The invention discloses a novel stone tablet rubbing protective agent and a preparation method thereof. The protective agent is mainly prepared from, by mass, 5.6-11.5 parts of cyclododecane and 10.5-21 parts of fluorine polymer. Accordingly, cyclododecane is adopted as one of the main raw materials, and cyclododecane has complete hydrophobicity and can be applied to cultural relics sensitive to water or an aqueous solution to serve as a waterproof barrier coating. Daikin GM-105D is selected as the applied fluorine polymer, and the fluorine polymer has the excellent heat resistance, chemical resistance, weather resistance, stain resistance, electrical characteristics and the like and has the unique properties such as non-sticky performance and self-lubricating. Accordingly, cyclododecane and the fluorine polymer are compounded to form a composite material, and the strength, permeability, alkali resistance, stain resistance, heat resistance and weather resistance of the product are improved. The evaporation speed of cyclododecane can be effectively slowed down, evaporability of the product is lowered, and the product can be removed freely.