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Cardiac and cerebral vascular disease treating medicine, the preparing method, the quality control method and the function thereof

A technology for cardiovascular and cerebrovascular diseases and drugs, which is applied in the application field of preparing drugs for treating cardiovascular and cerebral ischemia diseases, can solve problems such as affecting the quality of compound Danshen tablets, and achieve the effects of excellent quality, high active ingredients and high quantity

Active Publication Date: 2007-10-31
北京云威科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to some serious problems in the preparation process, quality standards, etc., the quality of Compound Danshen Tablets has been affected to a certain extent or even seriously.

Method used

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  • Cardiac and cerebral vascular disease treating medicine, the preparing method, the quality control method and the function thereof
  • Cardiac and cerebral vascular disease treating medicine, the preparing method, the quality control method and the function thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Embodiment 1: the method for extracting effective active site from raw material

[0095] The salvia miltiorrhiza, Radix Notoginseng and Ai Tablet medicinal materials used in the method of the present invention are purchased from the GAP production base, and other raw materials can be purchased from the market, and the equipment used is the extraction and processing equipment commonly used in the field of traditional Chinese medicine pharmacy.

[0096] (1) Obtaining of Salvia miltiorrhiza extract (Salvia miltiorrhiza extract mainly composed of salvia phenols and tanshinones)

[0097] The extraction method of the salvia miltiorrhiza extract with the total phenols of salvia miltiorrhiza and total ketones of salvia miltiorrhiza as main components is as follows: 2 -SFE technology extracts tanshinone compounds, takes Danshen medicinal material, cleans it and crushes it into coarse powder, and conducts CO in the SFE device 2- SFE extraction, the extraction conditions are: pre...

Embodiment 2

[0100] Embodiment 2: the preparation method of pharmaceutical tablet of the present invention

[0101] Get the salvia miltiorrhiza extract, the Radix Notoginseng root extract, the natural borneol and mix uniformly according to the ratio of 50-95%: 20-50%: 2-25%, weigh the mixed powder; get pregelatinized starch, sodium carboxymethyl starch, After passing through a 60-mesh sieve, mix with the above-mentioned mixed powder until uniform; then add absolute ethanol to make a suitable soft material, pass through a 18-mesh sieve, granulate, dry, and granulate; take magnesium stearate and mix evenly, using a Φ9.0mm shallow After arc punching the tablet, it is coated with film, the rotating speed of the coating pan is 20 rpm, the outlet air temperature is 35°C to 40°C, and the tablet bed temperature is 40°C to 45°C to obtain the medicine of the present invention.

Embodiment 3

[0102] Embodiment 3: Use the active ingredients of the medicine of the present invention to prepare capsules according to the conventional pharmaceutical preparation method with conventional adjuvant materials.

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Abstract

The invention discloses a compound medicine with salvia miltiorrhizae extract, notoginseng root extract and nature left-handed baras camphor (Ai slice with 1-borneol (l-Borneol)) as effective element, preparing method and application to cure heart and brain ischemia disease medicine, which is characterized by the following: incorporating all active element of salvia miltiorrhizae liposolubility and water-solubility of the medicinal preparation; possessing high content; coming from activate blood circulation and remove stasis effective position of notoginseng for Notoginsen triterpenes; possessing high purity and strong activator for 1-borneol. This invention adopts three grade quality control mode, which keeps high grade and uniform of product.

Description

technical field [0001] The present invention relates to a kind of traditional Chinese medicine compound and preparation thereof, its preparation method and application; , also known as Ai Pian) as a medicine of the active ingredient, its preparation method and its application in the preparation of medicines for the treatment of cardio-cerebral ischemic diseases. Background technique [0002] Salvia miltiorrhiza, the root of Salviamiltiorrhiza Bge., a plant of the genus Salvia miltiorrhiza Bge. in the family Lamiaceae, is a traditional and commonly used traditional Chinese medicinal material. Key drug collection introduction. For a long time, Salvia miltiorrhiza has been widely used as a therapeutic drug for various diseases, and it is a representative medicinal material of traditional Chinese medicine for promoting blood circulation and removing blood stasis. Salvia miltiorrhiza mainly contains diterpene quinones, phenolic acid compounds, and also contains tannins, polysac...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K9/20A61K9/48A61K9/14A61K9/16A61K9/08A61K9/10A61K9/00A61P9/10
Inventor 廖幼鸣邓文龙
Owner 北京云威科技有限公司
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