Oral care composition containing bioactive material and spherical silicon dioxide

A technology of spherical silica and oral care, which is applied in the direction of oral care, medical preparations containing active ingredients, cosmetic preparations, etc., which can solve the problems of inability to meet daily consumption needs, low deposition and remineralization rates, and remineralization Single mechanism and other problems, to achieve the effect of promoting tooth remineralization, sterilization and anti-inflammation, relatively low cost, and wide applicability

Pending Publication Date: 2021-04-09
广州舒客实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] There are following deficiencies in the above-mentioned prior art: (1) Calcium, phosphorus ion deposition and remineralization rate are low, and remineralization effect is different
(2) The protein structure is complex, and some people are allergic to protein
(3) The remineralization mechanism is sin

Method used

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  • Oral care composition containing bioactive material and spherical silicon dioxide
  • Oral care composition containing bioactive material and spherical silicon dioxide
  • Oral care composition containing bioactive material and spherical silicon dioxide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] An oral care composition comprising bioactive glass and spherical silica, comprising the following components by weight percentage:

[0052]

[0053]

[0054] Disperse carbomer and PVP homogeneously in polyethylene glycol-8, add glycerin and stir to form a gel, then add spherical silica, silicon dioxide, bioactive glass, sodium fluoride, sodium saccharin and titanium dioxide, stir, and finally add Sodium lauryl sulfate, cocamidopropyl betaine and flavor, stirred and degassed to make a toothpaste containing the composition.

Embodiment 2

[0056] An oral care composition comprising bioactive glass and spherical silica, comprising the following components by weight percentage:

[0057]

[0058] Disperse carbomer and PVP homogeneously in polyethylene glycol-8, add glycerin and stir to form a gel, then add spherical silica, silicon dioxide, bioactive glass, sodium fluoride, sodium saccharin and titanium dioxide, stir, and finally add Sodium lauryl sulfate, cocamidopropyl betaine and flavor, stirred and degassed to make a toothpaste containing the composition.

Embodiment 3

[0060] An oral care composition comprising bioactive glass and spherical silica, comprising the following components by weight percentage:

[0061]

[0062] Disperse carbomer and PVP homogeneously in polyethylene glycol-8, add glycerin and stir to form a gel, then add spherical silica, silicon dioxide, bioactive glass, sodium fluoride, sodium saccharin and titanium dioxide, stir, and finally add Sodium lauryl sulfate, cocamidopropyl betaine and flavor, stirred and degassed to make a toothpaste containing the composition.

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Abstract

The invention relates to an oral care composition containing a bioactive material and spherical silicon dioxide. The oral care composition comprises the bioactive material, fluoride and the spherical silicon dioxide, wherein the D50 median particle size of the spherical silicon dioxide is 3.5-4 microns, the D95 particle size is smaller than 8 microns, the oil absorption value is smaller than 100cc/100g, and the sphericity coefficient is not smaller than 0.9. The particle size of the spherical silicon dioxide particles is equivalent to the pipe diameter of a dental tubule, and the particles are relatively complete spheres, so that the composition can be used for blocking the dental tubule when used as an oral care product, and the sensitivity of teeth is reduced. In addition, the spherical silicon dioxide can also be used as an abrasive and has relatively high cleaning power, and the particles are spherical, so that the wear to enamel can be reduced. Due to compounding of the three substances, remineralization and acid erosion resistance of the enamel dentin can be effectively promoted, and the problems of decayed teeth and tooth sensitivity are improved.

Description

technical field [0001] The invention belongs to the technical field of oral care compositions, in particular to an oral care composition comprising bioactive materials and spherical silicon dioxide. Background technique [0002] In recent years, with the changes in people's dietary structure and the increase in the consumption of acidic beverages, the prevalence of acid erosion and even dental caries continues to increase. Dental hard tissues in the oral environment are constantly undergoing demineralization and remineralization. The health of teeth depends on this balance. When demineralization is greater than remineralization and lasts for a period of time, caries will occur. Enamel is the outermost layer of tooth tissue and is where caries first occurs. The formation of enamel caries is mainly the result of the disruption of the dynamic balance of enamel demineralization and remineralization. Remineralization is the process of depositing calcium, phosphorus, and other m...

Claims

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Application Information

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IPC IPC(8): A61K8/25A61K8/19A61K8/24A61K8/21A61Q11/00
CPCA61K8/25A61K8/19A61K8/24A61K8/21A61Q11/00A61K2800/592A61K2800/5922
Inventor 陈敏珊谢晓芳郑晓霞肖俊芳
Owner 广州舒客实业有限公司
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