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Preparation method of lycium barbarum polysaccharide-lycium barbarum seed oil soft capsule

A technology of Lycium barbarum polysaccharides and Lycium barbarum seed oil, which is applied in capsule delivery, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve problems such as inability to combine Lycium barbarum seed oil, polysaccharide flocculation and precipitation, and general product quality, and achieve significant in vitro Antioxidant activity, high biological activity, easy cleaning and recovery effect

Active Publication Date: 2021-12-07
宁夏沃福百瑞枸杞产业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It also contains a large amount of phospholipids, which can lower plasma cholesterol, reduce blood vessel wall cholesterol deposition, and prevent blood lipid atherosclerosis. Lycium barbarum polysaccharides and wolfberry seed oil can be prepared into capsules; in the preparation of traditional wolfberry polysaccharide-seed oil capsules, the prepared The product quality is average, the production cost is high, and there are certain irrationality in the process
[0003] Because Lycium barbarum polysaccharide molecules are hydrophilic and oleophobic, they cannot be well combined with Lycium barbarum seed oil. The Lycium barbarum polysaccharide-Lycium barbarum seed oil products with existing technical indicators will have polysaccharide flocculation after being placed for a period of time Precipitation phenomenon, affecting product quality

Method used

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  • Preparation method of lycium barbarum polysaccharide-lycium barbarum seed oil soft capsule
  • Preparation method of lycium barbarum polysaccharide-lycium barbarum seed oil soft capsule
  • Preparation method of lycium barbarum polysaccharide-lycium barbarum seed oil soft capsule

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Effect test

Embodiment 1

[0063] The preparation method of the wolfberry polysaccharide-lycium barbarum seed oil soft capsule comprises the following steps: S1 extraction of the wolfberry polysaccharide; S2 molecular modification of the wolfberry polysaccharide; S3 extraction of the wolfberry seed oil; S4 preparation of the wolfberry polysaccharide-lycium seed oil soft capsule.

[0064] S1 Lycium barbarum polysaccharide extraction, including:

[0065] S11. Screen dried or fresh wolfberry fruit, remove impurities and diseased fruits, wash, dry, pulverize, sieve, and pass through a 40-mesh sieve to obtain wolfberry powder;

[0066] S12, take 10000g of wolfberry powder obtained in step S11, add pure water according to the ratio of material to liquid 1:6, carry out microwave treatment at room temperature first, microwave power 250w, processing time 10min; then carry out ultrasonic treatment, ultrasonic power 150w, ultrasonic frequency 25Hz , processing time 11min, filter, and collect the filtrate;

[0067...

Embodiment 2

[0085] The preparation method of wolfberry polysaccharide-lycium seed oil soft capsule comprises the following steps: S1 extraction of wolfberry polysaccharide; S2 molecular modification of wolfberry polysaccharide; S3 extraction of wolfberry seed oil; S4 preparation of wolfberry polysaccharide-lycium seed oil soft capsule

[0086] S1 Lycium barbarum polysaccharide extraction, including:

[0087] S11. Screen dried or fresh wolfberry fruit, remove impurities and diseased fruits, wash, dry, pulverize, sieve, and pass through a 40-mesh sieve to obtain wolfberry powder;

[0088] S12, take 10000g of wolfberry powder obtained in step S11, add pure water according to the ratio of material to liquid 1:5, carry out microwave treatment at room temperature first, microwave power 400w, processing time 14min; then carry out ultrasonic treatment, ultrasonic power 250w, ultrasonic frequency 25Hz , processing time 15min, filter, and collect the filtrate;

[0089] S13. Pass the filtrate obtai...

Embodiment 3

[0107] The preparation method of wolfberry polysaccharide-lycium seed oil soft capsule comprises the following steps: S1 extraction of wolfberry polysaccharide; S2 molecular modification of wolfberry polysaccharide; S3 extraction of wolfberry seed oil; S4 preparation of wolfberry polysaccharide-lycium seed oil soft capsule

[0108] S1 Lycium barbarum polysaccharide extraction, including:

[0109] S11. Screen dried or fresh wolfberry fruit, remove impurities and diseased fruits, wash, dry, pulverize, sieve, and pass through a 40-mesh sieve to obtain wolfberry powder;

[0110] S12, get 10000g of wolfberry powder obtained in step S11, add pure water according to the ratio of material to liquid ratio of 1:7, carry out microwave treatment at room temperature first, microwave treatment is microwave power 300w, treatment time 12min; then carry out ultrasonic treatment, ultrasonic power 200w, Ultrasonic frequency 25Hz, treatment time 14min, filter, collect filtrate;

[0111] S13. Pas...

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Abstract

The invention provides a preparation method and application of lycium barbarum polysaccharide, and belongs to the technical field of food processing. The preparation method comprises the following specific steps: extracting lycium barbarum polysaccharide, modifying lycium barbarum polysaccharide molecules, extracting lycium barbarum seed oil and preparing the lycium barbarum polysaccharide-lycium barbarum seed oil soft capsule. The preparation method has the beneficial effects that sorbitan monooleate is added to completely fuse the lycium barbarum polysaccharide and the lycium barbarum seed oil, so that an emulsified liquid can be prevented from settling, layering and flocculation phenomena of the lycium barbarum polysaccharide and the lycium barbarum seed oil can be prevented, and the amount of hydroxyl substituted by acetyl in the lycium barbarum polysaccharide is about 8-10% due to the added acetyl group and a proper amount of acetyl is added into the lycium barbarum polysaccharide, so that the emulsibility of the lycium barbarum polysaccharide is improved; certain carboxymethyl is added to lycium barbarum polysaccharide, so that hydroxyl is substituted by carboxymethyl, the substitution degree is about 5%-10%, and the capabilities of the lycium barbarum polysaccharide-lycium barbarum seed oil in the characteristics of immunoregulation, oxidation resistance and the like are improved.

Description

technical field [0001] The invention relates to the technical field of food processing, in particular to a preparation method of wolfberry polysaccharide-lycium barbarum seed oil soft capsules. Background technique [0002] Lycium barbarum is the dry and mature fruit of Ningxia Lycium barbarum, a perennial shrub of the family Solanaceae. Goji berries are widely used as dietary supplements in addition to their medicinal uses. Lycium barbarum contains phenylpropyl esters, flavonoids, polyphenols and polysaccharides, among which more than 50% are Lycium barbarum polysaccharides. It has biological functions such as regulating immunity, anti-oxidation and anti-aging, protecting the liver, lowering blood pressure, lowering blood sugar, regulating blood lipids, and enhancing cell activity. Lycium barbarum seed oil is called "vascular scavenger", and its unsaturated fatty acid, linolenic acid, and oleic acid content are as high as 85%. It also contains a large amount of phospholi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K36/815A61P3/10A61P37/04A61P39/06C08B37/00A61K31/715A61K131/00
CPCA61K36/815A61K31/715A61K9/4825A61K9/4858A61P3/10A61P39/06A61P37/04C08B37/0003C08B37/00A61K2236/331A61K2236/53A61K2236/51A61K2300/00Y02A50/30
Inventor 郭荣潘泰安邱华龚媛潘嘉钰
Owner 宁夏沃福百瑞枸杞产业股份有限公司
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