Healthy food composition rich in plant polyphenols and sterol

A composition and food technology, applied in the direction of drug combinations, medical preparations containing active ingredients, plant raw materials, etc., can solve the lack of research on synergistic effects, lack of multi-level, multi-target, multi-angle system research on plant active ingredients, Lack of overall research on compound components, etc., to achieve the effects of large side effects, improvement of hyperglycemia, and reduction of lipid accumulation

Pending Publication Date: 2021-11-02
北京曜食同源商贸有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Despite the above reports, there is still a lack of multi-level, multi-target, multi-angle systematic research on plant active ingredients, and a lack of holistic research on compound components. For the relationship between different types of components, such as the relationship between grains and Chinese medicinal materials The synergistic effect is lack of corresponding research

Method used

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  • Healthy food composition rich in plant polyphenols and sterol
  • Healthy food composition rich in plant polyphenols and sterol
  • Healthy food composition rich in plant polyphenols and sterol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 composition of the present invention lowers blood sugar to the animal experiment of mouse

[0030] 1 Animals and Feed

[0031] Adult male C57BL / 6J mice of SPF grade, body weight 22±2g, license number SCXK (Beijing) 2008-0002. Raised in a barrier environment animal laboratory, certificate number SCXK (Beijing) 2011-0024, room temperature 20°C, relative humidity about 45%, light-dark cycle (12h / 12h). Ordinary feed and high-fat feed (20% sucrose, 2.5% cholesterol, 10% lard, 1% sodium cholate, 66.5% basic feed)

[0032] 2 Instruments and reagents

[0033] Fully automatic biochemical analyzer (Shenzhen Mindray Biomedical Electronics Co., Ltd.), Bai'ankang rapid blood glucose meter, disposable blood glucose test strips, iMark microplate reader (Bio-rad, USA), high-speed centrifuge (5424, Eppendorf, Germany); Electronic analytical balance (AX120, Shimadzu, Japan), etc.

[0034] Streptozotocin (Sigma, USA), insulin kit (Tianjin Shengda Biotechnology Co., Ltd.)....

Embodiment 2

[0052] Embodiment 2 The clinical research of composition of the present invention on human body hypoglycemic

[0053] 1. Research objects: 10 patients with type 2 diabetes were recruited in this study, and they were divided into compound cereal group (the specific composition and dosage ratio were the same as in Example 1, and the mixed powder was taken directly) and buckwheat group. Inclusion criteria: in line with the Chinese T2DM prevention and treatment The diagnostic criteria for T2DM in the guidelines (2017 edition) are fasting blood glucose ≥ 7.0mmol / L and glycated hemoglobin ≥ 6.3%. Exclusion criteria: ① patients with gestational diabetes or type 1 diabetes; ② patients with serious primary diseases of heart, liver, kidney, lung, brain and other organs; ③ patients with acute complications such as diabetic ketosis and infection.

[0054] 2. Experimental grouping: After signing the informed consent form, type 2 diabetic patients, on the basis of conventional treatment, re...

Embodiment 3

[0066] The preparation method of embodiment three compositions of the present invention

[0067] Quinoa, highland barley, buckwheat, and oats are washed and dried, according to 45 parts by weight of quinoa, 20 parts by weight of oats, 10 parts by weight of highland barley, 10 parts by weight of buckwheat, 5 parts by weight of buckwheat bran, and 5 parts by weight of buckwheat germ. 3 parts by weight of Rhizoma Polygonatum and 2 parts by weight of Radix Puerariae are put into a pulverizer, and pulverized for 30-40 seconds at 30000-39000 rpm to obtain mixed powder. Mix it with deionized water and make strips about 6 cm long and 1.5 cm in diameter.

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Abstract

The invention relates to a healthy food composition which is composed of cereals rich in plant polyphenol and sterol, traditional Chinese medicines and yeast, the cereals are one or more of quinoa, oat, buckwheat, highland barley, buckwheat bran and buckwheat germs, and the traditional Chinese medicines are one or two of rhizoma polygonati and radix puerariae. The synergistic hypoglycemic effect is achieved through the comprehensive action of various bioactive substance groups, multi-level, multi-target and multi-angle synergistic interaction of polyphenol, sterol, dietary fiber, protein, polypeptide, oligopeptide, [beta]-glucan, flavone, D-chiro-inositol, ecdysone and the like is achieved, and an excellent effect is shown in mouse hypoglycemic experiments and clinical experiments.

Description

technical field [0001] The invention belongs to the field of health food, in particular to a health food composition rich in plant polyphenols and sterols. Background technique [0002] According to the statistics of the International Diabetes Association, the number of people with diabetes in the world has exceeded 415 million in 2015, and it is predicted that the number of people with diabetes will reach 642 million by 2040. Therefore, the prevention and treatment of diabetes is imminent. Western medicine treatment has large side effects and poor curative effect. Traditional Chinese medicine has its unique advantages in treating diabetes. Applying the theory of "prevention of disease" and "medicine and food from the same source" to the prevention and treatment of diabetes is an important way to delay the occurrence and development of diabetes. In the clinical prevention and treatment of diabetes, the key is diet therapy, which runs through the disease. Traditional Chines...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00A23L7/10A23L33/10A23L33/14A23L7/152A61K36/899A61P3/10
CPCA23L33/00A23L7/10A23L33/10A23L33/14A23L7/152A23L7/115A61K36/21A61K36/899A61K36/70A61K36/8969A61K36/488A61P3/10A23V2002/00A61K2300/00A23V2200/328
Inventor 刘庆
Owner 北京曜食同源商贸有限公司
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