Nano spectrum endermatic medicinal paste and its preparation

A kind of nano-Chinese medicine and nano-technology, which is applied in the direction of drug devices, aerosol delivery, and other medical devices, can solve the problems of unable to achieve the purpose of slow release or controlled release, not paying attention to long-term curative effect, and non-durable drug effect, etc., to achieve The effect of preventing local hyperemia, avoiding the loss of active ingredients, and preventing the leakage of liquid in the blood

Inactive Publication Date: 2004-12-08
史长明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is a development process for transdermal external plasters. It has gone through four development periods from the traditional black plaster to the present: the first generation of patches: traditional patches, commonly known as dog skin plasters, which have the advantage of adopting the traditional Theoretically, it pioneered the internal and external treatment of bone diseases, and it is easy to carry; its disadvantages are 1. It is inconvenient to use, smells bad, airtight, and has a strong feeling of foreign body application; 2. Affected by the seasons, it is not easy to melt in cold weather. Open, it is hot and easy to melt, the drug loss is serious, and it is easy to contaminate the clothes, and it cannot be washed off; the second generation patch: chemical patch, such as common pain relief cream, joint cream, etc., its advantage is easy to carry , easy to use, low price; its disadvantages are 1. Zinc oxide adhesive plaster is used as the carrier, the skin cannot breathe, and allergic symptoms such as skin redness, ulceration, and spots are prone to occur; 2. Chemical glue is added in the production proces

Method used

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  • Nano spectrum endermatic medicinal paste and its preparation
  • Nano spectrum endermatic medicinal paste and its preparation

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Embodiment

[0051] Embodiment: a kind of nano-spectrum drug patch for transdermal administration (see figure 1 ), which is characterized in that it is composed of a base material lining layer 1, a medicine storehouse layer 2, a matrix gel layer 3 and an isolation protective layer 4, and the said medicine storehouse layer 2 is a nanometer Chinese medicine powder layer 2a, a composite nanometer The infrared powder layer 2b, the transdermal absorption enhancer layer 2c, and the slow-release agent layer 2d are composed.

[0052] The base material liner 1 mentioned above is a spunlace nonwoven fabric layer.

[0053] In the above-mentioned nano Chinese medicine powder layer 2a, the diameter of the nano Chinese medicine powder is 200nm, and the plant cell wall and cell membrane of the Chinese herbal medicine are broken, so that the active ingredients of the plant and the compatibility of the plant powder are retained.

[0054] The above-mentioned composite nano far-infrared powder layer 2b can ...

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Abstract

A medicinal picking for percutaneous absorption of medicine is composed of a substrate layer, the medicine-bearing layer consisting of nano-class Chinese medicine layer, nano-class far infrared layer, percutaneous absorption promoting layer and slow-releasing agent layer, an adhesive layer, and a protecting layer. Its preparing process is also disclosed. Its advantages are high medical effect and air permeability, and no irritation to skin.

Description

(1) Technical field: [0001] The invention relates to a drug patch for transdermal administration and a manufacturing method thereof, in particular to a nano-spectrum drug patch for transdermal drug administration and a manufacturing method thereof. (two) background technology: [0002] Transdermal delivery systems (TDS) refer to controlled-release preparations that are administered through the skin to achieve systemic therapeutic effects. TDS is a very promising dosage form, and its research has become one of the central contents of the development and research of the third generation of pharmaceutical preparations. There is a development process for transdermal external plasters. It has gone through four development periods from the traditional black plaster to the present: the first generation of patches: traditional patches, commonly known as dog skin plasters, which have the advantage of adopting the traditional Theoretically, it pioneered the internal and external trea...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61M37/00
Inventor 史长明
Owner 史长明
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