Uses of smoked plum extract against virus, bacteria, mycoplasma or chlamydia of livestock and poultry

An extract and ebony technology, applied in the field of biomedicine, can solve the problems of lack of vaccines, the prevention and treatment of bacterial infectious diseases, etc., and achieve the effects of ensuring food safety, solving food antibiotic residues, and improving competitiveness.

Active Publication Date: 2008-12-10
何诚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In 2005, the Ministry of Agriculture issued a document prohibiting the application of broad-spectrum drugs (viralin, amantadine, rimantadine, acyclovir) used by humans to livestock and poultry In medicine, antiviral drug resistance is prevented from passing from livestock to humans. However, some infectious diseases in my country still lack effective vaccines to control (such as respiratory reproductive syndrome, porcine myocarditis, pig unknown high fever, etc.), and the development of effective Drugs to prevent these diseases
Due to the abuse of antibiotics and the emergence of drug resistance, it is more difficult to prevent and treat bacterial infectious diseases

Method used

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  • Uses of smoked plum extract against virus, bacteria, mycoplasma or chlamydia of livestock and poultry
  • Uses of smoked plum extract against virus, bacteria, mycoplasma or chlamydia of livestock and poultry
  • Uses of smoked plum extract against virus, bacteria, mycoplasma or chlamydia of livestock and poultry

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 The preparation of ebony extract or effective part

[0024] Crush 1kg of ebony plums, then pass through a 10-mesh sieve, add 4-5kg of water to soak the sieve, decoct 3 times, 2-6 hours each time, collect the filtrate 3 times, concentrate to 1-1.5kg, and then use acetic acid Soak in 3-6 times the amount of ethyl ester, soak for 5-10 times continuously, collect the filtrate, recover ethyl acetate, and obtain the ebony extract;

[0025] After dissolving the ebony extract in methanol, mix it with silica gel 1-1.5 times (weight / weight), let it dry naturally, put it on a silica gel column, and use 100% chloroform, 90% chloroform (chloroform / methanol=9:1), 80% chloroform (chloroform / methanol=8:2), chloroform / methanol (2:1), chloroform / methanol (1:1), chloroform / methanol (1:1) / 1% formic acid, chloroform / methanol (1:1) 2) / 1% formic acid; collect 100% chloroform eluted fraction to obtain active ingredient I; collect 90% chloroform eluted fraction to obtain active in...

Embodiment 2

[0030] The preparation of embodiment 2 ebony extract granules and oral liquid

[0031] 100g of ebony extract was dissolved with 500ml of 95% ethanol, and 20g of sodium polyacrylate, 20g of sodium carboxymethylcellulose and 1200g of dextrin were added. Add medicinal starch 660g again, make granule 2000g according to conventional method.

Embodiment 3

[0032] The preparation of embodiment 3 ebony extract oral liquid

[0033] Dissolve 100g of ebony extract in 500ml of 95% ethanol, filter with a 100-mesh filter cloth, add 100g of sodium carboxymethylcellulose, mix well, dilute to 2000ML with water and pack into 100ML / bottle of oral liquid.

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PUM

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Abstract

The present invention discloses the application of ebony extract or effective parts (I, II and III) in preventing and remedying livestock and poultry viral disease, bacterial disease, mycoplasma disease and chlamydia disease. Tests in vitro and in vivo show that the ebony extract or effective parts (I, II and III) have the effects of preventing and inhibiting poultry flu virus, newcastle disease virus, infective bronchitis virus, and the like, and can effectively kill pathogenic bacteria causing the animal disease at the same time, such as bovine streptococcus agalactiae, bovine gold staphylococcus, bovine colon bacillus, chicken colon bacillus, etc. In addition, the ebony extract or effective parts can effectively prevent and remedy the poultry chlamydia disease and mycoplasma disease.

Description

technical field [0001] The invention relates to a new medical application of the ebony extract, in particular to the use of the ebony extract in resisting livestock and poultry viruses, bacteria, mycoplasma and chlamydia, and belongs to the field of biomedicine. Background technique [0002] Since the beginning of the 21st century, major livestock and poultry diseases have continued to break out all over the world, which not only seriously hindered the healthy development of animal husbandry, but also caused a series of public health emergencies. Major epidemics such as coccidiosis and foot-and-mouth disease have caused great harm to people's health and social stability. Therefore, the research and creation of new biological veterinary drugs has become a major national demand to ensure the development of my country's animal husbandry, maintain people's health and life safety, maintain social stability and promote economic development. [0003] Fuctus Mume (Fuctus Mume) is p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P31/00A61P31/04A61P31/12A61K131/00
Inventor 何诚斯建勇张发明李应超
Owner 何诚
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