Real-time acousto-optic imaging method based on acoustic lens and polarizing inspection

A technology of photoacoustic imaging and acoustic lens, which is applied in ultrasonic/acoustic/infrasonic diagnosis, acoustic diagnosis, infrasonic diagnosis, etc. It can solve the problems of inability to monitor tissue changes in real time and take a long time, and achieve non-damaging sensitivity and improve sensitivity. Effect

CN100493442CInactive Publication Date: 2009-06-03SOUTH CHINA NORMAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2009-06-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

A real-time optico-acoustic imaging method based on acoustic lens and polarization detection is disclosed. The acoustic lens is used to generate the acoustic pressure distribution of biologic tissue duto optico-acoustic effect and couple it to an imaging plane for directly imaging on it. A polarization analyzing method is used to convert said acoustic pressure distribution to light intensity distribution, which is recorded by CCD to obtain a clear image of a tissue layer. Its apparatus is composed of transparent flexible rubber layer, optical fiber, acoustic lens, laser, 1 / 4 wave plate, polarization analyzer, CCD, computer, and cylindrical cavity made of aluminum.
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Description

technical field

[0001] The invention relates to photoacoustic imaging technology, in particular to a real-time photoacoustic imaging method based on acoustic lens and polarization detection.

[0002] The invention also relates to devices used in said method. Background technique

[0003] Using optical imaging technology combined with modern advanced photoelectric detection technology to conduct non-invasive tomographic research on biological tissues has always been a research hotspot in optics, biomedicine and its interdisciplinary subjects, such as optical coherence tomography (OCT), Optical ultrafast time-resolved tomography and photon density wave imaging. Photoacoustic tomography (OACT) is an optical tomography technology with great potential and very attractive application prospects, because OACT uses the method of "light absorption-excitation photoacoustic signal-photoacoustic imaging". Imaging, it has many potential advantages. First, OACT uses the photoacoustic sig...

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Embodiment Construction

[0039] The present invention will be further described in detail below in conjunction with the embodiments and accompanying drawings, but the embodiments of the present invention are not limited thereto.

[0040] figure 1 It is the structural block diagram of the device of the present invention, by figure 1 It can be seen that the device of the present invention mainly includes a helium-neon laser 1 , a pulse laser 2 , a sample 3 , an acoustic lens 4 , a reflective film 5 , a 1 / 4 wave plate 7 , an analyzer 8 , a CCD 9 , and a computer 10 . Select each component to connect to form this device, wherein: laser 1 selects the helium-neon laser; Laser 2 selects the MOPO (Model: PRO2230) produced by American Spectrophysics Corporation, which can emit pulsed laser with a wavelength of 500nm-2000nm. In this embodiment, the selected wavelength is The 532nm green laser has a repetition period of 30HZ; the acoustic lens 4 is designed and processed by itself; the CCD 9 selects a sensor wi...