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Enteric microcapsule of garlic essential oil and production method thereof

A technology of garlic essential oil and production method, which is applied in the fields of pharmaceutical formulation, animal husbandry, organic active ingredients, etc., can solve the problems of low active ingredient content, unsatisfactory use, and inability of microcapsules to be enteric-coated, so as to achieve good fluidity and increase yield. Eating speed, the effect of reducing the damage of the digestive tract

Active Publication Date: 2012-07-04
湖南现代资源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Microcapsules prepared by spray drying method cannot be enteric-coated, and allicin will be released in the stomach. In addition, the active ingredient content of the microcapsules is relatively low, only about 10%, which cannot be used in feed processing.
The process of single coacervation method is complex, requires repeated coagulation, easy to stick, high production cost, requires a large amount of film-forming materials, and the active ingredient can only reach about 25%

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Preparation of enteric-coated microcapsules of garlic essential oil

[0042] 1) Preparation of garlic essential oil wet granules

[0043] Accurately weigh 40~55kg of medicinal grade silica and 5kg of corn starch, put them into the trough mixer, turn on the mixer and mix for 15 minutes, then add 40~55kg of garlic essential oil, continue to mix for 20 minutes, and then add Pre-prepared adhesive 40~50kg, mix for 10 minutes, stop.

[0044] Making wet granules Add the prepared granules to the hopper of the swing granulator, turn on the machine, and use a 20-mesh screen to make granules. The amount of each addition is 3~5kg. The resulting granules were neither loose nor cohesive into strands. The prepared wet granules should not be placed in the barrel for more than 1 hour.

[0045] 2) Rounding of wet particles

[0046] Put the wet granules made in step 1), 3~5kg each time, into the rotating centrifugal disc, after starting the blower, turn on the rotating centrifugal di...

Embodiment 2

[0052] Application of garlic essential oil enteric-coated microcapsules

[0053] 1) Application in piglet feed: Add 100~200g of garlic essential oil enteric-coated microcapsules per ton to the full-price compound feed of lactating piglets. From birth to 28 days before weaning, the average feed intake can be increased year-on-year. 5~7%, and the diarrhea rate decreased by 10~15% year-on-year. From the 28th day to the 65th day of nursery, the average feed intake can be increased by 7-13% year-on-year, the diarrhea rate can be reduced by 15-24% year-on-year, and the piglets have red and shiny skin.

[0054] 2) Use in dairy cow feed: Add 100~200g of garlic essential oil enteric-coated microcapsules per ton to the full-price compound feed of dairy cows, and the milk yield of dairy cows can be increased by 2.1~3.5%. Replacing antibiotics can reduce the incidence of mastitis by 6.4-11.2%.

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PUM

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Abstract

The invention provides an enteric microcapsule of garlic essential oil and a production method thereof, in particular to an enteric coating microcapsule of the garlic essential oil for animal green culture and the production method thereof. The production method comprises the steps: pelletizing the garlic essential oil, sorbent of white carbon black and corn flour by a wetting pelletizing method;polishing to be round; drying by a fluidizing bed and coating by crylic acid resin to generate the enteric coating microcapsule. The method can enhance the content of the garlic essential oil of the enteric microcapsule of the garlic essential oil to 30% to 50%, enhance the enteric release rate to more than 90% and basically cover the bad smell of the garlic essential oil. The made enteric microcapsule of the garlic essential oil can enhance animal food gathering quantity by 5% to 7% and reduce morbidity by 10% to 15%.

Description

technical field [0001] The invention relates to an enteric-coated microcapsule of garlic essential oil and a production method thereof, in particular to an enteric-coated microcapsule of garlic essential oil for green breeding of livestock and poultry and a production method thereof. technical background [0002] At present, antibiotics are widely used and abused in our livestock and poultry production. The main harm of the abuse of antibiotics in the breeding industry: the use of antibiotics as animal feed additives can make animals grow faster, have high disease resistance, and increase farmers' profits. However, the widespread use of antibiotics in animals will lead to the emergence of "resistant strains", making the original antibiotics ineffective and making it difficult to control animal bacterial diseases. After human consumption, people may develop drug resistance. The types of antibiotics currently used in agriculture have included almost all types of antibiotics ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/105A23K20/195
Inventor 胡光超曾清华莫少华王慧姣王晓武吴清华
Owner 湖南现代资源生物科技有限公司
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