The invention provides a cultivation method of seedless watermelons and belongs to the field of agricultural planting. The cultivation method specifically comprises the following steps: firstly, selecting and preparing soil suitable for seedless watermelons to grow, and applying a base fertilizer prepared from a self-made organic fertilizer, a phosphorus fertilizer and a potassium fertilizer to the soil, wherein the self-made organic fertilizer is prepared by carrying out mixed fermentation on cucumber stems, straws, mushroom residues, watermelon vines, cassava wastes, orange peels, pig manure, pond sludge, faecal matters and a corrosion catalyst; then, placing the treated seedless watermelon seeds into a seedling raising tray for raising seedlings; next, transplanting the seedlings to a field, and watering for field planting; and carrying out reasonable management until harvesting. The invention provides the cultivation method of the seedless watermelons. By using the method, the survival rate and taste quality of the seedless watermelons can be improved, resources can be saved, artificial consumption can be reduced, furthermore, the nutrient value of a product is increased, and therefore, the cultivation method is suitable for large-scale systematized plantation and capable of increasing the production and income of growers.