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An intelligent temperature-sensitive hair dye that reduces the entry of aniline substances into the human body and its preparation method

A temperature-sensitive, hair dye technology, applied in the field of designing cosmetics, can solve the problems of scarcity of colors, long dyeing time, difficult extraction, etc., and achieve the effects of rich color selection, good color fastness, and short dyeing time

Active Publication Date: 2022-03-04
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the shortcomings of oxidative hair dyes, many experts turn to research on plant pigment hair dyes. Natural pigment sources minimize the harm of hair dyes to the human body, but the color fastness of plant pigments is low, the color types are scarce, extraction is difficult, and the dyeing time Longer and other disadvantages make it far behind oxidative hair dyes in terms of hair dyeing performance
The only disadvantage of oxidative hair dyes is that they are harmful to the human body.

Method used

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  • An intelligent temperature-sensitive hair dye that reduces the entry of aniline substances into the human body and its preparation method
  • An intelligent temperature-sensitive hair dye that reduces the entry of aniline substances into the human body and its preparation method
  • An intelligent temperature-sensitive hair dye that reduces the entry of aniline substances into the human body and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Example 1: Study on the sustained release properties of Poosham hydrogel on phenylenediamine transdermal

[0049] The traditional hair dye formula [A agent (mass percent): deionized water 93.2%, 2% phenylenediamine, 1% emulsified silicon oil, 0.5% sodium sodium sulfate, EDTA; ammonia water; B dose: from 93.5%, hydrogen peroxide 6%, Carropham 0.5%], poloxham, and polithamimosham adding alginate to 2H transdermal experiments, and control the concentration of phenylenediamine 20 mg / ml, taking 2 mL under transdermal experiment at 32 ° C, the effect of removing oxidant, the experimental results figure 1 :

[0050] As can be seen from the experimental results of the above figure, the traditional hair dye has the largest transdermal amount of 1110 μg / cm2, and the amount of poloham hydrogel transdermal is decreased without adding the oalcate. It is 758μg / cm2, adding seaweed. The amount of water gel of sodium sodium is further reduced, and less than half of the transdermal amo...

Embodiment 2

[0051] Example 2: Preparation of cationic bonchri surfactants containing an amide group and an ester functional group

[0052] (1) Preparation of 1,2-bis (bromoacetoxy) ethane

[0053] The reaction was distilled with bromoacetic acid (0.21 mol) and ethylene glycol (0.1 mol) at 130 ° C without solvent conditions for 6 h. After the reaction is completed, the reactive crude mixture was first washed twice with 200 ml of deionized water, and then washed once with a mixed solution of 100 ml of methanol water (where 80 ml of methanol, 20 mL) was washed once, and the washed product was dissolved in trichloromethane. Then dry with anhydrous sodium sulfate, and finally evaporated to remove dichloromethane to give an oily liquid. The yield of the reaction was 47% by the total mass quality of the above-mentioned product was 47%, and by IR and 1 H NMR characterizes the purified target compound.

[0054]

[0055] (2) Preparation of N- [3- (dimethylamino) propyl] fatamide

[0056] First, fatty...

Embodiment 3

[0087] Example 3: The specific components of the prepared A agents and B agents are as follows:

[0088] A agent:

[0089]

[0090]

[0091] B dose:

[0092]

[0093] The above A and B binders are mixed together, stir well, apply it on a clean hair, attenuately maintained 30 minutes, and then clean the hair and clean it.

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Abstract

The invention provides an intelligent temperature-sensitive hair dye that reduces the entry of aniline substances into the human body and a preparation method thereof, belonging to the technical field of cosmetics. The invention adopts poloxamer solution with temperature-sensitive performance as a solvent to load aniline dye molecules, so that the hair dye can form a gel after contacting human skin, slow down the release speed of aniline dyes, thereby reducing the amount of aniline dyes Harm to the human body. And because it is not a gel on the hair, it has little effect on the coloring effect on the hair. Especially for oxidative hair dyes, different aniline dyes can be added to prepare different colors.

Description

Technical field [0001] The present invention is designed in the field of cosmetic technology, and more particularly to a temperature sensitive intelligent hair dye composition and a preparation method thereof. Background technique [0002] With the development of the times, people are increasingly focusing on fashion pursuit. The arrival of aging society, many elderly people have been in a young state through dye, and the hair dye is a kind of cosmetics that can change the original color of the hair, and have a different generation of consumers, and dye the hair in different colors. Zhang Yang's personality. However, the mainstream oxide hair dye on the market contains an aniline dye, which has certain toxicity and irritation, which may cause serious adverse reactions that may cause skin cancer, liver cancer, thyroid cancer and lymphatic. Tumor and other diseases. For the hairdresses industry practitioners and hairdresses, this is undoubtedly serious harm to their health. [0003...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/86A61K8/41A61K8/25A61K8/67A61K8/24A61K8/44A61K8/49A61K8/73A61K8/42A61K8/34A61K8/23A61Q5/10C07C231/12C07C233/36
CPCA61K8/86A61K8/411A61K8/25A61K8/676A61K8/24A61K8/44A61K8/4913A61K8/41A61K8/733A61K8/42A61K8/342A61K8/23A61Q5/10C07C231/12C07C233/36
Inventor 高海燕雷月王建国周越许虎君
Owner JIANGNAN UNIV
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