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A technology of transfer body and external gel, which can be applied to medical preparations without active ingredients, medical preparations containing active ingredients, medical raw materials derived from arthropods, etc. Product listing and literature reports, etc., to achieve no treatment pain, no toxic side effects, and simple composition
Inactive Publication Date: 2009-01-28
王悦
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Abstract
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Problems solved by technology
Injections will bring pain to patients, and most oral drugs have adverse reactions, and the therapeutic effect is also limited
A gel for external use prepared with natural medicine as the main component and supplemented with transfer body transdermal absorption technology. No product is listed or reported in the literature.
Method used
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Embodiment 1
[0021] Prescription composition:
[0022] A: 25g dew honeycomb, 25g chrysanthemum, 25g terrazzo, 45g honeysuckle, 45g raw gypsum, 45g raw barley, 45g Sichuan achyranthes, 35g crocus, 35g atractylodes, 35g cork, 35g red peony, 3 centipedes, soap thorns 20g, Yuan Hu 20g
[0027] 1. Add 7-8 times the amount of water to decoct the 14 herbs in group A twice, the first time for 2 hours, the second time for 1 hour, combine the two decoctions, precipitate with 3 times the amount of ethanol, filter and concentrate to 1: 2.
[0028] 2. Dissolve the carbomer with deionized water for 10 hours, add the extract of group A and colchicine, fully stir and dissolve, and let it stand for 10-20 hours.
[0029] 3. Soybean phosphatidylcholine (SPc) was dissolved in ethanol, mixed ...
Embodiment 2
[0032] Prescription composition:
[0033] A: 35g dew honeycomb, 35g chrysanthemum, 35g terrazzo, 50g honeysuckle, 50g raw gypsum, 55g raw barley, 50g Sichuan achyranthes bidentata, 50g crocus crocodile, 45g herb atractylodes, 50g phellodendron, 55g red peony root, 8 centipedes, soap thorns 40g, Yuanhu 20g
[0035] C: 150 g of soybean phosphatidylcholine, 10 g of sodium cholate, 50 ml of ethanol, and 10 g of triethanolamine.
[0036] Made into 1000g
[0037] Preparation:
[0038] Its preparation method is with embodiment 1.
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Abstract
The invention provides an externally applied gel for treating gout, which is an externally applied medicine made from traditional Chinese medicine components such as nidus vespae, colchicine, a gel matrix, and the like., and by taking a coupling medium as transdermal carrier. The anti-gout gel can quickly eliminate redness, swelling, pain and fever symptoms of gouty arthritis, inhibit granulocyte infiltration and formation of lactic acid, reduce synthesis of uric acid, shorten and stop the acute attack of the gouty arthritis, prevent gout complications that threaten life, suspend tissue and organ damage caused by deposition of the uric acid, thus ensure that the illness of a patient is stabilized and can not deteriorate anymore for a long time. With the coupling medium adopted as the transdermal carrier of the medicine, the gel is characterized in that: a dermal hydration gradient can be naturally formed in the skin permeation course of the coupling medium, the gradient is independent of concentration when driving osmotic pressure difference, the gel has high deformability, can keep the components thereof unchanged after the skin permeation course and can permeate corneum of mammals through a plurality of transformation. The gel also has high transdermal efficiency, and full dermal permeabilities are not different between species and different parts. The gel avoids the deficiencies of injections and oral liquid medicines, is safe owing to the external use, and has no toxicity and side effects. The gel has simple components, low cost, requires no special devices and production conditions, and is available for large-scale industrialized production.
Description
Technical field: [0001] The invention relates to a transfer body gel for treating gout and a preparation method thereof, belonging to the technical field of medicines and preparation methods thereof. Background technique: [0002] Gout is an older disease. Hippocrates, the father of medicine in the 5th century BC, had records about the clinical manifestations of gout. In the 11th century, humans used the word Guta to refer to gout. At that time, it was believed that gout was caused by toxins in the body. Guta meant that the toxins entered the joints drop by drop and caused diseases. Guta was derived as Gout in the 13th century and is still used today. People in ancient times didn't know what caused gout, so they didn't have a good treatment method. They could only try abstinence, acupuncture, bloodletting, cold water or laxatives to treat it. Of course, there would be no significant effect. In 1679, Leeuwenhoek in the Netherlands first observed rod-shaped crystals of sodi...
Claims
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Application Information
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