82results about "Heat insulating devices" patented technology

The invention discloses a gene detection method, a gene detection kit and gene detection equipment. The gene detection method comprises the following steps of arranging a plurality of separation cavities in the kit, blocking the every two adjacent separation cavities by a plunger, and adding a cracking liquid, a cleaning liquid and a reaction liquid into each separation cavity; when a sample is detected, pushing each plunger, aligning a plunger hole of each plunger with the corresponding separation cavity, and further conducting each separation cavity; utilizing an electromagnetic control type to control magnetic beads in the kit to drive the to-be-tested sample to sequentially pass through the separation cavities, and then sequentially cracking, cleaning and reacting; finally, performing optical detection on the gene in the reaction liquid from the exterior.

A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and / or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° C. The pre-soaking process can, for example, be performed during sample transport or during extended periods of storage, such as over a weekend.

A closure for a container includes: (a) an inner cylindrical wall having first and second ends and defining a space; (b) an outer cylindrical wall opposite the inner cylindrical wall and having said first and second ends to form an outer surface of the closure; (c) a first end wall extending across said first end, wherein said first end wall comprises a recess extending a least partially into said space, and a first set of threads disposed on said recess. In a preferred embodiment, a second set of threads is disposed on said inner or outer cylindrical wall having a direction which is opposite that of the first set of threads. A combination container and a closure includes the closure as described above and a container having an opening at one end adapted to receive the closure. An apparatus removes and installs a closure on the container and includes: a threaded rotatable spindle adapted for threading into a closure having a threaded depression and for applying a rotational force to remove the closure; and a clutch having an element adapted to engage the closure and apply a rotational to the closure. The apparatus can be used on an analyzer, such as a diagnostic analyzer.

Cryogenic devices are provided in which solid carbon dioxide (dry ice) is used to maintain a temperature zone in which samples can be manipulated under conditions in which the sample is maintained at a temperature below −50 C.

Disclosed is a transport container for shipping frozen material, particularly biological tissue samples. Said transport container comprises a jacket-shaped insulation (superinsulation) and a removable inner container (44) which is provided with at least one coolant chamber (47) with a coolant filling (47'), and at least one chilling chamber (46) that is located inside the coolant chamber (47). The coolant, e.g. mercury having a melting temperature of about -39 DEG C, is permanently and hermetically enclosed in the coolant chamber (47) and is solidified in a freezing process using liquid nitrogen, for example, before being shipped. The chilling chamber (46), and thus the sample, is maintained at said temperature level during shipping while the coolant or mercury melts slowly.

A closure for a container includes: (a) an inner cylindrical wall having first and second ends and defining a space; (b) an outer cylindrical wall opposite the inner cylindrical wall and having the first and second ends to form an outer surface of the closure; (c) a first end wall extending across said first end, wherein the first end wall comprises a recess extending a least partially into the space, and a first set of threads disposed on the recess. An apparatus usable on a diagnostic analyzer container and includes: a threaded rotatable spindle adapted for threading into a closure having a threaded depression and for applying a rotational force to remove the closure; and a clutch having an element adapted to engage the closure and apply a rotational to the closure.

A system for maintaining a biological sample within a desired temperature range during transport. Preferably, the system includes a container defining an inner chamber; a specimen receptacle for housing a biological sample, wherein the specimen receptacle is configured to be placed within the inner chamber of the container; a heat source configured to be placed within the inner chamber of the container; and a heat sink. The heat sink is configured to be positioned between the heat source and the specimen receptacle, thereby preventing direct heat transfer between the heart source and the specimen receptacle. Certain embodiments also relate to a method for maintaining biological samples within a desired temperature range during transport, using at least some of the system components. Preferably, the components used with the method are configured to maintain the sample at a temperature greater than 0° C. and less than approximately 37° C. during shipping.

A heat block with an insulating collar for use in thawing frozen cells and viruses for vaccine production.

An apparatus for holding a test tube in which insulated isothermal polymerase chain reaction is performed includes a heat sink and a tube rack. The heat sink has a main body with a through hole for insertion of the test tube. The through hole has a relatively big diameter section and a relatively small diameter section located below the relatively big diameter section. The tube rack is mounted on the heat sink for insertion of the test tube. The apparatus can ensure that the temperature at the liquid level of the reaction mixture is lower than the temperature suitable for conducting the primer annealing step in the polymerase chain reaction process.

A sample support (100, 101, 102, . . . ), in particular for cryopreservation of biological samples, is described and includes: a holder part (10) with a sample receiving chamber (11), a retaining device (12, 13) on which a sample can be disposed, and support connecting elements (14, 15) which are directed at opposite holder part ends (16, 17) and are formed to fit together so that a plurality of holder parts (16) can be put together. A sample store (200), which includes an assemblage of a large number of such sample supports, and a method for the cryopreservation of biological samples, are also described.

The invention provides a microfluidic chip component capable of realizing digital PCR (polymerase chain reaction) quickly and application thereof. The microfluidic chip component comprises at least one microfluidic chip, a radiator arranged below the microfluidic chips and a heater arranged above the microfluidic chips, a semiconductor refrigerator and a heat conduction plate arranged above the same are arranged between the radiator and the microfluidic chips, and a thin film layer is bonded at the bottoms of the microfluidic chips and is in butt connection with the heat conduction plate. Liquid drop generation and PCR on a same microfluidic chip are realized, and transfer after liquid drop generation in the prior art is avoided; by bonding the thin film layer, heat capacity of a heated object is reduced, so that quick temperature increase and decrease is realized.

The invention discloses a simulation system for a high-low-temperature environment of a controlled flexible cavity body. The simulation system comprises a low-temperature cold source supply device, a vaporizer, an electric heater, an upper static pressure chamber, a lower static pressure chamber, a soft cover, an upper fixing piece, a lower fixing piece, a temperature sensor, a data acquisition instrument, a lifter device, a controller, a plurality of valves and a plurality of pipelines, wherein the soft cover is formed by compounding a plurality of aluminum-coated film reflection layers with fiber paper at an interval, the top of the soft cover is hermetically connected with the upper static pressure chamber through the upper fixing piece, and the bottom of the soft cover is hermetically connected with the lower static pressure chamber through the lower fixing piece, so that a volume-changeable sealed chamber is formed; the low-temperature cold source supply device is used for providing a low-temperature cold source and enabling a temperature field space of the soft cover to be in a low-temperature state through the vaporizer and the valves; the electric heater is used for providing heat and enabling the temperature field space of the soft cover to be in a high-temperature state; the lifter device is connected with the soft cover through the lower fixing piece and the lower static pressure chamber to drive the soft cover to reciprocate up or down. According to the simulation system, flexible high-low-temperature field can be generated and controlled through lower cost and a simple process.

An apparatus for holding a test tube in which insulated isothermal polymerase chain reaction is performed includes a heat insulating mount and a heating member. The heat insulating mount has a main body provided with a receiving space for receiving a bottom of the test tube, a lateral channel communicated between the receiving space and an ambient environment, and an upper channel communicated between the receiving space and the ambient environment for insertion of the test tube. The heating member is inserted into the lateral channel for stopping at the bottom of the test tube. The apparatus can minimize the influence caused by the high temperature generated from the heat source on the heat dissipation of the reaction mixture in middle and upper sections of the test tube. The apparatus is suitable for the fluorescent detection of PCR reaction.

The invention relates to a transport container (1) comprising a superinsulation in the form of an evacuated insulating container (2) comprising a vacuum maintaining material (55). The transport container is provided with a cooling container (16) comprising a heat-conducting metal wool filling (57) and an organic coolant which undergoes a solid / liquid phase change in the temperature range of between −30° C. and −850° C. and has a heat of fusion of at least 50 J / ml. A slim cylindrical sample chamber (24) is used to receive deep-frozen tissue samples (26), said chamber being surrounded by the cooling container (16) and merging into a long neck opening (25) forming a single component therewith, said opening being largely filled by the insulating shaft (30) of a screwable plug (28) and sealed from the sample chamber (24). The air in the ring gap (32) created can be evacuated by means of an evacuating system (48). The plug (28) is provided with a stopper (38) protruding into the sample chamber (24) and a data logger (41) for recording the temperature in the sample chamber (24). Following the freezing of the coolant, the transport container (1) enables distribution times and intermediate storage of up to 14 days without any risk of damage to the tissue samples (26) received therein.

The present disclosure provides coding and amino acid sequences for a Campylobacter jejuni pilus protein (and from other species as well). This protein, when administered to a human or animal, elicits the expression of an immune response to Campylobacter jejuni, with the result that colonization and / or infection by this organism is reduced. Recombinant protein or biofilm material comprising the pilus protein is formulated into immunogenic compositions, especially for mucosal administration. Thus, the present invention provides methods for improvement of the microbial quality of food products including poultry, eggs, meat and dairy products, and indirectly of plant foods that may come in contact with agricultural waste, either from fertilization or from irrigation water.

One aspect of the invention relates to a temperature control device for controlling the temperature of a container, comprising: at least one heating region having at least on heating element, and at least one cooling region having at least one cooling element, wherein the temperature control device is formed to be flexible, at least in some regions, wherein the temperature control device can be transferred from an open position to an arrangement position by flexible deformation, and wherein the temperature control device, in the arrangement position, can be arranged on a wall of the container in a form-fitting manner, at least in some regions, and can be thermally contacted such that the temperature of the container can be controlled by means of the at least one heating element and the at least one cooling element.

A nucleic acid analysis apparatus with isothermal based amplification includes a chamber, a fluid delivery unit, a thermal unit, a rotational driven unit and at least one optical unit. The chamber includes a cartridge mounted therein. The fluid delivery unit is connected with the chamber and adapted to transport reagents within the cartridge for sample purification and / or nucleic acid extraction. The thermal unit is disposed in the chamber and adapted to provide a predefined temperature for nucleic acid amplification. The rotational driven unit is connected with the chamber and comprises a motion control unit, wherein the motion control unit is capable of pressing the cartridge during sample purification and / or nucleic acid extraction and rotating the cartridge with a predefined program during nucleic acid amplification and / or detection. The at least one optical unit is disposed on the chamber and includes plural optical components for detection.

An apparatus for holding a test tube in which insulated isothermal polymerase chain reaction is performed includes a heat sink and a tube rack. The heat sink has a main body with a through hole for insertion of the test tube. The through hole has a relatively big diameter section and a relatively small diameter section located below the relatively big diameter section. The tube rack is mounted on the heat sink for insertion of the test tube. The apparatus can ensure that the temperature at the liquid level of the reaction mixture is lower than the temperature suitable for conducting the primer annealing step in the polymerase chain reaction process.

A nucleic acid analysis apparatus includes a casing, a main frame, a fluid delivery unit, a thermal unit, a driving unit, and at least one optical unit. The casing has an upper casing and a lower casing. The main frame is disposed in the lower casing and has a chamber for mounting a cartridge therein. The fluid delivery unit is adapted to transport reagents within the cartridge for sample purification and / or nucleic acid extraction. The thermal unit is adapted to provide a predefined temperature for nucleic acid amplification. The driving unit is disposed in the lower casing and connected with the main frame, and includes a motion control unit capable of pressing the cartridge during sample purification and / or nucleic acid extraction and rotating the cartridge with a predefined program during nucleic acid amplification and / or detection. The optical unit includes plural optical components for detection.

The invention provides an integrated microsphere preparation device. The integrated microsphere preparation device is characterized by comprising a microsphere forming line, a microsphere post-processing tank, a connecting and transferring device and a refrigerating device, wherein the microsphere forming line is used for processing liquid materials into primary cured microspheres, the microsphere post-processing tank is used for subjecting the primary cured microspheres to further curing, temperature reversion and washing, the connecting and transferring device is used for conveying the microspheres produced by the microsphere forming line into the microsphere post-processing tank, the refrigerating device is used for subjecting the microspheres treated by the microsphere post-processing tank to filling and freeze drying, and the microsphere forming line, the microsphere post-processing tank, the connecting and transferring device and the refrigerating device are arranged in a sterile isolation hood. The integrated microsphere preparation device integrates microsphere preparation steps of forming, curing, collecting, washing and sieving previously operated by five units, so that the whole technological process can be conducted in a sterile isolator, and simplicity and convenience in sterile production are achieved; the integrated microsphere preparation device is simple and convenient to operate, safe and environment friendly, thereby meeting industrial demands.

The invention provides an electric furnace device for component fire protection design and fire protection supervision and a using method. The using method comprises the following steps of: step 1. determining a test scene; step 2. installing the device in position on site; step 3. installing a test sample to be tested, to be specific, step 3A, adopting installation steps described in specifications when a cube test sample is adopted, and step 3B. adopting installation steps described in specifications when a cylindrical test sample is adopted; step 4. unexposed surface heat preservation selection, to be specific, step 4A. when the test sample to be tested is the cube test sample or the cylindrical test sample, adopting installation steps of a heat insulation cover described in specifications, and step 4B. the heat insulation cover is not used; step 5. preparing furnace temperature setting; step 6. selecting a control mode, to be specific, step 6A. using the control test process of a control part, and step 6B, using the control test process of a mobile terminal; and step 7. completing the whole test process, and storing the electric furnace device and the mobile terminal. The electric furnace device can simulate the true boundary relationship between a protected material and a heat insulation material, provides a simple and reliable equivalent heating curve setting method, canquickly form a test report, and greatly improves the efficiency of supervision and law enforcement.

The invention discloses a high-temperature environmental vibration test method and a heat insulation switching device. The test method is carried out based on a high-temperature environmental vibration test system which comprises a high-temperature environment generation device, the heat insulation switching device, an excitation source and a circulating cooling device. A hole channel is formed inthe heat insulation switching device; a test piece is arranged on the heat insulation switching device; the excitation source provides excitation force which acts on the heat insulation switching device to drive the test piece to vibrate; and the heat insulation switching device is connected to the external circulating cooling device through a pipeline, so a circularly flowing cooling medium circularly flows in the heat insulation switching device for heat exchange, and the temperature of the excitation source is not influenced by a high-temperature environment. In this way, the test method is reasonable in design, and can meet the requirements of high-temperature environmental vibration tests at a temperature of 1200 DEG C.

The present invention relates to a cooled sample subjected to freezing treatment, or the like, preventing the formation of condensation and frost-like substances and loads the sample into a sample holder for observation using a charged particle beam device. A cryostation system of the present invention is provided with a main body for storing a sample and a lid unit mounted above the main body. The main body is divided into a first space and a second space by a partition member. The first space accommodates a cooling medium for cooling the sample. The second space has, disposed therein, a heating unit for heating the cooling medium accommodated in the first space. The lid unit has, formed therein, a discharge port for discharging the gas generated by the heating of the cooling medium to the outside.

A system for determining drug effectiveness on a plurality of cells is described. The system includes flowing a ferro-fluid mixed with a plurality of biological cells through an inlet portion of a cartridge, the cartridge comprising a plurality of micro-fluidic channels, the inlet is in communication with a portion of each of the plurality of channels, applying a magnetic field proximate at least one of the inlet portion and the plurality of micro-channels, wherein the magnetic field is configured to apply an indirect force on the mix, separating biologic cells according to at least a first type as the mix flows in a first direction; and directing at least the first type of cells toward a first sensor functionalized with receptors via at least one of the micro-channels, the sensor arranged proximate to a second portion of at least one of the micro-channels downstream from the first inlet portion.

A biologic sample preparation system that prepares samples for processing includes a frame defining a horizontal plane, a pipette assembly, a sample module and an extraction module. The pipette assembly includes a first pipette. The pipette assembly is movably mounted to the frame in a direction substantially perpendicular to the horizontal plane during operation. The sample module includes a sample plate and is movably mounted to the frame. The sample module is movable substantially parallel to the horizontal plane at least from a sample area spaced from the pipette assembly and a working area proximate the pipette assembly. The extraction module includes an extraction plate and is movably mounted to the frame. The extraction module is movable substantially parallel to the horizontal plane at least from an extraction staging area spaced from the pipette, assembly and the working area proximate the pipette assembly.

An experimental method and apparatus for simulating the adiabatic reaction in laboratory is characterized by that the miniature single-tube reactor is used and solid bed layer of catalytic reactor is heated according predictated value to generate an artificial temp gradient. It is suitable for the strong heat releasing reaction (alkylation, oligorization, or hydrogenation).

A system for determining drug effectiveness on a plurality of cells is described. The system includes flowing a ferrofluid mixed with a plurality of biological cells through an inlet portion of a cartridge, the cartridge comprising a plurality of microfluidic channels, the inlet is in communication with a portion of each of the plurality of channels, applying a magnetic field proximate at least one of the inlet portion and the plurality of micro-channels, wherein the magnetic field is configured to apply an indirect force on the mix, separating biologic cells according to at least a first type as the mix flows in a first direction; and directing at least the first type of cells toward a first sensor functionalized with receptors via at least one of the micro-channels, the sensor arranged proximate to a second portion of at least one of the micro-channels downstream from the first inlet portion.

The invention discloses preventive medicine sample transportation equipment with a heat preservation function, and relates to the technical field of transportation equipment, the preventive medicine sample transportation equipment comprises a storage box, a sliding groove is formed in the inner wall of the lower side of the storage box, and two first sliding blocks are slidably connected into the sliding groove. According to the preventive medicine sample transportation equipment with the heat preservation function, a plurality of placement holes are formed in a placement disc, a partition plate is arranged between every two adjacent placement holes, and a user takes out test tubes on the lower sides of sampling holes through a supporting plate by controlling an electric push rod to extend, and thus other sample test tubes are prevented from being exposed in the external environment when samples are taken by the device for detection, the protection effect on the samples is improved by utilizing the device, and the problems that the samples are easy to deteriorate due to poor heat preservation effect of an existing transportation device, and the other samples are exposed together when the samples are taken by the existing device, and the sample is liable to be contaminated and the detection result is influenced can be solved.