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Root canal filling agent

A filling agent and root canal technology, applied in dental preparations, dentistry, anti-inflammatory agents, etc., can solve the problems of poor antibacterial properties, irritating periapical tissue, and less research, so as to improve antibacterial properties and relieve pain. The effect of pain and improvement of curative effect

Inactive Publication Date: 2021-10-26
QINGDAO STOMATOLOGICAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the antibacterial components of traditional root canal fillings mainly include formaldehyde cresol, camphorol and paraformaldehyde. Although formaldehyde cresol and camphorol have strong cytotoxicity, they are also irritating to the periapical tissue. , and may become a sensitizer to sensitize the body; although paraformaldehyde has the effect of drying, hardening and fixing the residual dental pulp tissue at the root tip, and disinfecting the root canal, paraformaldehyde can release formaldehyde, which is harmful to human health. Negative Effects
[0004] Compared with chemical drugs, traditional Chinese medicines have mild efficacy and poor antibacterial properties, and there are many kinds of traditional Chinese medicines and complex drug compatibility, so there are few studies on the use of traditional Chinese medicines for root canal fillings.

Method used

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preparation example Construction

[0022] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition, comprising: mixing the crushed honeysuckle, dandelion, red peony root, angelica dahurica, chrysanthemum and licorice with an ethanol solution with a volume fraction of 45-70%. Reflux extraction at ℃ for 2-4 hours, concentrate and vacuum freeze-dry to obtain powder 1; stir-fry the frankincense at 130-150°C for 3-8 minutes, add acetic acid with a volume fraction of 6%-10%, and stir-fry until the surface Brighten and pulverize to obtain powder 2; mix powder 1 and powder 2 to obtain the traditional Chinese medicine composition for tooth root filling.

[0023] In the present invention, the crushed honeysuckle, dandelion, red peony, angelica, chrysanthemum and licorice are preferably passed through a 120-200 mesh sieve, more preferably a 150 mesh sieve. In the present invention, the mass volume ratio of the honeysuckle, dandelion, red peony, angelica, chry...

Embodiment 1

[0032] Weigh 28g of honeysuckle, 28g of dandelion, 17g of red peony, 17g of frankincense, 12g of Angelica dahurica, 12g of chrysanthemum, and 8g of licorice. After crushing honeysuckle, dandelion, red peony root, angelica, chrysanthemum and licorice through a 150-mesh sieve, mix them with ethanol solution with a volume fraction of 55%, reflux extraction at 48°C for 3 hours, concentrate to a relative density of 1.7, and store at -15°C Freeze-dry under vacuum for 17 hours to obtain powder 1; fry frankincense at 140°C for 5 minutes, add 1 mL of acetic acid with a volume fraction of 8%, stir-fry until the surface is bright, and pulverize through a 250-mesh sieve to obtain powder 2; Mix the solid 1 and the powder 2 to obtain a traditional Chinese medicine composition.

[0033] Take by weighing calcium hydroxide 28g, iodoform 13g, Chinese medicine composition 4g, glycerin 6g, barium sulfate 5g, distilled water 40g, iodoform, glycerol and distilled water are mixed, obtain mixed solut...

Embodiment 2

[0035] Weigh 25g of honeysuckle, 25g of dandelion, 20g of red peony, 20g of frankincense, 10g of angelica, 10g of chrysanthemum, and 10g of licorice. After crushing honeysuckle, dandelion, red peony, angelica, chrysanthemum and licorice through a 120-mesh sieve, mix with ethanol solution with a volume fraction of 70%, reflux extraction at 43°C for 4h, concentrate to a relative density of 1.5, and store at -20°C Freeze-dry under vacuum for 15 hours to obtain powder 1; fry frankincense at 145°C for 4 minutes, add 0.5 mL of acetic acid with a volume fraction of 9%, stir-fry until the surface is bright, and pulverize through a 200-mesh sieve to obtain powder 2; Powder 1 and powder 2 are mixed to obtain a traditional Chinese medicine composition.

[0036]Take by weighing calcium hydroxide 25g, iodoform 15g, Chinese medicine composition 3g, glycerin 8g, barium sulfate 4g, distilled water 35g, iodoform, glycerin and distilled water are mixed, obtain mixed solution, calcium hydroxide,...

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Abstract

The invention provides a root canal filling agent, and belongs to the technical field of medical materials. The root canal filling agent comprises a traditional Chinese medicine composition, the traditional Chinese medicine composition comprises honeysuckle, dandelions, red paeony roots, frankincense, angelica dahurica, chrysanthemums and liquorice, the honeysuckle and the dandelions are used for sterilizing, diminishing inflammation and clearing away heat and toxic materials and serve as monarch drugs, the red paeony roots and the frankincense are used for promoting blood circulation to remove blood stasis and relieving swelling and pain and serve as ministerial drugs, the angelica dahurica and the chrysanthemums are used for promoting blood circulation to expel pus and serve as adjuvant drugs, the liquorice is used for neutralizing, relieving urgency and coordinating the drug actions and serves as conductant drugs, and all the drugs are compatible to achieve the effects of diminishing inflammation, clearing heat and relieving swelling and pain. Experimental results show that when a traditional Chinese medicine composition is applied to the root canal filling agent, not only is the antibacterial property of the root canal filling agent improved, but also the curative effect of the root canal filling agent is remarkably improved, and the pain of a patient is relieved.

Description

technical field [0001] The invention belongs to the technical field of medical materials, in particular to a root canal filling agent. Background technique [0002] Root canal therapy is the most commonly used effective treatment for pulp disease and periapical disease in the world. The principle of root canal treatment is to remove most of the infected substances in the root canal through mechanical and chemical methods, and to prevent the occurrence of periapical lesions or promote the healing of periapical lesions that have occurred by filling the root canal and sealing the crown. The main steps of root canal treatment include root canal preparation, root canal disinfection and root canal filling. Due to the complexity of the root canal system, conventional mechanical preparation can only remove most of the infected tissue, but cannot completely remove it, and the remaining bacteria and toxins in the deep dentin tubules and side branch root canals rely solely on manual i...

Claims

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Application Information

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IPC IPC(8): A61K6/54A61K6/56A61K6/71A61K36/65A61K36/71A61P31/04A61P29/00
CPCA61K6/56A61K6/54A61K6/71A61K36/355A61K36/288A61K36/71A61K36/65A61K36/324A61K36/232A61K36/287A61K36/484A61P31/04A61P29/00A61K2300/00
Inventor 李杰
Owner QINGDAO STOMATOLOGICAL HOSPITAL