Lactoalbumin antihypertensive peptide, preparation method and application thereof

A whey protein and blood pressure-lowering peptide technology, applied in albumin peptide, application, food preparation and other directions, can solve the problem that the whey protein blood pressure-lowering peptide has not been found yet, achieve normal blood pressure without influence, and the process is simple and easy to implement and convenient. The effect of industrial production
CN101736067AActive Publication Date: 2010-06-16北京双娃乳业有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
北京双娃乳业有限公司
Publication Date
2010-06-16

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Abstract

The invention discloses a lactoalbumin antihypertensive peptide and a preparation method and an application thereof. The lactoalbumin antihypertensive peptide is prepared by the following steps: after hydrating lactoalbumin solution, adjusting the pH value to 7.0-10.0, adding protease I for enzymolysis reaction; after reacting for 120-240 minutes, keeping reaction temperature constant; adjusting the pH value to 6.0-8.0; adding protease II into a reaction system to continue reacting; after reacting for 120-240 minutes, stopping reacting to obtain rough enzyme solution; inactivating enzyme in the rough enzyme solution, and adjusting the pH value to the isoelectric point of lactoalbumin; centrifuging to obtain supernate; adjusting the pH value of the supernate to 6.0-8.0; and collecting ultrafiltrate by a 10 kDa ultrafiltration membrane; and obtaining lactoalbumin antihypertensive peptide. Product analysis indicates that the prepared lactoalbumin antihypertensive peptide contains less than 2% of ash content, protein recovery rate approaches to 90%, TCA soluble nitrogen content is more than 85%, free amino acid content is 70.23 mu mol / mL, and ACE suppression ratio is more than 85%.
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Description

technical field

[0001] The invention relates to a whey protein hypotensive peptide, a preparation method and application thereof. Background technique

[0002] Hypertension is a chronic cardiovascular disease that plagues the world today. It has the characteristics of long incubation period and many complications. It is the most important pathogenic factor of coronary heart disease and heart and kidney failure. In recent years, the number of people suffering from high blood pressure worldwide has been increasing year by year, and the number is getting younger. Hypertension has become a major global public health problem. Hypertensive patients can only effectively control the development of the disease through long-term drug treatment. At present, the drugs used to lower blood pressure all have certain side effects. Active research on the blood pressure lowering functional factors in natural foods and the development of safe, natural and efficient antihypertensive peptide pr...

Claims

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