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Anti-diarrhea yolk antibody feed additive and injection for goat and preparation thereof

The technology of feed additive and egg yolk antibody is applied in the field of anti-sheep diarrhea egg yolk antibody feed additive, injection and preparation thereof, and achieves the effects of remarkable effect, low cost and easy use.

Inactive Publication Date: 2008-09-10
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] At present, there is no report about the preparation method of yolk antibody against sheep rotavirus, sheep Escherichia coli and sheep Clostridium welchii type B

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] An anti-sheep diarrhea egg yolk antibody feed additive is characterized in that it is a single vaccine prepared from sheep rotavirus, sheep Escherichia coli, sheep Clostridium welchii type B, or sheep rotavirus and / or sheep Escherichia coli and / or sheep rotavirus The combined vaccine prepared by Clostridium welchii type B was used to immunize non-immune laying hens, and then the egg yolk of the immune laying hens was collected, extracted and prepared.

[0038] The preparation method of anti-sheep rotavirus, sheep Escherichia coli and sheep Clostridium welchii type B egg yolk antibody feed additive, the implementation steps are as follows:

[0039] (1) Separating ovine rotavirus and / or ovine Escherichia coli and / or ovine Clostridium welchii type B for proliferation and culture, and preparing ovine rotavirus, ovine Escherichia coli and ovine type B Clostridium welchii for antigenicity Bacterial triple vaccine.

[0040] (2) Utilize the prepared sheep rotavirus, sheep Esch...

Embodiment 2

[0043] An anti-sheep diarrhea egg yolk antibody injection, characterized in that it is a single vaccine prepared from sheep rotavirus, sheep Escherichia coli, sheep Clostridium welchii type B, or sheep rotavirus and / or sheep Escherichia coli and / or sheep B The combination vaccine prepared by Clostridium welchii type was used to immunize non-immune laying hens, and then the egg yolk of the immune laying hens was collected, extracted and prepared.

[0044] The preparation method of anti-sheep rotavirus and sheep Escherichia coli egg yolk antibody injection, the implementation steps are as follows:

[0045] (1) Isolate ovine rotavirus and / or ovine Escherichia coli for propagation and culture, and prepare an ovine rotavirus and ovine Escherichia coli dual vaccine when it has antigenicity.

[0046] (2) Utilize the prepared sheep rotavirus and sheep Escherichia coli dual vaccine to immunize non-immune laying hens, the immunization dose is 1.0ml in the first round of immunization inj...

Embodiment 3

[0049] The preparation method of anti-sheep rotavirus, sheep Escherichia coli and sheep Clostridium welchii type B egg yolk antibody injection, the implementation steps are as follows:

[0050] (1) Separating ovine rotavirus and / or ovine Escherichia coli and / or ovine Clostridium welchii type B for proliferation and culture, and preparing ovine rotavirus, ovine Escherichia coli and ovine type B Clostridium welchii for antigenicity Bacterial triple vaccine.

[0051] (2) Utilize the prepared sheep rotavirus, sheep Escherichia coli and sheep Clostridium welchii type B triple vaccine to immunize non-immune laying hens, and the immune dose is 1.0ml during the first round of immunization injection; For rounds of immunization injections, the immunization dose is twice that of the first immunization; after another 10 days, the third round of immunization injections is carried out, and the immunization dose is 4 times that of the first immunization; after that, immunization is performed...

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Abstract

The present invention relates to a feed additive and an injection of a yolk antibody resisting the diarrhea in sheep and a preparation method thereof. The feed additive and the injection of the yolk antibody resisting the diarrhea in sheep are extracted and prepared by the collected yolk of the immunized laying hens which are immunized by the univalent vaccines respectively prepared by sheep rotavirus, sheep colon bacillus and sheep clostridium welchil type-B or the combined vaccines prepared by the sheep rotavirus and / or the sheep colon bacillus and / or the sheep clostridium welchil type-B. The yolk antibody resisting the diarrhea in sheep prevents the diarrhea disease by improving the antibody level of a sheep organism for corresponding pathogenic microorganism causing the diarrhea. The present invention has beneficial effects that the feed additive of the yolk antibody resisting the diarrhea in sheep is convenient for feeding sheep and has obvious preventing and curing effect. The injection of the yolk antibody resisting the diarrhea in sheep is used after the sheep catches the disease, which has faster medicinal effect. The feed additive and a injection of a yolk antibody resisting the diarrhea in sheep and the preparation method thereof has obvious curative effect, low cost, fast acting, no toxic and side effect, no drug-resistant strain which can be produced, simple preparation, wide raw material source, convenient use and easy popularization.

Description

technical field [0001] The invention belongs to the field of feed and medicine, in particular to an anti-sheep diarrhea egg yolk antibody feed additive and injection and a preparation method thereof. Background technique [0002] Sheep diarrhea is more common in lambs, especially in lambs less than 15 days old, and rare in adult sheep. Sheep diarrhea is usually associated with small intestinal diseases, mainly two pathological processes of hypersecretion and malabsorption. The lamb’s intestinal mucosa is underdeveloped, the acidity of the gastric juice is low, and the activity of the enzyme is low. Under the action of adverse factors, the contents entering the gastrointestinal tract are prone to incomplete decomposition and fermentation, and the intermediate products of this fermentation stimulate intestinal peristalsis and cause diarrhea. Intestinal digestive dysfunction changes the concentration of hydrogen ions in the chyme, creating an environment conducive to the repro...

Claims

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Application Information

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IPC IPC(8): A61K39/42A61K39/40A23K1/00C07K16/08C07K16/12A61P31/14A61P31/04A23K20/00A23K40/00
Inventor 古长庆
Owner TIANJIN SHENGJI GRP CO LTD
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