Fluorescent chemical sensor for furadantin detection

Abstract

The invention discloses a fluorescence chemical sensor for detecting nitrofurantoin. 0.1-0.2ml of sensing film solution is coated on a polyfluortetraethylene board and is covered by a silylanized glass slide, and the fluorescence chemical sensor is manufactured after being polymerized by ultraviolet light and dried in room temperature, wherein, the sensing film solution is prepared by a method as follows: 15mg of methacrylate amide pyrene is solved in 0.2ml of N, N-dimethyl formamide; and 200mg of acrylamide, 0.4ml of hydroxyethyl methacrylate, 0.15ml of cross linker, 0.2ml of trolamine and 0.3ml of photosencitizer are added sequentially. The sensor has simple structure, good stability, the short responding time and the large extend of fluorescence and can be applied to the in-situ real-time detection of the nitrofurantoin, and the sensor has the high sensitivity, good selectivity and very wide application prospect.

Description

technical field

[0001] The invention relates to a fluorescent sensor, in particular to a fluorescent chemical sensor for detecting nitrofurantoin. Background technique

[0002] Aromatic fused ring compounds pyrene and other derivatives are a class of electronic materials with specific properties. The research on their luminescent properties and other photophysical properties is an extremely active topic, because pyrene and other derivatives are used in laser dyes. , biological fluorescent probe molecules, liquid crystal display materials, organic and inorganic fluorine and semiconductor materials and electroluminescent devices have been widely used. At the same time, pyrene has good stability and high quantum yield, so it is very suitable to be used as a fluorescent carrier to prepare photochemical sensors.

[0003] Nitrofurantoin (NFN), the molecular structure is as follows

[0004]

[0005] It is a drug used to treat urinary tract infections. After oral administration...

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