New-type of inorganic bone grafting material and its prepn and use

An inorganic and bone-grafting technology, applied in the field of new inorganic bone-grafting materials and composite artificial inorganic bone cement, can solve the problems of fast absorption, soft tissue filling, slow dissolution and absorption, etc., and achieve convenient storage and use, and good bone defect repair , The effect of simple preparation process
CN101020085AInactive Publication Date: 2007-08-22GENERAL HOSPITAL OF PLA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GENERAL HOSPITAL OF PLA
Publication Date
2007-08-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention is one kind of new inorganic bone grafting material and belongs to the field of medical material. The inorganic bone grafting material consists of beta-tricalcium phosphate grain in 20-80 wt% and alpha-calcium sulfate semihydrate powder in 20-80 wt%, and the alpha-calcium sulfate semihydrate powder form layered structure in the surface and / or pores of beta-tricalcium phosphate grain. Both beta-tricalcium phosphate and alpha-calcium sulfate semihydrate have excellent biocompatibility and excellent in vivo degrading performance, and the composite artificial bone grain may be used in repairing bone defect of different shapes. The composite artificial bone grain has wide material source, convenient use, excellent performance, simple preparation process, low cost and other advantages.
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Description

technical field

[0001] The present invention relates to a new type of inorganic bone graft material, its preparation method and application, in particular to a self-curing and absorbable composite artificial inorganic bone cement used in medical surgery for replacing and repairing bone tissue defects, its preparation method and The invention belongs to the field of medical materials. Background technique

[0002] Bone is composed of inorganic components and organic components, of which the inorganic components account for 60-70% of the dry weight, and the main component is hydroxyapatite (Ca 10 (PO 4 ) 6 ·5H 2 O) and a small amount of sodium salt, magnesium salt, etc., the organic component is mainly type I collagen. The size of the hydroxyapatite crystal is about 25-50nm×40nm×200-350nm, and the direction of the long axis (c-axis) of the crystal is consistent with the direction of the type I collagen fiber, forming a porous structure material with interconnected micropor...

Claims

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