In-vivo real-time photo-sensitive blood pH value sensor and its making method

Abstract

An in-body real-time photosensitive blood pH sensor is prepared from an ordinary optical fiber and an pH sensing film composed of the luminous electrochemical substance with high sensitivity to pH and the polymer containing phosphatide group through coating said pH sensing film on the terminal of said optical fiber. Its preparing process is also disclosed.

Description

technical field

[0001] The invention relates to the field of medical equipment and materials, in particular to an in vivo real-time light-sensitive blood pH sensor and a preparation method thereof. Background technique

[0002] The development of modern medicine, especially the rescue of clinical critically ill patients, requires long-term minimally invasive real-time detection of various parameters of the human body, including blood pH. At present, the pH measuring instrument is mainly based on the electrode method. It has the problem that the sensor and the blood contact with the blood for a certain period of time, and the surface is adhered by platelets and other proteins to cause failure. In other fields such as bioreactors Sensors for other applications also have similar biological contamination problems.

[0003] Phosphorylcholine is the main component of the phospholipid head in the outer layer of biological cell membranes. Polymers containing phosphorylcholine group...

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