts of amino acid and 3-5 parts of sodium bicarbonate. The fructose and the amino acid are at least partially combined in a chemical bond form to form a Schiff base and/or Amazuril product. The preparation method comprises the following steps: mixingbananas, pineapples, strawberries and elderberry, and performing crushing to obtain mixed juice; adding cellulase and pectinase, carrying out constant-temperature stirring enzymolysis, deactivating enzymes, and carrying out freeze drying so as to obtain a compound elderberry powder; stirring and mixing the compound elderberry powder, the disintegrating agent, the adhesive, the sweetening agent, the fructose, the amino acid and the sodium bicarbonate, then adding the plant essential oil, and continuously performing stirring and mixing uniform to obtain a mixture; and pressing the mixture intotablets in an inert gas protection state at a temperature of 50-65 DEG C, and performing discharging to obtain the effervescent tablet.

Description

technical field [0001] The invention relates to the technical field of effervescent tablets, in particular to a multi-taste elderberry effervescent tablet and a preparation method thereof. Background technique [0002] The prescription of effervescent tablet is composed of main drug, diluent, binder, disintegrant, lubricant and other excipients. It is necessary to select the appropriate variety according to the preparation process. Different from ordinary tablets, the disintegrants used in effervescent tablets are effervescent disintegrants. Effervescent disintegrators include acid sources and alkali sources. Commonly used acid sources include citric acid, malic acid, boric acid, tartaric acid, Malic acid, inorganic mineral acid (hydrochloric acid), etc.; commonly used alkali sources are sodium bicarbonate, sodium carbonate and a mixture of the two. The acid-base ratio has a significant impact on the preparation and stability of effervescent tablets. It is generally believ...

Claims

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Application Information

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IPC IPC(8): A61K9/46A61K47/02A61K47/26A61K47/18A61K47/44A61K47/10A61K47/28A61K47/36A61K36/88
CPCA61K9/0007A61K9/2095A61K9/2009A61K9/2018A61K9/2013A61K9/2068A61K9/2031A61K9/2059A61K36/88A61K36/73A61K36/35A61K2300/00
Inventor 何楠覃扬
Owner 新食代布丁(上海)智能科技有限公司
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